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Production of $$^{211}$$At for alpha radiotherapy via $$^{209}$$Bi($$^7$$Li,5n)$$^{211}$$Rn

Nishinaka, Ichiro; Washiyama, Koshin*; Yokoyama, Akihiko*; Maeda, Eita*; Hashimoto, Kazuyuki; Makii, Hiroyuki   

A $$^{211}$$Rn/$$^{211}$$At generator has been proposed to supply a radiotracer $$^{211}$$At with a half-life (T$$_{1/2}$$ = 7.2 h) for medical applications. To establish a technology of the $$^{211}$$Rn/$$^{211}$$At generator, $$^{211}$$Rn (T$$_{1/2}$$ = 14.7 h) has to be produced through the $$^{209}$$Bi($$^7$$Li, 5n)$$^{211}$$Rn reaction without melting bismuth metal targets due to heat produced by the irradiation of 60 MeV $$^7$$Li ion beams. In this work, we have studied the effects of a He gas cooling system of an irradiation chamber constructed for the production of $$^{211}$$Rn. Irradiations were carried out at the JAEA tandem accelerator using the irradiation chamber equipped with the He gas cooling system. The results show that the He gas effectively cools the targets and the cooling efficiency is nearly independent of the pressure ($$>$$ 1 kPa) and the flow rate ($$sim$$20 L/min) of the He gas.

Language

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Japanese

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Volume

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Number

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Publication Year/Month

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Meeting title

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2015日本放射化学会年会・第59回放射化学討論会

Held date

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2015/09

Location (city)

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仙台

Location (country)

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日本

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Paper URL

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DOI for research data

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Keywords

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アルファ線; アスタチン211; ラドン211; ジェネレータ

Research Facility

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タンデム加速器  

Press Release

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Article of JAEA R&D Review

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Cooperating Institute

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金沢大学

Accesses

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- Accesses

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