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Endo, Akira
Isotope News, (781), P. 3, 2022/06
The research reactor JRR-3 at the Nuclear Science Research Institute of Japan Atomic Energy Agency resumed its operation in February 2021 for the first time in 10 years. After commissioning, neutron beam experimental apparatus and irradiation facilities were used from July to November, and the operation in 2021 was completed as planned. During this period, Ir-192 and Au-198 were produced and supplied for therapeutic use, and test irradiation for the production of Mo-99 was performed. This is resumption of radioisotope production using nuclear reactors in Japan, which had stopped after the Great East Japan Earthquake. This article introduces future efforts of radioisotope production for medical applications in JRR-3.
Cu and 
Cu via the Zn(n, p)Cu and 
Zn(n, np/d)Cu reactions using accelerator neutronsKawabata, Masako*; Motoishi, Shoji*; Ota, Akio*; Motomura, Arata*; Saeki, Hideya*; Tsukada, Kazuaki; Hashimoto, Shintaro; Iwamoto, Nobuyuki; Nagai, Yasuki*; Hashimoto, Kazuyuki*
Journal of Radioanalytical and Nuclear Chemistry, 330(3), p.913 - 922, 2021/12
Times Cited Count：7 Percentile：75.12(Chemistry, Analytical)Both Cu and Cu are promising radionuclides in nuclear medicine. Production yields of these radionuclides were quantified by irradiating 55.4 g of natural zinc with accelerator neutrons. Clinically suitable Cu and Cu yields were estimated by experimental based numerical simulations using 100 g of enriched Zn and Zn, respectively, and elevated neutron fluxes from 40 MeV, 2 mA deuterons. A combined thermal- and resin-separation method was developed to isolate Cu and Cu from zinc, resulting in 73% separation efficiency and 97% zinc recovery. Such methods can provide large scale production of Cu and Cu for clinical applications.
Benu, D. P.*; Earnshaw, J.*; Ashok, A.*; Tsuchiya, Kunihiko; Saptiama, I.*; Yuliarto, B.*; Suendo, V.*; Mukti, R. R.*; Fukumitsu, Nobuyoshi*; Ariga, Katsuhiko*; et al.
Bulletin of the Chemical Society of Japan, 94(2), p.502 - 507, 2021/02
Times Cited Count：11 Percentile：64.63(Chemistry, Multidisciplinary)no abstracts in English
Mo yield using large sample mass of MoO
for sustainable production of MoTsukada, Kazuaki; Nagai, Yasuki*; Hashimoto, Kazuyuki*; Kawabata, Masako*; Minato, Futoshi; Saeki, Hideya*; Motoishi, Shoji*; Ito, Masatoshi*
Journal of the Physical Society of Japan, 87(4), p.043201_1 - 043201_5, 2018/04
Times Cited Count：10 Percentile：59.63(Physics, Multidisciplinary)Cu suitable for both cancer diagnosis and therapyNagai, Yasuki*; Tsukada, Kazuaki
Isotope News, (753), p.28 - 32, 2017/10
no abstracts in English
Watanabe, Yukinobu*; Kin, Tadahiro*; Araki, Shohei*; Nakayama, Shinsuke; Iwamoto, Osamu
EPJ Web of Conferences, 146, p.03006_1 - 03006_6, 2017/09
Times Cited Count：2 Percentile：77.79(Nuclear Science & Technology)The design of 
neutron sources requires comprehensive nuclear data of deuteron-induced reactions. Therefore, we have launched a research project on deuteron nuclear data, which is composed of measurements, theoretical model code development, cross section evaluation, and application to production of radioisotopes for medical use. Our goal is to develop a state-of-art deuteron nuclear data library up to 200 MeV necessary for the design of accelerator neutron sources with deuteron beam. The present status is reported in the presentation.
Cu produced by Zn(
)Cu to biodistribution study in tumor-bearing miceSugo, Yumi*; Hashimoto, Kazuyuki*; Kawabata, Masako*; Saeki, Hideya*; Sato, Shunichi*; Tsukada, Kazuaki; Nagai, Yasuki*
Journal of the Physical Society of Japan, 86(2), p.023201_1 - 023201_3, 2017/02
Times Cited Count：14 Percentile：67.59(Physics, Multidisciplinary)Cu produced by the Zn()Cu reaction was used for the first time to determine the biodistribution of CuCl
in colorectal tumor-bearing mice. High uptake of Cu was observed in the tumor as well as in the liver and kidney which are the major organs for copper metabolism. The result showing Cu accumulation in the tumor suggests that CuCl can be a potential radionuclide agent for cancer radiotherapy. It would also encourage further studies on the therapeutic effect in small animals using an increased dose of Cu produced by the Zn()Cu reaction using intense neutrons available at present.
Proc. of Korea Atomic Industrial Forum,Inc., p.347 - 357, 1997/04
no abstracts in English
Isotope News, 0(483), p.38 - 39, 1994/09
no abstracts in English
Ir brachytherapy wiresD.F.G.Reher*; A.H.L.Aalbers*; H.Bjerke*; N.Drugge*; Genka, Tsuguo; M.J.Rossiter*; D.Santry*; J.P.Sephton*; G.Sibbens*; J.Seuntjens*; et al.
Nuclear Instruments and Methods in Physics Research A, 339, p.386 - 390, 1994/00
Times Cited Count：5 Percentile：53.31(Instruments & Instrumentation)no abstracts in English
Yoshii, Fumio
J. Radiat. Steril., 1, p.171 - 194, 1993/00
no abstracts in English
Yoshii, Fumio
Ika Kikaigaku, 62(2), p.78 - 86, 1992/02
no abstracts in English
Ishigaki, Isao; Yoshii, Fumio
Radiation Physics and Chemistry, 39(6), p.527 - 533, 1992/00
no abstracts in English
Genka, Tsuguo
Radioisotopes, 41(8), p.61 - 62, 1992/00
no abstracts in English
Ito, Hitoshi
Ika Kikaigaku, 60(10), p.469 - 475, 1990/10
no abstracts in English
Makuuchi, Keizo
Isotope News, 0(2), p.10 - 12, 1990/02
no abstracts in English
Yoshii, Fumio
Hoshasen Kagaku, 0(48), p.34 - 37, 1989/00
no abstracts in English
Z.A.Kadir*; Yoshii, Fumio; Makuuchi, Keizo; Ishigaki, Isao
Polymer, 30, p.1425 - 1432, 1989/00
Times Cited Count：22 Percentile：72.31(Polymer Science)no abstracts in English
;
Hoshasen To Sangyo, 32, p.15 - 20, 1986/00
no abstracts in English
; ; ;
J.Appl.Polym.Sci., 31, p.1343 - 1350, 1986/00
Times Cited Count：30 Percentile：81.14(Polymer Science)no abstracts in English
