Schuemann, J.*; McNamara, A. L.*; Warmenhoven, J. W.*; Henthorn, N. T.*; Kirkby, K.*; Merchant, M. J.*; Ingram, S.*; Paganetti, H.*; Held, K. D.*; Ramos-Mendez, J.*; et al.
Radiation Research, 191(1), p.76 - 93, 2019/01
We propose a new Standard DNA Damage (SDD) data format to unify the interface between the simulation of damage induction in DNA and the biological modelling of DNA repair processes, and introduce the effect of the environment (molecular oxygen or other compounds) as a flexible parameter. Such a standard greatly facilitates inter-model comparisons, providing an ideal environment to tease out model assumptions and identify persistent, underlying mechanisms. Through inter-model comparisons, this unified standard has the potential to greatly advance our understanding of the underlying mechanisms of radiation-induced DNA damage and the resulting observable biological effects when radiation parameters and/or environmental conditions change.
Chadwick, M. B.*; Capote, R.*; Trkov, A.*; Herman, M. W.*; Brown, D. A.*; Hale, G. M.*; Kahler, A. C.*; Talou, P.*; Plompen, A. J.*; Schillebeeckx, P.*; et al.
Nuclear Data Sheets, 148, p.189 - 213, 2018/02
The CIELO collaboration has studied neutron cross sections on nuclides that significantly impact criticality in nuclear facilities - U, U, Pu, Fe, O and H - with the aim of improving the accuracy of the data and resolving previous discrepancies in our understanding. This multi-laboratory pilot project, coordinated via the OECD/NEA Working Party on Evaluation Cooperation (WPEC) Subgroup 40 with support also from the IAEA, has motivated experimental and theoretical work and led to suites of new evaluated libraries that accurately reflect measured data and also perform well in integral simulations of criticality. This report summarizes our results and outlines plans for the next phase of this collaboration.
Chadwick, M. B.*; Capote, R.*; Trkov, A.*; Kahler, A. C.*; Herman, M. W.*; Brown, D. A.*; Hale, G. M.*; Pigni, M.*; Dunn, M.*; Leal, L.*; et al.
EPJ Web of Conferences (Internet), 146, p.02001_1 - 02001_9, 2017/09
The CIELO collaboration has studied neutron cross sections on nuclides (O, Fe, U and Pu) that significantly impact criticality in nuclear technologies with the aim of improving the accuracy of the data and resolving previous discrepancies in our understanding. This multi-laboratory pilot project, coordinated via the OECD/NEA Working Party on Evaluation Cooperation (WPEC) Subgroup 40 with support also from the IAEA, has motivated experimental and theoretical work and led to suites of new evaluated libraries that accurately reflect measured data and also perform well in integral simulations of criticality.
Carlson, A. D.*; Pronyaev, V.*; Hale, G. M.*; Zhenpeng, C.*; Capote, R.*; Durn, I.*; Hambsch, F.-J.*; Kawano, Toshihiko*; Kunieda, Satoshi; 13 of others*
EPJ Web of Conferences (Internet), 146, p.02025_1 - 02025_4, 2017/09
Evaluations are being done for the H(n,n), Li(n,t), B(n,), B(n,), C(n,n), Au(n,), U(n,f) and U(n,f) standard cross sections. Evaluations are also being done for data that are not traditional standards including: the Au(n,) cross section at energies below where it is considered a standard; reference cross sections for prompt -ray production in fast neutron-induced reactions; reference cross sections for very high energy fission cross sections; the U thermal neutron fission spectrum and the Cf spontaneous fission neutron spectrum and the thermal constants.
Chakraborty, S.*; Datta, U.*; Aumann, T.*; Beceiro-Novo, S.*; Boretzky, K.*; Caesar, C.*; Carlson, B. V.*; Catford, W. N.*; Chartier, M.*; Cortina-Gil, D.*; et al.
Physical Review C, 96(3), p.034301_1 - 034301_9, 2017/09
no abstracts in English
Polster, L.*; Schuemann, J.*; Rinaldi, I.*; Burigo, L.*; McNamara, A. L.*; Steward, R. D.*; Attili, A.*; Carlson, D. J.*; Sato, Tatsuhiko; Ramos Mndez, J.*; et al.
Physics in Medicine and Biology, 60(13), p.5053 - 5070, 2015/07
The aim of this work is to extend a widely used proton Monte Carlo tool, TOPAS, towards the modeling of relative biological effect (RBE) distributions in experimental arrangements as well as patients. Then, eight biophysical models was incorporated into TOPAS. As far as physics parameters are concerned, four of these models are based on the proton linear energy transfer (LET), while the others are based on DNA Double Strand Break (DSB) induction and the frequency-mean specific energy, lineal energy, or delta electron generated track structure. The model on the basis of lineal energy adapted a microdosimetric function developed by JAEA. This work is an important step in bringing biologically optimized treatment planning for proton therapy closer to the clinical practice.
Chadwick, M. B.*; Dupont, E.*; Bauge, E.*; Blokhin, A.*; Bouland, O.*; Brown, D. A.*; Capote, R.*; Carlson, A. D.*; Danon, Y.*; De Saint Jean, C.*; et al.
Nuclear Data Sheets, 118, p.1 - 25, 2014/04
CIELO (Collaborative International Evaluated Library Organization) provides a new working paradigm to facilitate evaluated nuclear reaction data advances. It brings together experts from across the international nuclear reaction data community to identify and document discrepancies among existing evaluated data libraries, measured data, and model calculation interpretations, and aims to make progress in reconciling these discrepancies to create more accurate ENDF-formatted files. The focus will initially be on a small number of the highest-priority isotopes, namely H, O, Fe, U, and Pu. This paper identifies discrepancies between various evaluations of the highest priority isotopes. The evaluated data for these materials in the existing nuclear data libraries are reviewed, and some integral properties are given. The paper summarizes a program of nuclear science and computational work needed to create the new CIELO nuclear data evaluations.
Chadwick, M. B.*; Herman, M.*; Obloinsk, P.*; Dunn, M. E.*; Danon, Y.*; Kahler, A. C.*; Smith, D. L.*; Pritychenko, B.*; Arbanas, G.*; Arcilla, R.*; et al.
Nuclear Data Sheets, 112(12), p.2887 - 2996, 2011/12
The ENDF/B-VII.1 library is our latest recommended evaluated nuclear data file for use in nuclear science and technology applications, and incorporates advances made in the five years since the release of ENDF/B-VII.0. These advances focus on neutron cross sections, covariances, fission product yields and decay data, and represent work by the US Cross Section Evaluation Working Group (CSEWG) in nuclear data evaluation that utilizes developments in nuclear theory, modeling, simulation, and experiment. It features extension of covered nuclei, covariance data for 190 nuclei, R-matrix analyses of neutron reactions on light nuclei, updates for some medium-heavy and actinoid nuclei, etc. Criticality benchmark tests with a transport simulation code MCNP shows improved performances.
Kawano, Toshihiko*; Carlson, A. D.*; Matsunobu, Hiroyuki*; Nakagawa, Tsuneo; Shibata, Keiichi; Talou, P.*; Young, P. G.*; Chadwick, M. B.*
JAERI-Research 2001-058, 28 Pages, 2002/01
no abstracts in English
Glugla, M.*; Beloglazov, S.*; Carlson, B.*; Cho, S.*; Cristescu, I.*; Cristecu, I.*; Chung, H.*; Girard, J.-P.*; Hayashi, Takumi; Mardoch, D.*; et al.
no journal, ,