Responses of the salt chemotaxis learning in wild type and mutant to microbeam irradiation

Sakashita, Tetsuya; Suzuki, Michiyo; Hattori, Yuya; Ikeda, Hiroko; Muto, Yasuko*; Yokota, Yuichiro; Funayama, Tomoo; Hamada, Nobuyuki*; Shirai, Kana*; Kobayashi, Yasuhiko

We applied the microbeam irradiation of the central nervous tissue in to analyze direct radiation effects at a tissue level. Also, to investigate the mechanism of modulatory effects of irradiation on the salt chemotaxis learnign (SCL), we used two mutants ( and ) related to the SCL. Well-fed adults of wild-type and mutant were irradiated with 12,000 carbon ion particles corresponding to 500 Gy at micro-aperture area. Immediately after microbeam irradiation, the SCL performance was examined based on the chemotaxis index (CI). CI during the SCL was decreased in the wild-type and mutant animals, but microbeam irradiation did not significantly affect CIs of mutants. The difference of the SCL between and mutants will be discussed at the meeting.