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Report No.
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Technical development for the production of radiopharmaceutical molybdenum

Tanimoto, Masataka ; Tsuchiya, Kunihiko 

$$^{99m}$$Tc is most commonly used as a radiopharmaceutical in the field of nuclear medicine, accounting for more than 80% of all diagnostic nuclear medicine procedure. The $$^{99m}$$Tc is obtained from $$^{99}$$Mo, which is produced by fission of $$^{235}$$U ((n, f) method) and the neutron capture (n,$$gamma$$) method using the $$^{98}$$Mo target. Recently, worldwide demand of $$^{99}$$Mo became rises. However the availability and supply of $$^{99}$$Mo for the manufacturing of generators has been a matter of concern. Concern arose from several factors including, such as the shutdown of some nuclear reactors at Canada (NRU, etc.) and Air traffic obstacles, uncertainty of reliable operating condition for radioisotope production in the majority of the foreign production facilities. This report provides descriptions for the detail technical aspects related to a $$^{99}$$Mo production by (n,$$gamma$$) method in JMTR.

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