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Hirata, Sakiko*; Kusaka, Ryoji; Meiji, Shogo*; Tamekuni, Seita*; Okudera, Kosuke*; Hamada, Shoken*; Sakamoto, Chihiro*; Honda, Takumi*; Matsushita, Kosuke*; Muramatsu, Satoru*; et al.
Inorganic Chemistry, 62(1), p.474 - 486, 2023/01
Times Cited Count：0 Percentile：0.01(Chemistry, Inorganic & Nuclear)Uehara, Akihiro*; Akiyama, Daisuke*; Ikeda, Atsushi; Numako, Chiya*; Terada, Yasuko*; Nitta, Kiyofumi*; Ina, Toshiaki*; Takeda-Homma, Shino*; Kirishima, Akira*; Sato, Nobuaki*
Journal of Nuclear Materials, 559, p.153422_1 - 153422_11, 2022/02
Times Cited Count：2 Percentile：53.91(Materials Science, Multidisciplinary)Teshigawara, Makoto; Ikeda, Yujiro; Oi, Motoki; Harada, Masahide; Takada, Hiroshi; Kakishiro, Masanori*; Noguchi, Gaku*; Shimada, Tsubasa*; Seita, Kyoichi*; Murashima, Daisuke*; et al.
Nuclear Materials and Energy (Internet), 14, p.14 - 21, 2018/01
Times Cited Count：0 Percentile：0.01(Nuclear Science & Technology)We developed an Au-In-Cd (AuIC) decoupler material to reduce induced radioactivity instead of Ag-In-Cd one, which has a cut off energy of 1eV. In order to implement it into an actual moderator-reflector assembly, a number of critical engineering issues need to be resolved with regard to large-sized bonding between AuIC and A5083 alloys by the hot isostatic pressing process. We investigated this process in terms of the surface conditions, sizes, and heat capacities of large AuIC alloys. We also show a successful implementation of an AuIC decoupler into a reflector assembly, resulting in a remarkable reduction of radioactivity by AuIC compared to AIC without sacrificing neutronic performance.
Tamada, Taro; Shinmi, Daisuke*; Ikeda, Masahiro*; Yonezawa, Yasushi*; Kataoka, Shiro*; Kuroki, Ryota; Mori, Eiji*; Motoki, Kazuhiro*
Scientific Reports (Internet), 5, p.17936_1 - 17936_12, 2015/12
Times Cited Count：25 Percentile：63.52(Multidisciplinary Sciences)The fully human monoclonal antibody KMTR2 acts as a strong direct agonist for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor 2 (TRAIL-R2), which is capable of inducing apoptotic cell death without cross-linking. To investigate the mechanism of direct agonistic activity induced by KMTR2, the crystal structure of the extracellular region of TRAIL-R2 and a Fab fragment derived from KMTR2 (KMTR2-Fab) was determined to 2.1 
resolution. Two KMTR2-Fabs assembled with the complementarity-determining region 2 of the light chain via two-fold crystallographic symmetry, suggesting that the KMTR2-Fab assembly tended to enhance TRAIL-R2 oligomerization. A single mutation at Asn53 to Arg located at the two-fold interface in the KMTR2 resulted in a loss of its apoptotic activity, although it retained its antigen-binding activity. These results indicate that the strong agonistic activity, such as apoptotic signaling and tumor regression, induced by KMTR2 is attributed to TRAIL-R2 superoligomerization induced by the interdimerization of KMTR2.
Fe
O
(=Y, Er, Tm, Yb, Lu and In)Yoshii, Kenji; Ikeda, Naoshi*; Nishihata, Yasuo; Maeda, Daisuke*; Fukuyama, Ryota*; Nagata, Tomoko*; Kano, Jun*; Kambe, Takashi*; Horibe, Yoichi*; Mori, Shigeo*
Journal of the Physical Society of Japan, 81(3), p.033704_1 - 033704_4, 2012/03
Times Cited Count：10 Percentile：55.37(Physics, Multidisciplinary)Exchange bias (EB) behavior has been observed for multiferroic FeO (=Y, Er, Tm, Yb, Lu and In). The materials with the small 
ions (=Tm, Yb, Lu and In) exhibit large EB fields (
1 kOe) below 
100-150 K. This property is rooted in a magnetically glassy state, arising from the competition between ferro- and antiferromagnetic domain interactions. In addition, the exchange bias field tends to be more enhanced for smaller ions. Hence, the EB is controlled by the substitution at the -site in this series.
OOishi, Daisuke*; Hayakawa, Hironori*; Akahama, Hiroshi*; Ikeda, Naoshi*; Kambe, Takashi*; Matsuo, Yoji*; Kimizuka, Noboru*; Kano, Jun*; Yoshii, Kenji
Ferroelectrics, 415(1), p.51 - 56, 2011/10
Times Cited Count：5 Percentile：25.35(Materials Science, Multidisciplinary)The variation of AC dielectric constant in the function of the DC magnetic fields was found in low oxygen vacant LuFeO single crystal in which the electric polarization arise from the polar charge ordering. These magneto-electric coupling should be explained by a novel mechanism where the boundary motion of the polar charge ordered domain is affected by the magnetic (spin) domain boundary motion.
and Au+Au collisions at 
= 200 GeVAdare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Yasuyuki*; Al-Bataineh, H.*; Alexander, J.*; Aoki, Kazuya*; Aphecetche, L.*; Aramaki, Y.*; et al.
Physical Review C, 83(4), p.044912_1 - 044912_16, 2011/04
Times Cited Count：8 Percentile：49.7(Physics, Nuclear)Measurements of electrons from the decay of open-heavy-flavor mesons have shown that the yields are suppressed in Au+Au collisions compared to expectations from binary-scaled collisions. Here we extend these studies to two particle correlations where one particle is an electron from the decay of a heavy flavor meson and the other is a charged hadron from either the decay of the heavy meson or from jet fragmentation. These measurements provide more detailed information about the interaction between heavy quarks and the quark-gluon matter. We find the away-side-jet shape and yield to be modified in Au+Au collisions compared to collisions.
Makino, Takahiro; Onoda, Shinobu; Hirao, Toshio; Oshima, Takeshi; Kobayashi, Daisuke*; Ikeda, Hirokazu*; Hirose, Kazuyuki*
Proceedings of 9th International Workshop on Radiation Effects on Semiconductor Devices for Space Applications (RASEDA-9), p.169 - 172, 2010/10
Digital Single Event Transient (DSET) pulse-widths in an inverter cell fabricated with the 0.2 mm FD-SOI process were estimated from high-energy heavy-ion-induced transient current in a single n-type MOSFET fabricated with the 0.2 mm FD-SOI process. We verified that the estimation method is applicable to the DSET pulse-widths estimation in the case of high-energy heavy-ion irradiation.
OKambe, Takashi*; Komatsu, Takuma*; Michiuchi, Takamasa*; Hayakawa, Hiroki*; Oishi, Daisuke*; Hanasaki, Noriaki*; Yoshii, Kenji; Ikeda, Naoshi*
Journal of Physics; Conference Series, 200, p.012077_1 - 012077_4, 2010/02
Times Cited Count：4 Percentile：80.4(Materials Science, Multidisciplinary)A magneto-electric effect (ME) was observed in a charge-ordered ferroelectric LuFeO. The dielectric response in a three-dimensional charge-ordered phase is strongly influenced by magnetic field, especially around the ferri-magnetic ordering temperature. We also show the relation between the oxygen stoichiometry and the ME signal character above the magnetic transition temperature.
Makino, Takahiro*; Kobayashi, Daisuke*; Hirose, Kazuyuki*; Yanagawa, Yoshimitsu*; Saito, Hirobumi*; Ikeda, Hirokazu*; Takahashi, Daisuke*; Ishii, Shigeru*; Kusano, Masaki*; Onoda, Shinobu; et al.
IEEE Transactions on Nuclear Science, 56(1), p.202 - 207, 2009/02
Times Cited Count：36 Percentile：90.64(Engineering, Electrical & Electronic)SET pulse-widths were measured as a function of LET by using pulse capture circuits and were simulated with mixed-mode 3-D device simulations. We found that the carrier recombination process dominates LET dependence of SET pulse-widths.
OMichiuchi, Takamasa*; Yokota, Yusuke*; Komatsu, Takuma*; Hayakawa, Hironori*; Kuroda, Tomoko*; Maeda, Daisuke*; Matsuo, Yoji*; Mori, Shigeo*; Yoshii, Kenji; Hanasaki, Noriaki*; et al.
Ferroelectrics, 378(1), p.175 - 180, 2009/00
Times Cited Count：18 Percentile：59.66(Materials Science, Multidisciplinary)We have synthesized the samples of LuFeO, which shows the ferroelectricity due to charge ordering of Fe ions, under several different reducing conditions using a CO-CO flow. The reducing condition was changed by changing a flow ratio of CO and CO. It was found that the flow ratio of CO/CO of about 5 provided the sample with the highest magnetic transition temperature of 240-250 K. This sample showed the dielectric constant of 10000 at room temperature. The imaginary part of the dielectric response offered the activation energy of 0.4-0.5 eV, which is slightly larger than that reported previously (about 0.3 eV). We will perform further investigation of the physical properties of this sample to clarify full details and their origin of LuFeO.
O and R
R'
FeO (R, R': rare earths)Yoshii, Kenji; Yoneda, Yasuhiro; Maeda, Daisuke*; Yokota, Yusuke*; Michiuchi, Takamasa*; Komatsu, Takuma*; Ikeda, Naoshi*; Matsuo, Yoji*; Mori, Shigeo*
Japanese Journal of Applied Physics, 47(9), p.7599 - 7602, 2008/09
Times Cited Count：8 Percentile：33.28(Physics, Applied)We have investigated the physical properties of HoFeO and RR'FeO (R, R': rare earths). Dielectric measurements showed their dielectric constants of 1000 at around room temperature, which is characteristic of the RFeO series (R: rare earths). However, the magnetic transition temperatures and the coherency in dielectric response were found to be different from those of RFeO reported so far. Interestingly, these materials suggested higher ferroelectric temperatures than those reported so far, suggesting a possibility of application of these materials.
Makino, Takahiro*; Yanagawa, Yoshimitsu*; Kobayashi, Daisuke*; Fukuda, Seisuke*; Hirose, Kazuyuki*; Ikeda, Hirokazu*; Saito, Hirobumi*; Onoda, Shinobu; Hirao, Toshio; Oshima, Takeshi; et al.
Shingaku Giho, 108(100), p.67 - 72, 2008/06
SET pulse-widths were measured as a function of LET by using pulse capture circuits. In addition, a scan flip-flop (FF) is designed to observe both single event transient (SET) and single event upset (SEU) soft errors in logic VLSI system.
following 
-ray irradiationSakashita, Tetsuya; Hamada, Nobuyuki*; Ikeda, Daisuke*; Suzuki, Michiyo; Yanase, Sumino*; Ishii, Naoaki*; Kobayashi, Yasuhiko
Journal of Radiation Research, 49(3), p.285 - 291, 2008/05
Times Cited Count：12 Percentile：39.72(Biology)We investigated the effects of ionizing radiation (IR) exposure on the relationship between locomotion and salt chemotaxis learning behavior of 
. We found that effects of pre-learning irradiation on locomotion were significantly correlated with the salt chemotaxis learning performance, whereas locomotion was not directly related to chemotaxis to NaCl. On the other hand, locomotion was positively correlated with salt chemotaxis of animals which were irradiated during learning, and the correlation disappeared with increasing doses. These results suggest an indirect relationship between locomotion and salt chemotaxis learning in , and that IR inhibits the innate relationship between locomotion and chemotaxis, which is related to salt chemotaxis learning conditioning of .
subunit of G protein in Sakashita, Tetsuya; Hamada, Nobuyuki*; Ikeda, Daisuke*; Yanase, Sumino*; Suzuki, Michiyo; Ishii, Naoaki*; Kobayashi, Yasuhiko
FASEB Journal, 22(3), p.713 - 720, 2008/03
Times Cited Count：11 Percentile：37.49(Biochemistry & Molecular Biology)We analyzed the effects of ionizing radiation (IR) on a food-NaCl associative learning paradigm of adult , and observed that a decrease in chemotaxis toward NaCl occurs only after combined starvation and exposure to NaCl. Exposure to IR induced an additional decrease in chemotaxis immediately after an acute dose in the transition stage of the food-NaCl associative learning. Strikingly, chronic irradiation induced negative chemotaxis in the exposed animals, i.e., the primary avoidance response. IR-induced additional decreases in chemotaxis following acute and chronic irradiations were significantly suppressed in the 
mutant, which was defective in GPC-1. Chemotaxis to cAMP, but not to lysine and benzaldehyde, was influenced by IR during the food-NaCl associative learning. Our novel findings suggest that IR behaves as a modulator in the food-NaCl associative learning via GPC-1 and a specific neuronal network.
-ray irradiation on olfactory adaptation to benzaldehyde in Sakashita, Tetsuya; Hamada, Nobuyuki*; Suzuki, Michiyo; Ikeda, Daisuke*; Yanase, Sumino*; Ishii, Naoaki*; Kobayashi, Yasuhiko
Uchu Seibutsu Kagaku, 21(4), p.117 - 120, 2007/12
Using as a model organism for studying the nervous system, we investigated the effects of -ray irradiation on olfactory adaptation to benzaldehyde, in which animals show a decrease in chemotaxis to benzaldehyde. Irradiation during the conditioning for adaptation to benzaldehyde did not induce an additional decrease in chemotaxis immediately after irradiation. On the other hand, at 1 h after irradiation, the progress of adaptation to benzaldehyde was interrupted by irradiation with the highest dose. These results indicate that impaired olfactory adaptation to benzaldehyde following irradiation is different from salt chemotaxis learning in . Our findings suggest that the profile of radiation-induced response depends on the function of the nervous system in .
and microbeamSakashita, Tetsuya; Wada, Seiichi; Funayama, Tomoo; Kobayashi, Yasuhiko; Ikeda, Daisuke*; Suzuki, Michiyo*; Tsuji, Toshio*
KEK Proceedings 2005-5, p.53 - 56, 2005/10
no abstracts in English
-irradiation on chemo-attraction to NaCl and food-NaCl associative learning of Sakashita, Tetsuya; Ikeda, Daisuke*; Hamada, Nobuyuki; Suzuki, Michiyo*; Tsuji, Toshio*; Wada, Seiichi; Funayama, Tomoo; Kobayashi, Yasuhiko
no journal, ,
no abstracts in English
Sakashita, Tetsuya; Ikeda, Daisuke*; Hamada, Nobuyuki*; Suzuki, Michiyo*; Tsuji, Toshio*; Wada, Seiichi*; Funayama, Tomoo; Kobayashi, Yasuhiko
no journal, ,
Here we report how food-NaCl associative learning is affected by radiation exposure. Wild-type strain was used for all experiments. The animals were irradiated with 0-500 Gy of -rays. Irradiation did not affect chemotaxis toward NaCl, indicating that sensing and signaling in chemo-attraction are maintained in irradiated animals. It has been reported that chemotaxis was decreased by the association of starvation with chemical stimulation of NaCl. Chemotaxis of animals irradiated during the food-starved conditioning with NaCl was decreased than that of non-irradiated control and temporarily stopped. At several hours after irradiation, the decrease of chemotaxis in irradiated animals was observed again. These results suggest that irradiation perturbed and temporarily stopped a part of neuron network related to associative learning, but not that to chemo-attraction to NaCl.
-irradiation on food-NaCl associative learning of Sakashita, Tetsuya; Ikeda, Daisuke*; Hamada, Nobuyuki*; Suzuki, Michiyo; Tsuji, Toshio*; Wada, Seiichi*; Funayama, Tomoo; Kobayashi, Yasuhiko
no journal, ,
no abstracts in English
