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Effect of energetic heavy-ion irradiation on gene expression in ${it Caenorhabdits elegans}$

Higashitani, Atsushi*; Mori, Chihiro*; Kimura, Takafumi*; Ikenaga, Takahiko*; Takanami, Takako*; Sakashita, Tetsuya; Wada, Seiichi*; Hamada, Nobuyuki*; Kobayashi, Yasuhiko

We investigated the gene expression of ${it C. elegans}$ following carbon and $$gamma$$ irradiation using DNA microarray analysis. We observed the 187 and 297 upregulated genes after $$gamma$$ and carbon irradiation with 100 Gy, respectively, in which 51 genes were upregulated following both irradiations. On the other hand, the 358 and 388 genes were downregulated after $$gamma$$ and carbon irradiation, respectively.



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