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The Study of oxidative stress status in the organs exposed to low dose/low dose-rate radiation (Contract research); FY2020 Nuclear Energy Science & Technology and Human Resource Development Project

Collaborative Laboratories for Advanced Decommissioning Science; Tohoku University*

The Collaborative Laboratories for Advanced Decommissioning Science (CLADS), Japan Atomic Energy Agency (JAEA), had been conducting the Nuclear Energy Science & Technology and Human Resource Development Project (hereafter referred to "the Project") in FY2020. The Project aims to contribute to solving problems in the nuclear energy field represented by the decommissioning of the Fukushima Daiichi Nuclear Power Station, Tokyo Electric Power Company Holdings, Inc. (TEPCO). For this purpose, intelligence was collected from all over the world, and basic research and human resource development were promoted by closely integrating/collaborating knowledge and experiences in various fields beyond the barrier of conventional organizations and research fields. The sponsor of the Project was moved from the Ministry of Education, Culture, Sports, Science and Technology to JAEA since the newly adopted proposals in FY2018. On this occasion, JAEA constructed a new research system where JAEA-academia collaboration is reinforced and medium-to-long term research/development and human resource development contributing to the decommissioning are stably and consecutively implemented. Among the adopted proposals in FY2019, this report summarizes the research results of the "The study of oxidative stress status in the organs exposed to low dose/low dose-rate radiation" conducted in FY2020. The present study aims to investigate the biological effects of low dose/low dose-rate radiation exposure, which is of great social interest, on the oxidative stress status of individual organs and will contribute to the collection of scientific data in a dose range to be required. An interdisciplinary collaborative study discussed the correlation between radiation dose and the biological effect by analyzing the samples of wild Japanese macaques exposed to radiation due to the accident of Fukushima Daiichi Nuclear Power Station and of animal experiments.

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