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Cocktail beam acceleration technique for quick change of microbeam at the JAEA AVF cyclotron

Kurashima, Satoshi; Yoshida, Kenichi; Sato, Takahiro; Miyawaki, Nobumasa; Kashiwagi, Hirotsugu; Okumura, Susumu; Kamiya, Tomihiro; Yokota, Wataru

A heavy-ion microbeam is provided for the TIBIC experiment and living-cell irradiation in biotechnology at the JAEA AVF cyclotron facility. A microbeam of 260-MeV $$^{20}$$Ne$$^{7+}$$ with a spot size less than 1 $$mu$$m in diameter is formed using a flat-top acceleration system. Users of the microbeam need a wide range of linear energy transfer (LET), and the ion species and/or energy have to be changed in order to vary LET. However, it takes a few hours to tune the cyclotron for the microbeam formation so that a microbeam of one species is usually provided in one beam time. A cocktail beam acceleration technique has been adopted to change the ion species quickly. In this technique, ion species having almost the same mass to charge ratio (M/Q) are injected into the cyclotron simultaneously, and only one ion species whose cyclotron resonance frequency is equal to the acceleration frequency is extracted from the cyclotron. Another species is extracted by slightly shifting the acceleration frequency. The magnetic rigidity of extracted beams is the same, therefore, lens parameters of the beam transport line are not required to be changed basically. Quick change of ion species of microbeam from 260-MeV $$^{20}$$Ne$$^{7+}$$ to 520-MeV $$^{40}$$Ar$$^{14+}$$ was examined for a cocktail with M/Q = 2.85 and successfully performed within 30 minutes.

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