Spectroscopic study of radiation-induced DNA lesions and their susceptibility to enzymatic repair

Yokoya, Akinari; Fujii, Kentaro; Shikazono, Naoya; Ukai, Masatoshi*

This review is one of the chapters of "Charged Particle and Photon Interactions with Matter; Recent Advances, Applications, and Interfaces". In this review we will introduce recent advances in spectroscopic study of DNA damage induced by ionizing radiation using synchrotron radiation and ion particles. Further, studies of susceptibility of DNA damage to enzymatic repair-processes revealed by biochemical techniques, as well as mutation assay for E. coli cells, will also be described and discussed by comparing with previous simulation data.

Language	:	English
Journal	:	Charged Particle and Photon Interactions with Matter; Recent Advances, Applications, and Interfaces
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Pages	:	p.543 - 574
Publication Year/Month	:	2010/12
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Registration No. : AA20100375
JAEA Abstracts No. : 39000241
Paper Submission No. : 8475

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