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-induced total reaction cross sections based on the intranuclear cascade modelNakano, Masahiro*; Yamaguchi, Yuji; Furuta, Toshimasa*; Uozumi, Yusuke*
Physical Review C, 110(6), p.064620_1 - 064620_5, 2024/12
Times Cited Count：0 Percentile：0.00(Physics, Nuclear)Alpha-induced total reaction cross sections in the low-energy region below 400 MeV are investigated using an intranuclear cascade model based on the extended framework for nucleon- and deuteron-induced reactions. Experimental data for 
C, 
Si, 
Ca, and 
Pb targets are reproduced well by calculations performed with reasonable parameters close to those determined in other studies. It is shown that two effects, namely, discrete level constraint (DLC) and the Coulomb effect, provide important contributions that depend on the incident- energy and target. The DLC effect is limited to a narrow region of low-energy and is very important in light targets. The Coulomb effect is decisive on cross sections in Pb, while the DLC contribution for the heavy target is small. It is concluded that this trend in the contribution of both effects is consistent with proton- and deuteron-induced total reaction cross sections.
Ogawa, Tatsuhiko; Hirata, Yuho; Matsuya, Yusuke; Kai, Takeshi; Sato, Tatsuhiko; Iwamoto, Yosuke; Hashimoto, Shintaro; Furuta, Takuya; Abe, Shinichiro; Matsuda, Norihiro; et al.
EPJ Nuclear Sciences & Technologies (Internet), 10, p.13_1 - 13_8, 2024/11
The latest updates on PHITS, a versatile radiation transport code, focusing specifically on track-structure models are presented. Track structure calculations are methods used to simulate the movement of charged particles while explicitly considering each atomic reaction. Initially developed for radiation biology, these calculation methods aimed to analyze the radiation-induced damage to DNA and chromosomes. Several track-structure calculation models, including PHITS-ETS, PHITS-ETS for Si, PHITS-KURBUC, ETSART, and ITSART, have been developed and implemented to PHITS. These models allow users to study the behavior of various particles at the nano-scale across a wide range of materials. Furthermore, potential applications of track-structure calculations have also been proposed so far. This collection of track-structure calculation models, which encompasses diverse conditions, opens up new avenues for research in the field of radiation effects.
and 
study of biological effects on cancer cells in the presence of metallic materials during radiotherapyNagano, Takuya*; Matsuya, Yusuke; Kaida, Atsushi*; Nojima, Hitomi*; Furuta, Takuya; Sato, Kaoru; Yoshimura, Ryoichi*; Miura, Masahiko*
Journal of Radiation Research (Internet), 65(5), p.628 - 639, 2024/09
Times Cited Count：0 Percentile：0.00(Biology)In X-ray therapy, radiation regimen is planned to eliminate tumors while minimizing side effects on normal tissue. When irradiating the oral cavity, which includes dental metallic crowns, intense mucositis can occasionally be induced. However, the mechanism underlying the radiosensitization remains unclear. In this study, we investigated the radiosensitization mechanism using cell experiments and computational simulations. As a result, the enhancement ratio observed in the cell experiments was 1.2-1.4, which was found to be predominately attributed to local dose increase near metal. On the other hand, as a result of dose evaluation based on CT images as a preclinical test, it was found that the dose increase was underestimated due to the complex anatomical structure of the human body, and microscopic dose evaluation was necessary. This outcome contributes to the precise understanding of side effects on normal cells around metals.
Ishikawa, Akihisa; Koba, Yusuke*; Furuta, Takuya; Chang, W.*; Yonai, Shunsuke*; Matsumoto, Shinnosuke*; Hashimoto, Shintaro; Hirai, Yuta*; Sato, Tatsuhiko
Radiological Physics and Technology, 17(2), p.553 - 560, 2024/06
particle impinging on Al at 230 MeV/uFuruta, Toshimasa*; Uozumi, Yusuke*; Yamaguchi, Yuji; Iwamoto, Yosuke; Koba, Yusuke*; Velicheva, E.*; Kalinnikov, V.*; Tsamalaidze, Z.*; Evtoukhovitch, P.*
Journal of Nuclear Science and Technology, 61(2), p.230 - 236, 2024/02
Times Cited Count：0 Percentile：0.00(Nuclear Science & Technology)Charged particle production from particle fragmentation reactions was investigated experimentally by measurement of 230-MeV/u particles bombarding an aluminum target. Double differential cross sections were measured for each ejectile of p, d, t, 
He, and 
He at laboratory angles between 15 and 60 deg. The results of analyzed data found the following common characteristics: (1) spectra of proton- and neutron-emission are similar in high energy region at forward angle, (2) triton-to-He ratio of -breakup yield is 1:2, which is similar to lower incident energy experiment, and (3) the shape of broad peak formed by He and particles could be explained by the process with collision between induced particle and target nucleus.
Sato, Tatsuhiko; Iwamoto, Yosuke; Hashimoto, Shintaro; Ogawa, Tatsuhiko; Furuta, Takuya; Abe, Shinichiro; Kai, Takeshi; Matsuya, Yusuke; Matsuda, Norihiro; Hirata, Yuho; et al.
Journal of Nuclear Science and Technology, 61(1), p.127 - 135, 2024/01
Times Cited Count：144 Percentile：99.97(Nuclear Science & Technology)The Particle and Heavy Ion Transport code System (PHITS) is a general-purpose Monte Carlo radiation transport code that can simulate the behavior of most particle species with energies up to 1 TeV (per nucleon for ions). Its new version, PHITS3.31, was recently developed and released to the public. In the new version, the compatibility with high-energy nuclear data libraries and the algorithm of the track-structure modes have been improved. In this paper, we summarize the upgraded features of PHITS3.31 with respect to the physics models, utility functions, and application software introduced since the release of PHITS3.02 in 2017.
Furuta, Takuya; Koba, Yusuke*; Hashimoto, Shintaro; Chang, W.*; Yonai, Shunsuke*; Matsumoto, Shinnosuke*; Ishikawa, Akihisa*; Sato, Tatsuhiko
Physics in Medicine & Biology, 67(14), p.145002_1 - 145002_15, 2022/07
Times Cited Count：8 Percentile：68.93(Engineering, Biomedical)Carbon ion radiotherapy has an advantage over conventional radiotherapy such that its superior dose concentration on the tumor helps to reduce unwanted dose to surrounding normal tissues. Nevertheless, a little dose to normal tissues, which is a potential risk of secondary cancer, is still unavoidable. The Monte Carlo simulation is a good candidate for the tool to assess secondary cancer risk, including the contributions of secondary particles produced by nuclear reactions. We therefore developed a new dose reconstruction system implementing PHITS as the engine. In this system, the PHITS input is automatically created from the DICOM data sets recorded in the treatment planning. The developed system was validated by comparing to experimental dose distribution in water and treatment plan on an anthropomorphic phantom. This system will be used for retrospective studies using the patient data in National Institute for Quantum and Science and Technology.
Chang, W.*; Koba, Yusuke*; Furuta, Takuya; Yonai, Shunsuke*; Hashimoto, Shintaro; Matsumoto, Shinnosuke*; Sato, Tatsuhiko
Journal of Radiation Research (Internet), 62(5), p.846 - 855, 2021/09
Times Cited Count：4 Percentile：32.45(Biology)With the aim of developing a revaluation tool of treatment plan in carbon-ion radiotherapy using Monte Carlo (MC) simulation, we propose two methods; one is dedicated to identify realistic-tissue materials from a CT image with satisfying the well-calibrated relationship between CT numbers and stopping power ratio (SPR) provided by TPS, and the other is to estimate dose to water considering the particle- and energy-dependent SPR between realistic tissue materials and water. We validated these proposed methods by computing depth dose distribution in homogeneous and heterogeneous phantoms composed of human tissue materials and water irradiated by a 400 MeV/u carbon beam with 8 cm SOBP using a MC simulation code PHITS and comparing with results of conventional treatment planning system (TPS). Our result suggested that use of water as a surrogate of real tissue materials, which is adopted in conventional TPS, is inadequate for dose estimation from secondary particles because their production rates cannot be scaled by SPR of the primary particle in water. We therefore concluded that the proposed methods can play important roles in the reevaluation of the treatment plans in carbon-ion radiotherapy.
Shiine, Yasuharu*; Nishikawa, Hiroyuki*; Furuta, Yusuke*; Kanamitsu, Kaoru*; Sato, Takahiro; Ishii, Yasuyuki; Kamiya, Tomihiro; Nakao, Ryota*; Uchida, Satoshi*
Microelectronic Engineering, 87(5-8), p.835 - 838, 2010/05
Times Cited Count：7 Percentile：41.62(Engineering, Electrical & Electronic)Kamiya, Tomihiro; Takano, Katsuyoshi; Ishii, Yasuyuki; Sato, Takahiro; Oikawa, Masakazu*; Okubo, Takeru; Haga, Junji*; Nishikawa, Hiroyuki*; Furuta, Yusuke*; Uchiya, Naoyuki*; et al.
Nuclear Instruments and Methods in Physics Research B, 267(12-13), p.2317 - 2320, 2009/06
Times Cited Count：7 Percentile：46.18(Instruments & Instrumentation)Kamiya, Tomihiro; Nishikawa, Hiroyuki*; Sato, Takahiro; Haga, Junji; Oikawa, Masakazu*; Ishii, Yasuyuki; Okubo, Takeru; Uchiya, Naoyuki; Furuta, Yusuke*
Applied Radiation and Isotopes, 67(3), p.488 - 491, 2009/03
Times Cited Count：5 Percentile：34.78(Chemistry, Inorganic & Nuclear)Development of a mask-less ion beam lithography technique for fabricating micro- or nano-meter sized structures has been started at the microbeam systems in the ion accelerator facility of JAEA Takasaki (TIARA) in collaboration with Shibaura Institute of Technology. In order to obtain a high precision measure for microbeam size estimation and lens system optimization, or for improvement of spatial resolution down to 100 nm level, we applied this lithography technique itself combined with the electroplating process to make a Ni relief pattern as an optimum resolution standard to be used in secondary electron imaging. In this work, using this standard, the smallest beam size could be obtained. This paper also discuses on the scattering of ions in the materials influenced to the resolution using a Monte Carlo simulation code.
Uchiya, Naoyuki*; Furuta, Yusuke*; Nishikawa, Hiroyuki*; Watanabe, Toru*; Haga, Junji; Sato, Takahiro; Oikawa, Masakazu; Ishii, Yasuyuki; Kamiya, Tomihiro
Microsystem Technologies, 14(9-11), p.1537 - 1540, 2008/10
Times Cited Count：17 Percentile：63.40(Engineering, Electrical & Electronic)Hashimoto, Shintaro; Sato, Tatsuhiko; Iwamoto, Yosuke; Ogawa, Tatsuhiko; Furuta, Takuya; Abe, Shinichiro; Kai, Takeshi; Matsuya, Yusuke; Matsuda, Norihiro; Hirata, Yuho; et al.
no journal, ,
PHITS is a general-purpose radiation transport simulation code that has been developed mainly by JAEA in cooperation with domestic and foreign research institutes. PHITS can simulate various radiation behaviors in all kinds of materials, and has been used by more than 7,000 researchers and engineers in a wide range of fields, including science, engineering, and medicine. We released the latest version, PHITS 3.27, in March 2022. This version includes several valuable improvements such as ITSART, a track-structure mode for arbitrary materials, and availability of nuclear data libraries for deuterons, alpha particles, and photons. In this presentation, we will introduce the new improvements and their features.
-ray directional radiation dose detector with good efficiency for field surveyYamamori, Ryo*; Kobayashi, Hikaru*; Honta, Shohei*; Yoshino, Hiroshi*; Nozaki, Atsuo*; Ichijo, Yusuke*; Hijikata, Yoshio*; Yoshida, Hiroko*; Furuta, Takuya
no journal, ,
Understanding radiation field is important to predict radiation dose rate in newly constructing buildings in an area widely contaminated by radioactive nuclei. Directional spectra of the radiations are important to consider the shielding effect of the building. We adopts a method to measure the directional spectra by adopting a plate of lead collimator in front of the scintillator and subtract the values from the spectra measured without lead collimator. We investigated a possible weight saving detection system having sufficient detection efficiency. The investigation was carried out for the condition of the collimator radius (
= 10, 15, 20 cm) and the distance between collimator and detector (
= 1, 3, 5 cm). We found that three combinations satisfied the 90
field view and the detection efficiency became better with larger collimator radius. On the other hand, larger collimator radius indicate heavier detection system. Therefore, we developed an optimum detection system for field survey with the 15 cm diameter plate (10kg), the scintillator (3.4kg), and the folder (1.0kg).
Shiine, Yasuharu*; Nishikawa, Hiroyuki*; Furuta, Yusuke*; Sato, Takahiro; Ishii, Yasuyuki; Kamiya, Tomihiro; Nakao, Ryota*; Uchida, Satoshi*
no journal, ,
Chang, W.*; Koba, Yusuke*; Furuta, Takuya; Yonai, Shunsuke*; Hashimoto, Shintaro; Matsumoto, Shinnosuke*; Sato, Tatsuhiko
no journal, ,
In the treatment planning system (TPS) for radiotherapy, approximate calculation by replacing all materials with water and accounting only the density variation is adopted to reduce the computational cost. On the other hand, conversion from patient CT data to elemental compositions and densities is required to conduct Monte Carlo simulation. Especially for the assessment of secondary cancer risk in carbon therapy, secondary particles produced in the nuclear reaction between incident carbons and human tissues are important so that the difference of the elemental compositions is essential. We have therefore developed a method to convert CT number to human tissues keeping the consistency with the water stopping power table embedded in TPS. We applied this conversion method to 9 different human tissues and confirmed the range of carbon beams are reproduced within 1 mm precision for all the materials.
Furuta, Yusuke*; Uchiya, Naoyuki*; Nishikawa, Hiroyuki*; Haga, Junji; Oikawa, Masakazu*; Sato, Takahiro; Ishii, Yasuyuki; Kamiya, Tomihiro
no journal, ,
no abstracts in English
Ogawa, Tatsuhiko; Iwamoto, Yosuke; Hashimoto, Shintaro; Sato, Tatsuhiko; Matsuda, Norihiro; Kunieda, Satoshi; 
elik, Y.*; Furutachi, Naoya*; Niita, Koji*; Furuta, Takuya; et al.
no journal, ,
PHITS is a general-purpose radiation transport simulation code that has been developed mainly by JAEA in cooperation with domestic and foreign research institutes. We released the latest version, PHITS 3.27, in March 2022. Since SATIF-14 held in 3 years ago, following updates were implemented (1)Extension of the cross section data reading module, (2)Modernization of burn-up calculation code DCHAIN, (3)Functionality to calculate the dependence of the result on the input parameters, (4)Interactive 3D geometry viewer,PHIG-3D, (5)Cosmic ray source function, (6)Track-structure calculation models, which calculate the atomic-scale reactions of charged particles on event-by-event basis, for electrons, positions, and heavy ions, (7)GUI-version RT-PHITS development, (8)random number generation by Xor-shift64 algorithm, (9)User-defined stopping power reading module, (10)EXFOR data reading module, (11)Photon-induced mu-mu pair production model. In addition, a bench, ark study conducted by Iwamoto et al, is also presented to explain the importance of the new cross section reading module.
Nagano, Takuya*; Matsuya, Yusuke; Kaida, Atsushi*; Nojima, Hitomi*; Furuta, Takuya; Sato, Kaoru; Yoshimura, Ryoichi*; Miura, Masahiko*
no journal, ,
A dental prosthesis such as a metal crown exists in radiation field when performing head and neck cancer radiotherapy. In our previous studies, we have evaluated the sensitizing effect ratio (SER) of the radiobiological effects around metal crowns by in vitro analysis. However, it is uncertain how much SER is actually expected in complex geometry in clinical practice. Here, we simulated the treatment plan using a head phantom with a metal crown, and evaluated the dose distributions around the metal crown in a realistic patient system by simulation. The simulation results using PHITS agree well with the SER values obtained in vitro. It has been known that localized mucositis occurs around metal crowns during radiotherapy, and this outcome is expected to provide a precise understanding of the mechanism on inflammation in tissues around metals.
of 230 MeV/u incident charged particles production double differential cross sectionFuruta, Toshimasa*; Uozumi, Yusuke*; Yamaguchi, Yuji; Iwamoto, Yosuke; Sanami, Toshiya*; Koba, Yusuke*
no journal, ,
no abstracts in English
