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Journal Articles

PARaDIM; A PHITS-based Monte Carlo tool for internal dosimetry with tetrahedral mesh computational phantoms

Carter, L. M.*; Crawford, T. M.*; Sato, Tatsuhiko; Furuta, Takuya; Choi, C.*; Kim, C. H.*; Brown, J. L.*; Bolch, W. E.*; Zanzonico, P. B.*; Lewis, J. S.*

Journal of Nuclear Medicine, 60(12), p.1802 - 1811, 2019/12

 Times Cited Count:1 Percentile:100(Radiology, Nuclear Medicine & Medical Imaging)

Voxel human phantoms have been used for internal dose assessment. More anatomically accurate representation become possible for skins or layer tissues owing to recent developments of advanced polygonal mesh-type phantoms and thus internal dose assessment using those advanced phantoms are desired. However, the Monte Carlo transport calculation by implementing those phantoms require an advanced knowledge for the Monte Carlo transport codes and it is only limited to experts. We therefore developed a tool, PARaDIM, which enables users to conduct internal dose calculation with PHITS easily by themselves. With this tool, a user can select tetrahedral-mesh phantoms, set radionuclides in organs, and execute radiation transport calculation with PHITS. Several test cases of internal dosimetry calculations were presented and usefulness of this tool was demonstrated.

Journal Articles

Passive sweat collection and colorimetric analysis of biomarkers relevant to kidney disorders using a soft microfluidic system

Zhang, Y.*; Guo, H.*; Kim, S. B.*; Wu, Y.*; Ostojich, D.*; Park, S. H.*; Wang, X.*; Weng, Z.*; Li, R.*; Bandodkar, A. J.*; et al.

Lab on a Chip, 19(9), p.1545 - 1555, 2019/05

 Times Cited Count:11 Percentile:1.69(Biochemical Research Methods)

This paper introduces two important advances in recently reported classes of soft, skin-interfaced microfluidic systems for sweat capture and analysis: (1) a simple, broadly applicable means for collection of sweat that bypasses requirements for physical/mental exertion or pharmacological stimulation and (2) a set of enzymatic chemistries and colorimetric readout approaches for determining the concentrations of creatinine and urea in sweat, across physiologically relevant ranges. The results allow for routine, non-pharmacological capture of sweat across patient populations, such as infants and the elderly, that cannot be expected to sweat through exercise, and they create potential opportunities in the use of sweat for kidney disease screening/monitoring.

Journal Articles

$$^{239}$$Pu nuclear magnetic resonance in the candidate topological insulator PuB$$_4$$

Dioguardi, A. P.*; Yasuoka, Hiroshi*; Thomas, S. M.*; Sakai, Hironori; Cary, S. K.*; Kozimor, S. A.*; Albrecht-Schmitt, T. E.*; Choi, H. C.*; Zhu, J.-X.*; Thompson, J. D.*; et al.

Physical Review B, 99(3), p.035104_1 - 035104_6, 2019/01

 Times Cited Count:0 Percentile:100(Materials Science, Multidisciplinary)

We present a detailed nuclear magnetic resonance (NMR) study of $$^{239}$$Pu in bulk and powdered single-crystal plutonium tetraboride (PuB$$_4$$), which has recently been investigated as a potential correlated topological insulator. The $$^{239}$$Pu NMR spectra are consistent with axial symmetry of the shift tensor showing for the first time that $$^{239}$$Pu NMR can be observed in an anisotropic environment and up to room temperature. The temperature dependence of the $$^{239}$$Pu shift, combined with a relatively long spin-lattice relaxation time ($$T_1$$), indicate that PuB$$_4$$ adopts a nonmagnetic state with gaplike behavior consistent with our density functional theory calculations. The temperature dependencies of the NMR Knight shift and $$T^{-1}$$ imply bulk gaplike behavior confirming that PuB$$_4$$ is a good candidate topological insulator.

Journal Articles

Battery-free, skin-interfaced microfluidic/electronic systems for simultaneous electrochemical, colorimetric, and volumetric analysis of sweat

Bandodkar, A. J.*; Gutruf, P.*; Choi, J.*; Lee, K.-H.*; Sekine, Yurina; Reeder, J. T.*; Jeang, W. J.*; Aranyosi, A. J.*; Lee, S. P.*; Model, J. B.*; et al.

Science Advances (Internet), 5(1), p.eaav3294_1 - eaav3294_15, 2019/01

 Times Cited Count:60 Percentile:0.14(Multidisciplinary Sciences)

Interest in advanced wearable technologies increasingly extends beyond systems for biophysical measurements to those that enable continuous, non-invasive monitoring of biochemical markers in biofluids. Here, we introduce battery-free, wireless microelectronic platforms that perform sensing via schemes inspired by the operation of biofuel cells. Combining these systems in a magnetically releasable manner with chrono-sampling microfluidic networks that incorporate assays based on colorimetric sensing yields thin, flexible, lightweight, skin-interfaced technologies with broad functionality in sweat analysis. A demonstration device allows simultaneous monitoring of sweat rate/loss, along with quantitative measurements of pH and of lactate, glucose and chloride concentrations using biofuel cell and colorimetric approaches.

Journal Articles

Soft, skin-interfaced microfluidic systems with wireless, battery-free electronics for digital, real-time tracking of sweat loss and electrolyte composition

Kim, S. B.*; Lee, K.-H.*; Raj, M. S.*; Reeder, J. T.*; Koo, J.*; Hourlier-Fargette, A.*; Bandodkar, A. J.*; Won, S. M.*; Sekine, Yurina; Choi, J.*; et al.

Small, 14(45), p.1802876_1 - 1802876_9, 2018/11

 Times Cited Count:16 Percentile:11.46(Chemistry, Multidisciplinary)

Excretion of sweat from eccrine glands is a dynamic physiological process that varies with body position, activity level, and health status. Information content embodied in sweat rate and chemistry can be used to assess health status and athletic performance. This paper presents a thin, miniaturized, skin-interfaced microfluidic technology that includes a reusable, battery-free electronics module for measuring sweat conductivity and rate in real-time using wireless power from and data communication with capabilities in near field communications (NFC). Systematic studies of these combined microfluidic/electronic systems, accurate correlations of measurements performed with them to those of laboratory standard instrumentation, and field tests on human subjects establish the key operational features and their utility in sweat analytics.

Journal Articles

A Fluorometric skin-interfaced microfluidic device and smartphone imaging module for ${{it in situ}}$ quantitative analysis of sweat chemistry

Sekine, Yurina; Kim, S. B.*; Zhang, Y.*; Bandodkar, A. J.*; Xu, S.*; Choi, J.*; Irie, Masahiro*; Ray, T. R.*; Kohli, P.*; Kozai, Naofumi; et al.

Lab on a Chip, 18(15), p.2178 - 2186, 2018/08

The rich composition of solutes and metabolites in sweat and its relative ease of collection upon excretion from skin pores make this class of biofluid an attractive candidate for point of care analysis. Here, we present a complementary approach that exploits fluorometric sensing modalities integrated into a soft, skin-interfaced microfluidic system which, when paired with a simple smartphone-based imaging module, allows for in-situ measurement of important biomarkers in sweat. A network array of microchannels and a collection of microreservoirs pre-filled with fluorescent probes that selectively react with target analytes in sweat (e.g. probes), enable quantitative, rapid analysis. Field studies on human subjects demonstrate the ability to measure the concentrations of chloride, sodium and zinc in sweat, with accuracy that matches that of conventional laboratory techniques.

Journal Articles

Super-absorbent polymer valves and colorimetric chemistries for time-sequenced discrete sampling and chloride analysis of sweat via skin-mounted soft microfluidics

Kim, S. B.*; Zhang, Y.*; Won, S. M.*; Bandodkar, A. J.*; Sekine, Yurina; Xue, Y.*; Koo, J.*; Harshman, S. W.*; Martin, J. A.*; Park, J. M.*; et al.

Small, 14(12), p.1703334_1 - 1703334_11, 2018/03

 Times Cited Count:26 Percentile:5.63(Chemistry, Multidisciplinary)

Journal Articles

Study on sustainable regional nuclear fuel cycle framework from nuclear non-proliferation viewpoint, 1; Historical review and basic concept to propose new framework

Kuno, Yusuke; Tazaki, Makiko; Akiba, Mitsunori*; Adachi, Takeo*; Takashima, Ryuta*; Omoto, Akira*; Oda, Takuji*; Choi, J.-S.*; Tanaka, Satoru*

Proceedings of INMM 53rd Annual Meeting (CD-ROM), 10 Pages, 2012/07

This paper will present brief historical review of multilateral nuclear approach (MNA), and based on which, a basic concept of a reliable framework of nuclear fuel cycle, where the fuel-cycle services could be provided without discrimination and meet the international 3S requirements, is discussed.

Journal Articles

Simultaneous generation of ions and high-order harmonics from thin conjugated polymer foil irradiated with ultrahigh contrast laser

Choi, I. W.*; Kim, I. J.*; Pae, K. H.*; Nam, K. H.*; Lee, C.-L.*; Yun, H.*; Kim, H. T.*; Lee, S. K.*; Yu, T. J.*; Sung, J. H.*; et al.

Applied Physics Letters, 99(18), p.181501_1 - 181501_3, 2011/11

 Times Cited Count:15 Percentile:39.39(Physics, Applied)

We report the manufacturing of a thin foil target made of conjugated polymer, and the simultaneous observation of laser accelerated ions and second harmonic radiation, when irradiated with ultrahigh-contrast laser pulse at a maximum intensity of 4$$times$$10$$^{19}$$ W/cm$$^{2}$$. Maximum proton energy of 8 MeV is achieved along the target normal direction. Strong second harmonic with over 6% energy ratio compared to fundamental is emitted along the specular direction. Two-dimensional particle-in-cell simulations confirm the simultaneous generation of protons and high-order harmonics, which demonstrates the feasibility of applications requiring particle and radiation sources at once, effectively using the same laser and target.

Journal Articles

Event structure and double helicity asymmetry in jet production from polarized $$p + p$$ collisions at $$sqrt{s}$$ = 200 GeV

Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Y.*; Al-Bataineh, H.*; Alexander, J.*; Aoki, K.*; Aphecetche, L.*; Armendariz, R.*; et al.

Physical Review D, 84(1), p.012006_1 - 012006_18, 2011/07

 Times Cited Count:22 Percentile:28.24(Astronomy & Astrophysics)

We report on the event structure and double helicity asymmetry ($$A_{LL}$$) of jet production in longitudinally polarized $$p + p$$ collisions at $$sqrt{s}$$ = 200 GeV. Photons and charged particles were measured by the PHENIX experiment. Event structure was compared with the results from PYTHIA event generator. The production rate of reconstructed jets is satisfactorily reproduced with the next-to-leading-order perturbative QCD calculation. We measured $$A_{LL}$$ = -0.0014 $$pm$$ 0.0037 at the lowest $$P_T$$ bin and -0.0181 $$pm$$ 0.0282 at the highest $$P_T$$ bin. The measured $$A_{LL}$$ is compared with the predictions that assume various $$Delta G(x)$$ distributions.

JAEA Reports

Theoretical study of rock for estimating long-term behavior; FY2009 (Contract research)

Ichikawa, Yasuaki*; Choi, J. H.*; Tanno, Takeo; Hirano, Toru*; Matsui, Hiroya

JAEA-Research 2011-007, 91 Pages, 2011/06

JAEA-Research-2011-007.pdf:8.75MB

We first surveyed the classical theories of fracture mechanics, and discussed the subcritical crack growth (SCG), which is observed under less load than the fracture toughness Kc. This SCG is a result of coupled mechanical and chemical effect. The SCG for granite was treated on this basis. We performed pressure dissolution experiments using specimens of single crystal quartz, since the dissolution reaction is engaged with a deformation and failure process of polycrystalline rock. The series of experiments were managed by a flow-through type changing temperature, pH and applied stress. Si concentrations we here measured. We first surveyed the theories of pressure solution. Then we proposed a theory of saluting velocity of quart which accounts for the effects of temperature, chemical (pH), solid pressure and pore pressure.

Journal Articles

Success story of waste water treatment by electron beams and challenges in Korean

Han, B.*; Kim, J. K.*; Kim, Y.*; Choi, J. S.*; Lee, M. J.*; Taguchi, Mitsumasa

Hoshasen To Sangyo, (130), p.20 - 23, 2011/06

no abstracts in English

Journal Articles

Identified charged hadron production in $$p + p$$ collisions at $$sqrt{s}$$ = 200 and 62.4 GeV

Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Yasuyuki*; Al-Bataineh, H.*; Alexander, J.*; Aoki, Kazuya*; Aphecetche, L.*; Armendariz, R.*; et al.

Physical Review C, 83(6), p.064903_1 - 064903_29, 2011/06

 Times Cited Count:132 Percentile:0.69(Physics, Nuclear)

Transverse momentum distributions and yields for $$pi^{pm}, K^{pm}, p$$, and $$bar{p}$$ in $$p + p$$ collisions at $$sqrt{s}$$ = 200 and 62.4 GeV at midrapidity are measured by the PHENIX experiment at the RHIC. We present the inverse slope parameter, mean transverse momentum, and yield per unit rapidity at each energy, and compare them to other measurements at different $$sqrt{s}$$ collisions. We also present the scaling properties such as $$m_T$$ and $$x_T$$ scaling and discuss the mechanism of the particle production in $$p + p$$ collisions. The measured spectra are compared to next-to-leading order perturbative QCD calculations.

Journal Articles

Azimuthal correlations of electrons from heavy-flavor decay with hadrons in $$p+p$$ and Au+Au collisions at $$sqrt{s_{NN}}$$ = 200 GeV

Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Yasuyuki*; Al-Bataineh, H.*; Alexander, J.*; Aoki, Kazuya*; Aphecetche, L.*; Aramaki, Y.*; et al.

Physical Review C, 83(4), p.044912_1 - 044912_16, 2011/04

 Times Cited Count:7 Percentile:48.69(Physics, Nuclear)

Measurements of electrons from the decay of open-heavy-flavor mesons have shown that the yields are suppressed in Au+Au collisions compared to expectations from binary-scaled $$p+p$$ collisions. Here we extend these studies to two particle correlations where one particle is an electron from the decay of a heavy flavor meson and the other is a charged hadron from either the decay of the heavy meson or from jet fragmentation. These measurements provide more detailed information about the interaction between heavy quarks and the quark-gluon matter. We find the away-side-jet shape and yield to be modified in Au+Au collisions compared to $$p+p$$ collisions.

Journal Articles

Measurement of neutral mesons in $$p$$ + $$p$$ collisions at $$sqrt{s}$$ = 200 GeV and scaling properties of hadron production

Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Y.*; Al-Bataineh, H.*; Alexander, J.*; Aoki, K.*; Aphecetche, L.*; Armendariz, R.*; et al.

Physical Review D, 83(5), p.052004_1 - 052004_26, 2011/03

 Times Cited Count:130 Percentile:1.61(Astronomy & Astrophysics)

The PHENIX experiment at RHIC has measured the invariant differential cross section for production of $$K^0_s$$, $$omega$$, $$eta'$$ and $$phi$$ mesons in $$p + p$$ collisions at $$sqrt{s}$$ = 200 GeV. The spectral shapes of all hadron transverse momentum distributions are well described by a Tsallis distribution functional form with only two parameters, $$n$$ and $$T$$, determining the high $$p_T$$ and characterizing the low $$p_T$$ regions for the spectra, respectively. The integrated invariant cross sections calculated from the fitted distributions are found to be consistent with existing measurements and with statistical model predictions.

Journal Articles

Status and result of the KSTAR upgrade for the 2010's campaign

Yang, H. L.*; Kim, Y. S.*; Park, Y. M.*; Bae, Y. S.*; Kim, H. K.*; Kim, K. M.*; Lee, K. S.*; Kim, H. T.*; Bang, E. N.*; Joung, M.*; et al.

Proceedings of 23rd IAEA Fusion Energy Conference (FEC 2010) (CD-ROM), 8 Pages, 2011/03

Because the 2010 operation of Korea Superconducting Tokamak Advanced Research (KSTAR) mainly aims to achieve strongly elongated and diverted plasma, all the necessary hardware systems to provide an essential circumstance for the plasma shaping were newly installed and upgraded in 2010. In this paper, general configuration of the upgraded systems described earlier will be outlined. Moreover, several key performances and test results of the systems will be also reported in summary.

Journal Articles

Laser-driven proton generation with a thin-foil target

Sagisaka, Akito; Pirozhkov, A. S.; Mori, Michiaki; Yogo, Akifumi; Ogura, Koichi; Orimo, Satoshi; Nishiuchi, Mamiko; Ma, J.*; Kiriyama, Hiromitsu; Kanazawa, Shuhei; et al.

NIFS-PROC-85, p.30 - 33, 2011/02

The experiment of proton generation is performed for developing the laser-driven ion source. We observe proton signals in the laser-plasma interaction by using a thin-foil target. To get higher energy protons the size of the preformed plasma is reduced by changing the laser contrast level. In the high-contrast laser pulse case the maximum energy of the protons generated at rear side of the target increases.

Journal Articles

Proton generation and terahertz radiation from a thin-foil target with a high-intensity laser

Sagisaka, Akito; Pirozhkov, A. S.; Mori, Michiaki; Yogo, Akifumi; Ogura, Koichi; Orimo, Satoshi; Nishiuchi, Mamiko; Ma, J.*; Kiriyama, Hiromitsu; Kanazawa, Shuhei; et al.

Reza Kenkyu, 38(9), p.702 - 705, 2010/09

High-intensity laser and thin-foil interactions produce high-energy particles, hard X-ray, high-order harmonics, and terahertz (THz) radiation. A proton beam driven by a high-intensity laser has received attention as a compact ion source for medical applications. In this study we have tested simultaneous generation of protons and THz radiation from a thin-foil target. We use a Ti:sapphire laser system (J-KAREN) at JAEA. A laser beam is focused by an off-axis parabolic mirror at the thin-foil target. We observed the high-energy proton in the rear side of the target and THz radiation in the reflected direction. Next, high energy protons are observed by reducing the size of preformed plasma.

JAEA Reports

Theoretical study of rock for estimating long-term behavior (Contract research)

Ichikawa, Yasuaki*; Choi, J. H.*; Hirano, Toru; Matsui, Hiroya

JAEA-Research 2009-027, 48 Pages, 2009/10

JAEA-Research-2009-027.pdf:3.75MB

On the radioactive waste disposal, the long-term mechanical stability of tunnel was required. Therefore, we have been developing the method evaluating the stability. This report describes the works in the FY2008. Chapter 1 is the overview. In Chapter 2 we performed pressure dissolution experiments using specimens of single crystal quartz, since the dissolution reaction is engaged with a deformation and failure process of polycrystalline rock. After applying stress the surface of contacted area of quartz was observed by microscope and found traces of dissolution and reprecipitation. We managed two types of experiment; a closed solution experiment and a flow-through experiment. We discussed the Si dissolution rate based on the experimental results measured by ICP-AES. Fundamental mechanism of time-dependent creep and stress relaxation for crystalline rocks was discussed in Chapter 3 based on a concept of mechano-chemical coupling phenomena (as treated in Chapter 2) at micro-crack tips.

Journal Articles

International and regional control of nuclear fuel cycle

Choi, J.-S.*; Kuno, Yusuke

Genshiryoku eye, 55(5), p.59 - 63, 2009/05

The paper provides a historical account of some of the most relevant proposals, concepts, and studies of international control over technologies and materials in the proliferation sensitive parts of the nuclear fuel cycle. It also focuses on recent proposals which aim to reduce or eliminate the incentive of countries developing sensitive fuel cycle technologies, namely, enrichment and reprocessing. Many of these proposals include the reliable fuel supply and perhaps, spent fuel take-back. The objectives of the cooperative framework are to facilitate member parties to form partnerships for providing nuclear fuel-cycle service needs; to coordinate international safeguards and inspection of fuel-cycle facilities; to assure that member parties would receive the reliable and economically-competitive fuel-cycle services; and to enhance the profile of peaceful use of nuclear power in Asia Pacific.

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