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Report No.

Improvement of a metabolic model for iodine and consideration of a equivalent dose to the thyroid reduction factor for application to the OSCAAR code

Kimura, Masanori ; Hato, Shinji*; Matsubara, Takeshi*; Kanno, Mitsuhiro*; Munakata, Masahiro 

The authors developed a new metabolic model for iodine by combining the respiratory tract model (Publ.66), the gastrointestinal tract model (Publ.30) of the ICRP and the metabolic model for iodine (Johnson's model) in order to evaluate the behavior of radioiodine and stable iodine in the body more realistically. The developed metabolic model indicated that a reduction factor (RF) depends on dosage of stable iodine, timing of the administration of stable iodine, different iodine isotopes ($$^{131}$$I - $$^{135}$$I), and age groups. Therefore, the RF was calculated by changing these parameters and then a database of the RF was constructed for the application to the OSCAAR code.



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