Approach to the radiobiological study of using heavy-ion microbeam

Sakashita, Tetsuya; Suzuki, Michiyo; Hamada, Nobuyuki*; Ikeda, Daisuke*; Fukamoto, Kana; Yokota, Yuichiro; Funayama, Tomoo; Yanase, Sumino*; Higashitani, Atsushi*; Ishii, Naoaki*; Kobayashi, Yasuhiko

Using as a model multicellular organism, we push forward a heavy-ion microbeam irradiation individual-study. As for about 1.2 mm in a range of carbon ions in water, all cells and tissues of are microbeam irradiation objects. Sugimoto et al. showed DNA-damage-induced cell cycle arrest and apoptosis in locally irradiated areas of . We focus the nervous system of and study the effects of localized irradiation on salt chemotaxis learning behavior. However, the anesthetic method for fixation of animals is not usable because the whole body irradiation of Co rays affected only transition stage of the conditioning for salt chemotaxis learning. Thus, now we are constructing the heavy-ion microbeam irradiation system for living target .