Overview of computational mouse models

マウスモデルの概説

Mohammadi, A.*; 木名瀬 栄   ; Safavi-Naeini, M.*

Mohammadi, A.*; Kinase, Sakae; Safavi-Naeini, M.*

The review summarizes the history of development of the computational models during the last 24 years with some provision about what to expect in the near future for their application in preclinical research, radiation dosimetry calculations and imaging physics research. Around 26 computational mouse models have been constructed for various researches in ionizing and nonionizing radiation dosimetry, preclinical imaging including multimodality imaging and instrumentation, image processing and analysis. The approach of using the computational mouse models and simulation tools are very useful comparing the experimental approach using physical phantoms or real mice due to high cost and complexity of organizing an experimental research.