Refine your search�ソスF     
Report No.

Behavioral resistance of ${it Caenorhabditis elegans}$ against high-LET radiation exposure

Sakashita, Tetsuya; Suzuki, Michiyo; Hamada, Nobuyuki*; Shimozawa, Yoko; Fukamoto, Kana*; Yokota, Yuichiro; Sora, Sakura*; Kakizaki, Takehiko*; Wada, Seiichi*; Funayama, Tomoo; Kobayashi, Yasuhiko

Here, we investigated the resistance to high-LET radiation exposure for two behaviors of the nematode, ${it Caenorhabditis elegans}$, which is known as a model organism for the nervous system. Tested behaviors were locomotion and chemotaxis to NaCl. In addition, egg hatchability was examined as an indicator of high-LET radiation sensitivity. Relative biological effectiveness (RBE) of high-LET radiation ($$^{12}$$C, 18.3 MeV/u, LET = 113 keV/$$mu$$m) relative to low-LET radiation for hatchability was 4.5, whereas RBEs for locomotion and chemotaxis were 1.4 and 1.1, respectively. This study shows that the behavioral system for locomotion and chemotaxis of ${it C. elegans}$ is highly resistant to high-LET radiation exposure.



- Accesses





[CLARIVATE ANALYTICS], [WEB OF SCIENCE], [HIGHLY CITED PAPER & CUP LOGO] and [HOT PAPER & FIRE LOGO] are trademarks of Clarivate Analytics, and/or its affiliated company or companies, and used herein by permission and/or license.