Development of focused laser plasma X-ray beam for radiobiological applications

Nishikino, Masaharu; Ishino, Masahiko; Hasegawa, Noboru; Kawachi, Tetsuya; Sato, Katsutoshi*; Numasaki, Hodaka*; Teshima, Teruki*; Oshima, Shinsuke*; Okano, Yasuaki*; Nishimura, Hiroaki*

Recently, high energy, monochromatic X-rays emanating from laser-produced plasma (LPP) are attracting much attention as a new radiation source indispensable for high energy density physics, bioscience, and material sciences. Aiming at these applications, we have been improving performances of Ka lines emitted from LPP and soft X-ray lasers (XRLs). The monochromaticity is particularly important when X-rays are handled with a narrowband optics or used to selectively excite a specific material involved in matters. In addition, timeduration of such sources is typically an order of picosecond, and it could be comparable or even shorter than recovery time of radiatively-damaged biological cell, so that the LPP source can be a new source for investigating the mechanisms of irradiation survival and death of biological cells. We propose to develop an ultrashort, intense X-ray microbeam system to study the radiobiological effect and the bystander effect.