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Production of an isomeric state of $$^{90}$$Y by fast neutrons for nuclear diagnostics

Nagai, Yasuki; Iwamoto, Osamu  ; Iwamoto, Nobuyuki  ; Kin, Tadahiro; Segawa, Mariko   ; Hatsukawa, Yuichi; Harada, Hideo   

We have noted that the isomeric state of $$^{90}$$Y with a half-life of 3.2 h as well as the ground state of $$^{90}$$Y can be populated significantly by $$^{90}$$Zr(n,p)$$^{90}$$Y and $$^{93}$$Nb(n,$$alpha$$)$$^{90}$$Y at a neutron energy of 14 MeV. On the basis of the result, we have proposed a new method to use $$^{90}$$Y radiopharmaceuticals containing the 682 keV isomeric state of $$^{90}$$Y for diagnostics and the ground state for therapy, since the isomeric state decays to the ground state of $$^{90}$$Y by emitting 480 and 203 keV $$gamma$$-rays, appropriate energies for imaging. $$^{90}$$Y radiopharmaceuticals containing $$^{90m}$$Y could solve long-standing problems associated with the use of $$^{90}$$Y together with $$^{111}$$In for imaging.

Language

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English

Journal

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Journal of the Physical Society of Japan

Volume

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78

Number

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11

Pages

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p.113201_1 - 113201_4

Publication Year/Month

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2009/11

Meeting title

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Held date

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Location (city)

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Location (country)

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Patent information

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PDF

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Paper URL

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https://doi.org/10.1143/JPSJ.78.113201

DOI for research data

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Keywords

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no keyword

Research Facility

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Press Release

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Article of JAEA R&D Review

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Cooperating Institute

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Accesses

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- Accesses

InCites™

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Percentile:37.21

Category:Physics, Multidisciplinary

Altmetrics

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