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Characterization of microbeam fields and broadbeam fields in the same framework using microdosimetric probability density

Sato, Tatsuhiko   ; Hamada, Nobuyuki*; Sakashita, Tetsuya

It is difficult to quantitatively compare between the results obtained from broadbeam and microbeam experiments because of the difference of physical indexes for characterizing their radiation fields. We therefore developed a new method for calculating the microdosimetric PD for any radiation fields, utilizing the microdosimetric function of the PHITS code. A new model assembly was then established for estimating the cell surviving fraction based on the calculated microdosimetric probability density (PD), considering both targeted and nontargeted effects in the same framework. The model assembly reproduced very well the experimentally determined surviving fraction measured with microbeam or broadbeam of energetic heavy ions as well as X-ray microbeam. The features of the established models together with the possible role of nontargeted effect in broadbeam fields will be discussed at the meeting.

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