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Monte Carlo simulations of photon specific absorbed fractions in a mouse voxel phantom

Mohammadi, A.; Kinase, Sakae   

For preclinical assessments of several radiopharmaceuticals, specific absorbed fractions (SAFs) were evaluated using the voxel-based mouse phantom. The sources were assumed to be monoenergetic in the photon energy range from 10 keV to 4 MeV. The radiation transport was simulated using the Monte Carlo method. Consequently, it was confirmed that the photon SAFs for organ self-absorption are dependent on the masses of the source/target organs. It would appear that the photon SAFs for organ self-absorption are expressed by a continuous function of photon energy emitted by the source. The photon SAFs for organ cross-fire might be subject to the geometry effect such as size and shape of source/target and distance between the source and target.

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