Study of supra-additive effect by cisplatin association and X-ray irradiation on the DNA damage in base level

Igarashi, Shosuke*; Onuki, Toshihiko; Sakamoto, Fuminori ; Tachibana, Akira*

Effects of radiation on the cisplatin associated DNA have been studied in base level by using Sanger method. The results indicated that presence of cisplatin enhanced strand break by X-ray irradiation, and positions of the strand break bases are related to the association of cisplatin with bases.

Language	:	Japanese
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Meeting title	:	日本放射線影響学会第54回大会
Held date	:	2011/11
Location (city)	:	神戸
Location (country)	:	日本
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Keywords	:	no keyword
Research Facility	:	第4研究棟
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Registration No. : BB20112328
JAEA Abstracts No. :
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