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Production and separation of radioactive astatine isotopes in the $$^7$$Li+$$^{nat}$$Pb reaction

Nishinaka, Ichiro; Yokoyama, Akihiko*; Washiyama, Koshin*; Amano, Ryohei*; Maeda, Eita*; Yamada, Norihiro*; Makii, Hiroyuki   ; Toyoshima, Atsushi; Watanabe, Shigeki; Ishioka, Noriko; Hashimoto, Kazuyuki

To promote utilization of a radioactive nuclide $$^{211}$$At which draws increasing attention as a promissing $$alpha$$-emitter for targeted alpha therapy, we have measured production cross sections of astatine isotopes in the 29-57 MeV$$^7$$Li+$$^{nat}$$Pb reaction using the tandem accelerator of JAEA-Tokai, providing nuclear data for production. For pharmaceutical study and so on, beside, we have developed a new separation procedure based on a dry-distillation method which separates carrier free astatine isotopes from lead targets with high radiochemical and chemical purity and high yields.

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