Carbon-ion microbeam induces behavioral change in the salt chemotaxis learning of

Sakashita, Tetsuya; Suzuki, Michiyo; Muto, Yasuko; Yokota, Yuichiro; Funayama, Tomoo; Hamada, Nobuyuki*; Fukamoto, Kana*; Kobayashi, Yasuhiko

To investigate the effects on the neuronal tissue (a nerve ring), we used the heavy-ion microbeam system. Well-fed adults of grown on the plate spread with the were used in all experiments. Anesthetized animals were irradiated locally with carbon-ion microbeams that were extracted into the air through an aperture. Immediately after microbeam irradiation, chemotaxis to NaCl of exposed animals was measured. Microbeam irradiation experiments in the both areas showed no significant effects on the ability of the salt chemotaxis learning. It indicates that the salt chemotaxis learning in is not affected by carbon-ion induced damage in Head or Tail area; possibly such as DNA strand breaks. Moreover, to challenge during-learning irradiation, we attempt the development of live-targeting system for non-paralyzed using the micro-device. We will discuss on the new approach.