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Sakamoto, Tomokazu*; Asazawa, Koichiro*; Martinez, U.*; Halevi, B.*; Suzuki, Toshiyuki*; Arai, Shigeo*; Matsumura, Daiju; Nishihata, Yasuo; Atanassov, P.*; Tanaka, Hirohisa*
Journal of Power Sources, 234, p.252 - 259, 2013/07
Times Cited Count：68 Percentile：87.04(Chemistry, Physical)Fujii, Satoshi*; Kono, Hidetoshi; Takenaka, Shigeori*; Go, Nobuhiro; Sarai, Akinori*
Nucleic Acids Research, 35(18), p.6063 - 6074, 2007/09
Times Cited Count：98 Percentile：86.53(Biochemistry & Molecular Biology)Proteins recognize specific DNA sequences not only through direct contact between amino acids and bases, but also indirectly based on the sequence-dependent conformation and deformability of the DNA (indirect readout). We used molecular dynamics simulations to analyze the sequence-dependent DNA conformations of all 136 possible tetrameric sequences sandwiched between CGCG sequences. The deformability of dimeric steps obtained by the simulations is consistent with that by the crystal structures. The simulation results further showed that the conformation and deformability of the tetramers can highly depend on the flanking base-pairs. The conformations of xATx tetramers show the most rigidity and are not affected by the flanking base-pairs and the xYRx show by contrast the greatest flexibility and change their conformations depending on the base-pairs at both ends, suggesting tetramers with the same central dimer can show different deformabilities. These results suggest that analysis of dimeric steps alone may overlook some conformational features of DNA and provide insight into the mechanism of indirect readout during protein-DNA recognition. Moreover, the sequence dependence of DNA conformation and deformability may be used to estimate the contribution of indirect readout to the specificity of protein-DNA recognition as well as nucleosome positioning and large-scale behavior of nucleic acids.
Osaka, Masahiko; Serizawa, Hiroyuki*; Kato, Masato; Inoue, Masaki; Nakajima, Kunihisa*; Tachi, Yoshiaki; Kitamura, Ryoichi; Oki, Shigeo; Miwa, Shuhei; Iwai, Takashi*; et al.
Proceedings of International Conference on Nuclear Energy System for Future Generation and Global Sustainability (GLOBAL 2005) (CD-ROM), 6 Pages, 2005/10
Development of minor actinide containing fuel/target, i.e., (Pu,Am)O
-MgO, (Pu,Np)O-MgO, (U,Pu,Np)O, (U,Pu,Np)N and (Pu,Np,Zr)N, for the use in a future integrated system of fast reactor and accelerator driven system is underway as a collaborative work between JAERI and JNC. The present statuses of fabrication test and property measurements are given. Irradiation test in the experimental fast reactor JOYO is also mentioned.
Fujii, Satoshi*; Ara
zo-Bravo, M. J.*; Takenaka, Shigeori*; Kono, Hidetoshi; Go, Nobuhiro; Sarai, Akinori*
no journal, ,
no abstracts in English
Fujii, Satoshi*; Kono, Hidetoshi; Takenaka, Shigeori*; Go, Nobuhiro; Sarai, Akinori*
no journal, ,
no abstracts in English
Fujii, Satoshi*; Kono, Hidetoshi; Takenaka, Shigeori*; Go, Nobuhiro; Sarai, Akinori*
no journal, ,
no abstracts in English
-ray irradiation on electrical characteristics of SiC schottky barrier diodeKinoshita, Akimasa*; Tanaka, Yasunori*; Tanaka, Tomoyuki*; Fukuda, Kenji*; Arai, Kazuo*; Oshima, Takeshi; Hishiki, Shigeomi
no journal, ,
no abstracts in English
Fujii, Satoshi*; Kono, Hidetoshi; Takenaka, Shigeori*; Go, Nobuhiro; Sarai, Akinori*
no journal, ,
no abstracts in English
Miyazaki, Yasunori; Sano, Yuichi; Takeuchi, Masayuki; Arai, Tsuyoshi*; Kim, S.-Y.*; Wu, H.*; Miwa, Misako*; Matsuyama, Shigeo*
no journal, ,
Separation of minor actinides (MA; Am, Cm) is social demand to reduce the volume and toxicity of radioactive waste generated by spent nuclear fuel reprocessing. We have proposed extraction chromatography that employs the TEHDGA-impregnated adsorbent in a separation column. From the previous study, MA recovery from the real radioactive waste liquid was achieved, and a flowsheet study is continued to improve the product purity (or decontamination coefficient). On the other hand, we are also investigating the decomposition and reuse of spent adsorbent. In this presentation, both of the degradability of the adsorbent by the Fenton reaction and the reusability of the re-impregnated adsorbent from the batch-wise adsorption test results are reported by the element distribution by micro-PIXE analysis.
