Refine your search�ソスF     
Report No.

Carbon-ion microbeam induces behavioral change in the salt chemotaxis learning of ${it C. elegans}$

Sakashita, Tetsuya; Suzuki, Michiyo; Muto, Yasuko; Yokota, Yuichiro; Funayama, Tomoo; Hamada, Nobuyuki*; Fukamoto, Kana*; Kobayashi, Yasuhiko

To investigate the effects on the neuronal tissue (a nerve ring), we used the heavy-ion microbeam system. Well-fed adults of ${it C. elegans}$ grown on the plate spread with the ${it E. coli OP50}$ were used in all experiments. Anesthetized animals were irradiated locally with carbon-ion microbeams that were extracted into the air through an aperture. Immediately after microbeam irradiation, chemotaxis to NaCl of exposed animals was measured. Microbeam irradiation experiments in the both areas showed no significant effects on the ability of the salt chemotaxis learning. It indicates that the salt chemotaxis learning in ${it C. elegans}$ is not affected by carbon-ion induced damage in Head or Tail area; possibly such as DNA strand breaks. Moreover, to challenge during-learning irradiation, we attempt the development of live-targeting system for non-paralyzed ${it C.elegans}$ using the micro-device. We will discuss on the new approach.



- Accesses





[CLARIVATE ANALYTICS], [WEB OF SCIENCE], [HIGHLY CITED PAPER & CUP LOGO] and [HOT PAPER & FIRE LOGO] are trademarks of Clarivate Analytics, and/or its affiliated company or companies, and used herein by permission and/or license.