Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Domal, S. J.*; Correa-Alfonso, C. M.*; Paulbeck, C. J.*; Griffin, K. T.*; Sato, Tatsuhiko; Funamoto, Sachiyo*; Cullings, H. M.*; Egbert, S. D.*; Endo, Akira; Hertel, N. E.*; et al.
Health Physics, 125(4), p.245 - 259, 2023/10
Times Cited Count：0 Percentile：0.01(Environmental Sciences)The RERF Working Group on Organ Dose (WGOD) has established the J45 (Japan 1945) series of high-resolution voxel phantoms, which were derived from the UF/NCI series of hybrid phantoms and scaled to match mid-1940s Japanese body morphometries. In this present study, we present the J45 pregnant female phantoms in both a kneeling and lying posture, and assess the dosimetric impact of these more anatomically realistic survivor models in comparisons to current organ doses given by the DS02 system. For the kneeling phantoms facing the bomb hypocenter, organ doses from bomb source photon spectra were shown to be overestimated by the DS02 system by up to a factor of 1.45 for certain fetal organs and up to a factor of 1.17 for maternal organs. For lying phantoms with their feet in the direction of the hypocenter, fetal organ doses from bomb source photon spectra were underestimated by the DS02 system by factors as low as 0.77 while maternal organ doses were overestimated by up to a factor of 1.38. Results from this study highlight the degree to which the existing DS02 system can differ from organ dosimetry based upon 3D radiation transport simulations using more anatomically realistic models of those survivors exposed during pregnancy while in a kneeling or lying position.
Paulbeck, C. J.*; Sato, Tatsuhiko; Funamoto, Sachiyo*; Lee, C.*; Griffin, K. T.*; Cullings, H. M.*; Egbert, S. D.*; Endo, Akira; Hertel, N. E.*; Bolch, W. E.*
Radiation and Environmental Biophysics, 62(3), p.317 - 329, 2023/08
Times Cited Count：0 Percentile：0.01(Biology)In our prior study [Radiat Res 192, 538-561 (2019)], we presented a new J45 (Japanese 1945) series of high-resolution phantoms of the adult pregnant female at 8-week, 15-week, 25-week, and 38-week post-conception. In this present study, we extend this work using realistic angular fluences from the DS02 system for up to nine different radiation categories and five shielding conditions. General findings are that the current DS02 fetal dose surrogate overestimates values of fetal organ dose seen in the J45 phantoms towards the cranial end of the fetus, especially in the later stages of pregnancy. This work supports our previous findings that the J45 pregnant female phantom series offers significate opportunities for gestational age-dependent assessment of fetal organ dose without the need to invoke the uterine wall as a fetal organ surrogate.
Taira, Yoshitaka*; Endo, Shunsuke; Kawamura, Shiori*; Nambu, Taro*; Okuizumi, Mao*; Shizuma, Toshiyuki*; Omer, M.; Zen, H.*; Okano, Yasuaki*; Kitaguchi, Masaaki*
Physical Review A, 107(6), p.063503_1 - 063503_10, 2023/06
Times Cited Count：0 Percentile：0.01(Optics)no abstracts in English
Katano, Ryota; Oizumi, Akito; Fukushima, Masahiro; Pyeon, C. H.*; Yamamoto, Akio*; Endo, Tomohiro*
Nuclear Science and Engineering, 20 Pages, 2023/00
Times Cited Count：0 Percentile：0.01(Nuclear Science & Technology)In this study, we have demonstrated that data assimilation using lead and bismuth sample reactivities measured in the Kyoto University Critical Assembly A-core can successfully reduce the uncertainty of the coolant void reactivity in accelerator-driven systems derived from inelastic-scattering cross-sections of lead and bismuth. We re-evaluated and highlighted the experimental uncertainties and correlations of the sample reactivities for the data assimilation formula. We used the MCNP6.2 code to evaluate the sample reactivities and their uncertainties, and performed data assimilation using the reactor analysis code system MARBLE. The high-sensitivity coefficients of the sample reactivities to lead and bismuth allowed us to reduce the cross-section-induced uncertainty of the void reactivity of the accelerator-driven system from 6.3% to 4.8%, achieving a provisional target accuracy of 5% in this study. Furthermore, we demonstrated that the uncertainties arising from other dominant factors, such as minor actinides and steel, can be effectively reduced by using integral experimental data sets for the unified cross-section dataset ADJ2017.
PbShizuma, Toshiyuki*; Endo, Shunsuke; Kimura, Atsushi; Massarczyk, R.*; Schwengner, R.*; Beyer, R.*; Hensel, T.*; Hoffmann, H.*; Junghans, A.*; R
mer, K.*; et al.
Physical Review C, 106(4), p.044326_1 - 044326_11, 2022/10
Times Cited Count：1 Percentile：0.02(Physics, Nuclear)no abstracts in English
Endo, Shunsuke; Shizuma, Toshiyuki*; Zen, H.*; Taira, Yoshitaka*; Omer, M.; Kawamura, Shiori*; Abe, Ryota*; Okudaira, Takuya*; Kitaguchi, Masaaki*; Shimizu, Hirohiko*
UVSOR-49, P. 38, 2022/08
Griffin, K. T.*; Sato, Tatsuhiko; Funamoto, Sachiyo*; Chizhov, K.*; Domal, S.*; Paulbeck, C.*; Bolch, W.*; Cullings, H. M.*; Egbert, S. D.*; Endo, Akira; et al.
Radiation and Environmental Biophysics, 61(1), p.73 - 86, 2022/03
Times Cited Count：5 Percentile：53.7(Biology)To evaluate the potential dosimetry improvements that would arise from their use in a Dosimetry System (DS) at RERF, we have evaluated organ doses in the J45 series using the environmental fluence data for twenty generalized survivor scenarios pulled directly from the current DS. The energy- and angle-dependent gamma and neutron fluences were converted to a phase space source term for use in MCNP6, a modern radiation transport code. Overall, the updated phantom series would be expected to provide dose improvements to several important organs, including the active marrow, colon, and stomach wall (up to 20%, 20%, and 15% impact on total dose, respectively). The impacts on dosimetry were especially significant for neutron dose estimates (up to a two-fold difference) and within organs which were unavailable in the previous phantom series, such as the skin, esophagus, and prostate.
Petoussi-Henss, N.*; Satoh, Daiki; Endo, Akira; Eckerman, K. F.*; Bolch, W. E.*; Hunt, J.*; Jansen, J. T. M.*; Kim, C. H.*; Lee, C.*; Saito, Kimiaki; et al.
Annals of the ICRP, 49(2), p.11 - 145, 2020/10
The age-dependent dose coefficients of organ equivalent doses and effective doses for the member of the public are required to estimate the external dose of the public exposed to radiations from radionuclides in the environment. For this purpose, a computational method to simulate the radiation fields of environmental photon and electron sources in the air, soil, and water has been developed using a particle transport code PHITS in the JAEA, and the organ equivalent doses have been calculated using the human models of newborns, 1-year-old, 5-years-old, 10-years-old, and 15-years-old children, and adults male and female provided by the ICRP. In addition, the nuclide-specific effective dose coefficients have been derived using the skin-dose data and nuclide-decay data provided by the Hanyang University and ICRP, respectively. The data of the dose coefficients are available for dose estimations of not only the Fukushima Daiichi nuclear accident but radiological emergencies which radionuclides are released to the environment.
Sato, Tatsuhiko; Funamoto, Sachiyo*; Paulbeck, C.*; Griffin, K.*; Lee, C.*; Cullings, H.*; Egbert, S. D.*; Endo, Akira; Hertel, N.*; Bolch, W. E.*
Radiation Research, 194(4), p.390 - 402, 2020/10
Times Cited Count：6 Percentile：45.74(Biology)Owing to recent advances in computational dosimetry tools, it is desirable to update the dosimetry system for the atomic-bomb survivors as it was established by DS02. In the current study, we have investigated the possible impact of introducing not only the J45 phantom series but also various methodological upgrades to the DS02 dosimetry system. It was found that the anatomical improvement in the J45 phantom series is the most important factor leading to potential changes in survivor organ doses. In addition, this study established a series of response functions which allows for the rapid conversion of the unidirectional quasi-monoenergetic photon and neutron fluences to organ doses within the J45 adult phantoms. This system of response functions can be implemented within a revision to the DS02 dosimetry system and used for future updates to organ doses within the Life Span Study of the atomic-bomb survivors.
Np and 
Am by accelerator-driven system at Kyoto University Critical AssemblyPyeon, C. H.*; Yamanaka, Masao*; Oizumi, Akito; Fukushima, Masahiro; Chiba, Go*; Watanabe, Kenichi*; Endo, Tomohiro*; Van Rooijen, W. G.*; Hashimoto, Kengo*; Sakon, Atsushi*; et al.
Journal of Nuclear Science and Technology, 56(8), p.684 - 689, 2019/08
Times Cited Count：12 Percentile：79.53(Nuclear Science & Technology)This study demonstrates, for the first time, the principle of nuclear transmutation of minor actinide (MA) by the accelerator-driven system (ADS) through the injection of high-energy neutrons into the subcritical core at the Kyoto University Critical Assembly. The main objective of the experiments is to confirm fission reactions of neptunium-237 (Np) and americium-241 (Am), and capture reactions of Np. Subcritical irradiation of Np and Am foils is conducted in a hard spectrum core with the use of the back-to-back fission chamber that obtains simultaneously two signals from specially installed test (Np or Am) and reference (uranium-235) foils. The first nuclear transmutation of Np and Am by ADS soundly implemented by combining the subcritical core and the 100 MeV proton accelerator, and the use of a lead-bismuth target, is conclusively demonstrated through the experimental results of fission and capture reaction events.
Paulbeck, C.*; Griffin, K.*; Lee, C.*; Cullings, H.*; Egbert, S. D.*; Funamoto, Sachiyo*; Sato, Tatsuhiko; Endo, Akira; Hertel, N.*; Bolch, W. E.*
Radiation Research, 192(5), p.538 - 561, 2019/08
Times Cited Count：13 Percentile：64.47(Biology)An important cohort of the atomic bomb survivors are pregnant females exposed to the photon and neutrons fields at both Hiroshima and Nagasaki, as well as their children who were exposed 
. In the present study, we present a new J45 (Japanese 1945) series of high-resolution phantoms of the adult pregnant female at 8-week, 15-week, 25-week, and 38-week post-conception. As for the maternal organ doses, the use of organ doses in a non-pregnant female were shown, in general, to overestimate the corresponding organ doses in the pregnant female, with greater deviations seen at later stages of pregnancy. These results demonstrate that the J45 pregnant female phantom series offers the opportunity for significant improvements in both fetal and maternal organ dose assessment within this unique cohort of the atomic bomb survivors.
Griffin, K.*; Paulbeck, C.*; Bolch, W.*; Cullings, H.*; Egbert, S. D.*; Funamoto, Sachiyo*; Sato, Tatsuhiko; Endo, Akira; Hertel, N.*; Lee, C.*
Radiation Research, 191(4), p.369 - 379, 2019/04
Times Cited Count：17 Percentile：73.42(Biology)Due to computing limitations of the time, only three stylized phantoms were used in DS86 and DS02 to represent the entire Japanese population: an infant, child, and adult. Our study aimed to evaluate the dosimetric impact that should be expected from using an updated and age-expanded RERF phantom series with the survivor cohort. To this end, we developed a new series of hybrid phantoms, based on the Japanese population of 1945, which has greater anatomical realism and improved age resolution than those previously used by RERF. From the photon portion of the spectra, dose differences of up to nearly 25% are expected between the old and new series, while differences of up to nearly 70% are expected from the neutron portion. Overall, our new series of phantoms has shown to provide significant improvements to survivor organ dosimetry, especially to those survivors who were previously misrepresented in body size by their stylized phantom and to those who experienced a highly-directional irradiation field.
Endo, Akira; Petoussi-Henss, N.*; Zankl, M.*; Bolch, W. E.*; Eckerman, K. F.*; Hertel, N. E.*; Hunt, J. G.*; Pelliccioni, M.*; Schlattl, H.*; Menzel, H.-G.*
Radiation Protection Dosimetry, 161(1-4), p.11 - 16, 2014/10
Times Cited Count：3 Percentile：16.35(Environmental Sciences)In 2007, the International Commission on Radiological Protection (ICRP) revised its fundamental recommendations on radiation protection in ICRP Publication 103 (ICRP103). The recommendations updated the radiation and tissue weighting factors in the radiological protection quantities, equivalent and effective doses, and adopted reference computational phantoms for the calculation of organ doses. These revisions required calculations of conversion coefficients for the protection quantities. The sets of conversion coefficients for external exposures were compiled by the Task Group DOCAL of ICRP, and published in ICRP116. The presentation reviews the conversion coefficients for external radiations calculated using the reference computational phantoms. The conversion coefficients are compared with the existing values given in ICRP74. Contributing factors for any differences between these sets of conversion coefficients as well as the impact for radiation monitoring practice are discussed.
Petoussi-Henss, N.*; Bolch, W. E.*; Eckerman, K. F.*; Endo, Akira; Hertel, N.*; Hunt, J.*; Menzel, H. G.*; Pelliccioni, M.*; Schlattl, H.*; Zankl, M.*
Physics in Medicine & Biology, 59(18), p.5209 - 5224, 2014/09
Times Cited Count：13 Percentile：47.84(Engineering, Biomedical)ICRP Publication 116 (ICRP116) on "Conversion Coefficients for Radiological Protection Quantities for External Radiation Exposures", provides fluence-to-dose conversion coefficients for organ absorbed doses and effective dose for external exposures. ICRP116 supersedes the ICRP74, expanding also the particle types and energy ranges considered. The coefficients were calculated using the ICRP/ICRU computational phantoms representing the Reference Adult Male and Reference Adult Female, together with Monte Carlo codes simulating the radiation transport in the body. Idealised whole-body irradiation from unidirectional and rotational parallel beams as well as isotropic irradiation was considered. Comparison of the effective doses with operational quantities revealed that the latter quantities continue to provide a good approximation of effective dose for photons, neutrons and electrons for the conventional energy ranges considered previously, but not at the higher energies of ICRP116.
R
hm, W.*; Mares, V.*; Pioch, C.*; Agosteo, S.*; Endo, Akira; Ferrarini, M.*; Rakhno, I.*; Rollet, S.*; Satoh, Daiki; Vincke, H.*
Radiation Measurements, 67, p.24 - 34, 2014/08
Times Cited Count：18 Percentile：79.96(Nuclear Science & Technology)In order to investigate the impact of the difference of the transport code on the response calculation of Bonner Sphere, EURADOS (European Radiation Dosimetry Group) initiated an exercise where six groups having experience in neutron transport calculations with the MC codes (MCNP, MCNPX, FLUKA, PHITS, MARS, or GEANT4) calculated the responses of a bare 
He proportional counter, a He proportional counter embedded in the middle of a 9 inch polyethylene sphere, and a He proportional counter centred in a 9 inch polyethylene sphere containing a lead shell, at neutron energies of 1, 10, 100, and 1,000 MeV.
Yamasaki, Chisato*; Murakami, Katsuhiko*; Fujii, Yasuyuki*; Sato, Yoshiharu*; Harada, Erimi*; Takeda, Junichi*; Taniya, Takayuki*; Sakate, Ryuichi*; Kikugawa, Shingo*; Shimada, Makoto*; et al.
Nucleic Acids Research, 36(Database), p.D793 - D799, 2008/01
Times Cited Count：52 Percentile：71.15(Biochemistry & Molecular Biology)Here we report the new features and improvements in our latest release of the H-Invitational Database, a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of fulllength cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 protein-coding and 642 non-protein-coding loci; 858 transcribed loci overlapped with predicted pseudogenes.
Tran, V. H.; Satoh, Daiki; Takahashi, Fumiaki; Tsuda, Shuichi; Endo, Akira; Saito, Kimiaki; Yamaguchi, Yasuhiro
JAERI-Tech 2004-079, 37 Pages, 2005/02
JAERI-Tech-2004-079.pdf:5.02MB
no abstracts in English
Endo, Akira; Kim, E.; Yamaguchi, Yasuhiro; Sato, Tatsuhiko; Yoshizawa, Michio; Tanaka, Susumu; Nakamura, Takashi; Rasolonjatovo, A. H. D.*
Journal of Nuclear Science and Technology, 41(Suppl.4), p.510 - 513, 2004/03
no abstracts in English
Takeda, Masayasu; Endo, Yasuo*; Kamijo, Atsushi*; Langridge, S.*; Dalgliesh, R.*; Her, J. H.*; Lee, K. B.*
Transactions of the Materials Research Society of Japan, 28, p.23 - 26, 2003/11
no abstracts in English
Matsumura, Akira*; Yamamoto, Tetsuya*; Shibata, Yasushi*; Nakai, Kei*; Zhang, T.*; Matsushita, Akira*; Takano, Shingo*; Endo, Kiyoshi*; Akutsu, Hiroyoshi*; Yamamoto, Kazuyoshi; et al.
Research and Development in Neutron Capture Therapy, p.1073 - 1078, 2002/09
Since 1998 to 2002, a new clinical trial of an intraoperative boron neutron capture therapy (IOBNCT) at JRR-4 of Japan Atomic Energy Institute (JAERI) using BSH with mixed thermal/epithermal neutron beam has been accomplished. There have been 9 patients included in this study. The median survival time (MST) in GBM was 19.8 months and 16.8 months in AA. IOBNCT with mixed thermal/epithermal neutron beam provide better primary radiation effect than conventional therapy in selected cases. Our phase I/II clinical trial was effective in local tumor control. Further clinical trial with new design should be performed to prove the efficacy of IOBNCT.
