A Study on antioxidative property of edaravone derivatives by pulse radiolysis

Hata, Kuniki ; Katsumura, Yosuke; Lin, M.; Muroya, Yusa*; Fu, H.*; Kudo, Hisaaki*; Nakagawa, Keiichi*; Nakagawa, Hidehiko*

The reactivity of edaravone with some oxidative radicals ( $^{.}$ OH, N $_{3}$ $^{.}$ , Br $_{2}$ $^{.-}$ , SO $_{4}$ $^{.-}$ , CClO $_{3}$ O $_{2}$ $^{.}$ ) has been measured by pulse radiolysis. The reaction product of edaravone with $^{.}$ OH was different from those with other radicals. The rate constants of edaravone derivatives with $^{.}$ OH have also been determined by both direct measurement and a competition method using CO $_{3}$ $^{2-}$ and DMPO as competitors.

Language	:	Japanese
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Meeting title	:	第50回放射線化学討論会
Held date	:	2007/10
Location (city)	:	宇治
Location (country)	:	日本
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Keywords	:	no keyword
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Cooperating Institute	:	東京大学; 名古屋市立大学

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Registration No. : BB20072203
JAEA Abstracts No. :
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