Refine your search�ソスF     
Report No.

Development of the DICOM-based Monte Carlo dose reconstruction system for a retrospective study on the secondary cancer risk in carbon ion radiotherapy

Furuta, Takuya   ; Koba, Yusuke*; Hashimoto, Shintaro  ; Chang, W.*; Yonai, Shunsuke*; Matsumoto, Shinnosuke*; Ishikawa, Akihisa*; Sato, Tatsuhiko   

Carbon ion radiotherapy has an advantage over conventional radiotherapy such that its superior dose concentration on the tumor helps to reduce unwanted dose to surrounding normal tissues. Nevertheless, a little dose to normal tissues, which is a potential risk of secondary cancer, is still unavoidable. The Monte Carlo simulation is a good candidate for the tool to assess secondary cancer risk, including the contributions of secondary particles produced by nuclear reactions. We therefore developed a new dose reconstruction system implementing PHITS as the engine. In this system, the PHITS input is automatically created from the DICOM data sets recorded in the treatment planning. The developed system was validated by comparing to experimental dose distribution in water and treatment plan on an anthropomorphic phantom. This system will be used for retrospective studies using the patient data in National Institute for Quantum and Science and Technology.



- Accesses




Category:Engineering, Biomedical



[CLARIVATE ANALYTICS], [WEB OF SCIENCE], [HIGHLY CITED PAPER & CUP LOGO] and [HOT PAPER & FIRE LOGO] are trademarks of Clarivate Analytics, and/or its affiliated company or companies, and used herein by permission and/or license.