Consideration of the production method for Auger electron emitter Br using the CCONE-based calculation system

Sakai, Seiya*; Otsu, Hideaki*; Iwamoto, Osamu  ; Iwamoto, Nobuyuki  ; Nakayama, Shinsuke  ; Fukahori, Tokio  ; Kikunaga, Hidetoshi*; Yokokita, Takuya*

Recently, nuclear medicine therapy using nuclides emitting rays and Auger electrons has attracted attention. In particular, the SEKIGUCHI Three-Nucleon Force Project aims to realize nuclear medicine therapy using the Auger electron emitter Br. Br has a half-life of 2.38 days and is readily available for medical use. In addition, Br is a Group 17 (halogen) element, like At, which is in rapidly increasing demand as an ray emitter for nuclear medicine therapy, and its similar chemical properties are useful in understanding the differences in biological effects between rays and Auger electrons. However, the reactions and pathways for the production of Br are diverse and the optimal production method has not yet been established. Therefore, we considered the optimal production method for Br using the CCONE-based calculation system in terms of thick target yields by injection of neutron, proton, deuteron, alpha-particle and gamma-ray up to 50 MeV.