Measurements of radon concentration in mouse blood following radon inhalation

Ishimori, Yuu  ; Tanaka, Hiroshi ; Sakoda, Akihiro   ; Kataoka, Takahiro*; Yamaoka, Kiyonori*; Mitsunobu, Fumihiro*

Various biological responses following radon inhalation are widely known. However, it is few that the responses are discussed quantitatively in relation to absorbed dose due to radon inhaled because experimental data of biokinetics of radon inhaled seem not to be many. To examine biokinetics of radon inhaled, radon concentration in mouse blood was measured after the inhalation of radon with about 1 MBq/ for several to 1000 minutes. Blood was collected from a mouse heart, and radon concentration in blood was determined by a liquid scintillation counter. This was based on the measurement technique used by JAEA for radon in water. The data were corrected taking into account quenching of scintillation. As the result, radon concentration in mouse blood was 0.4160.014 Bq/g in the condition saturated with 1 MBq/m of radon concentration in the air. The time variation of radon concentration in mouse blood in the condition unsaturated was well expressed by our mathematical model.