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Kitazawa, Takafumi; Ikeda, Yoichi*; Sakakibara, Toshiro*; Matsuo, Akira*; Shimizu, Yusei*; Tokunaga, Yo; Haga, Yoshinori; Kindo, Koichi*; Nambu, Yusuke*; Ikeuchi, Kazuhiko*; et al.
Physical Review B, 108(8), p.085105_1 - 085105_7, 2023/08
Onuki, Yoshichika*; Kakihana, Masashi*; Iha, Wataru*; Nakaima, Kenri*; Aoki, Dai*; Nakamura, Ai*; Honda, Fuminori*; Nakashima, Miho*; Amako, Yasushi*; Gochi, Jun*; et al.
JPS Conference Proceedings (Internet), 29, p.012001_1 - 012001_9, 2020/02
Teshigawara, Makoto; Ikeda, Yujiro; Oi, Motoki; Harada, Masahide; Takada, Hiroshi; Kakishiro, Masanori*; Noguchi, Gaku*; Shimada, Tsubasa*; Seita, Kyoichi*; Murashima, Daisuke*; et al.
Nuclear Materials and Energy (Internet), 14, p.14 - 21, 2018/01
Times Cited Count:0 Percentile:0.01(Nuclear Science & Technology)We developed an Au-In-Cd (AuIC) decoupler material to reduce induced radioactivity instead of Ag-In-Cd one, which has a cut off energy of 1eV. In order to implement it into an actual moderator-reflector assembly, a number of critical engineering issues need to be resolved with regard to large-sized bonding between AuIC and A5083 alloys by the hot isostatic pressing process. We investigated this process in terms of the surface conditions, sizes, and heat capacities of large AuIC alloys. We also show a successful implementation of an AuIC decoupler into a reflector assembly, resulting in a remarkable reduction of radioactivity by AuIC compared to AIC without sacrificing neutronic performance.
Toyokawa, Hidenori*; Saji, Choji*; Kawase, Morihiro*; Wu, S.*; Hurukawa, Yukihito*; Kajiwara, Kentaro*; Sato, Masugu*; Hirono, Toko*; Shiro, Ayumi*; Shobu, Takahisa; et al.
Journal of Instrumentation (Internet), 12(1), p.C01044_1 - C01044_7, 2017/01
Times Cited Count:4 Percentile:22.34(Instruments & Instrumentation)We have been developing CdTe pixel detectors combined with a Schottky diode sensor and photon-counting ASICs. The hybrid pixel detector was designed with a pixel size of 200 micro-meter by 200 micro-meter and an area of 19 mm by 20 mm or 38.2 mm by 40.2 mm. The photon-counting ASIC, SP8-04F10K, has a preamplifier, a shaper, 3-level window-type discriminators and a 24-bits counter in each pixel. The single-chip detector with 100 by 95 pixels successfully operated with a photon-counting mode selecting X-ray energy with the window comparator and stable operation was realized at 20C. We have performed a feasibility study for a white X-ray microbeam experiment. Laue diffraction patterns were measured during the scan of the irradiated position in a silicon steel sample. The grain boundaries were identified by using the differentials between adjacent images at each position.
Kittaka, Shunichiro*; Shimizu, Yusei*; Sakakibara, Toshiro*; Haga, Yoshinori; Yamamoto, Etsuji; Onuki, Yoshichika; Tsutsumi, Yasumasa*; Nomoto, Takuya*; Ikeda, Hiroaki*; Machida, Kazushige*
Journal of the Physical Society of Japan, 85(3), p.033704_1 - 033704_4, 2016/03
Times Cited Count:30 Percentile:83.27(Physics, Multidisciplinary)Tamada, Taro; Shinmi, Daisuke*; Ikeda, Masahiro*; Yonezawa, Yasushi*; Kataoka, Shiro*; Kuroki, Ryota; Mori, Eiji*; Motoki, Kazuhiro*
Scientific Reports (Internet), 5, p.17936_1 - 17936_12, 2015/12
Times Cited Count:22 Percentile:62.07(Multidisciplinary Sciences)The fully human monoclonal antibody KMTR2 acts as a strong direct agonist for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor 2 (TRAIL-R2), which is capable of inducing apoptotic cell death without cross-linking. To investigate the mechanism of direct agonistic activity induced by KMTR2, the crystal structure of the extracellular region of TRAIL-R2 and a Fab fragment derived from KMTR2 (KMTR2-Fab) was determined to 2.1 resolution. Two KMTR2-Fabs assembled with the complementarity-determining region 2 of the light chain via two-fold crystallographic symmetry, suggesting that the KMTR2-Fab assembly tended to enhance TRAIL-R2 oligomerization. A single mutation at Asn53 to Arg located at the two-fold interface in the KMTR2 resulted in a loss of its apoptotic activity, although it retained its antigen-binding activity. These results indicate that the strong agonistic activity, such as apoptotic signaling and tumor regression, induced by KMTR2 is attributed to TRAIL-R2 superoligomerization induced by the interdimerization of KMTR2.
Oguri, Hidetomo; Hasegawa, Kazuo; Ito, Takashi; Chishiro, Etsuji; Hirano, Koichiro; Morishita, Takatoshi; Shinozaki, Shinichi; Ao, Hiroyuki; Okoshi, Kiyonori; Kondo, Yasuhiro; et al.
Proceedings of 11th Annual Meeting of Particle Accelerator Society of Japan (Internet), p.389 - 393, 2014/10
no abstracts in English
Ikeda, Shiro*; Kono, Hidetoshi
Tokei Suri, 61(1), p.135 - 146, 2013/06
no abstracts in English
Kono, Hidetoshi; Ikeda, Shiro*
Hoshako, 26(1), p.38 - 43, 2013/01
A new strong, short-pulse and coherent X-ray light source, which has been built at SPring8, is expected to achieve a single molecular imaging. With this 109 times brighter light than that of the current synchrotrons, we have to measure the diffraction within a few femto-second before the molecule is destroyed due to the radiation damage. Thus, the obtained diffraction pattern will be very sparse. We have recently developed a phase retrieval method based on the Bayesian statistics that is applicable for such a sparse diffraction pattern. In this article, we introduce the method.
Ikeda, Shiro*; Kono, Hidetoshi
Optics Express (Internet), 20(4), p.3375 - 3387, 2012/02
Times Cited Count:9 Percentile:44.4(Optics)Kinoshita, Hirohisa; Nohara, Tsuyoshi; Nakata, Takashi*; Ikeda, Yasutaka*; Ito, Kiyoshi*; Otsuki, Kenshiro*; Sagiya, Takeshi*; Takada, Keita*; Toda, Shinji*
Katsudanso Kenkyu, (25), p.27 - 37, 2005/06
Results of numerical analyses and field studies in the epicenter area of the 2000 Tottoriken-seibu earthquake suggest that several research techniques are effective for identifying subsurface active faults unaccompanied with remarkable surface earthquake faults. Field observation of the lineaments found in the area by detailed air-photo interpretation revealed that most of them are accompanied by faults and/or dikes, and some of them show minor slips at the time of the earthquake. Crustal deformation caused by the activity of the subsurface seismogenic faults is deduced by numerical analyses based on seismic and geodetic data. The vertical deformation assumed from the height changes of the terraces along the river across the epicenter area suggests that cumulative uplift and subsidence associated with left-lateral strike-slip has been continuing. Offsets rate of the streams and uplift rate of the river terraces surfaces show good agreement with the estimate from the parameter of the earthquake faults model. Identification of active faults without clear surface evidence before occurrence of earthquakes is a difficult issue, and the techniques adopted in this study will probably provide relevant information effective to locate subsurface active faults.
Isayama, Akihiko; Kamada, Yutaka; Hayashi, Nobuhiko; Suzuki, Takahiro; Oikawa, Toshihiro; Fujita, Takaaki; Fukuda, Takeshi; Ide, Shunsuke; Takenaga, Hidenobu; Ushigusa, Kenkichi; et al.
Nuclear Fusion, 43(10), p.1272 - 1278, 2003/10
Times Cited Count:130 Percentile:95.87(Physics, Fluids & Plasmas)no abstracts in English
Takada, Hiroshi; Maekawa, Fujio; Honmura, Shiro*; Yoshida, Katsuhiko*; Teraoku, Takuji*; Meigo, Shinichiro; Sakai, Akio*; Kasugai, Yoshimi; Kanechika, Shuji*; Otake, Hidenori*; et al.
Proceedings of ICANS-XVI, Volume 3, p.1115 - 1125, 2003/07
no abstracts in English
Nakamura, Hiroo; Tsuji, Shunji; ; Ozeki, Takahisa; Ishida, Shinichi; Azumi, Masafumi; Akiba, Masato; Ando, Toshiro; Fujii, Tsuneyuki; Fukuda, Takeshi; et al.
Nuclear Fusion, 30(2), p.235 - 250, 1990/02
Times Cited Count:16 Percentile:53.47(Physics, Fluids & Plasmas)no abstracts in English
Nakamura, Hiroo; Tsuji, Shunji; ; Ozeki, Takahisa; Ishida, Shinichi; Azumi, Masafumi; Akiba, Masato; Ando, Toshiro; Fujii, Tsuneyuki; Fukuda, Takeshi; et al.
JAERI-M 89-106, 52 Pages, 1989/08
no abstracts in English
Kikuchi, Mitsuru; Ando, Toshiro; Araki, Masanori; ; Horiike, Hiroshi; Ikeda, Yoshitaka; ; Koizumi, Koichi; Matsukawa, Makoto; ; et al.
Fusion Technology 1988, p.287 - 292, 1989/00
no abstracts in English
Matsukawa, Makoto; Ando, Toshiro; Araki, Masanori; ; Horiike, Hiroshi; Ikeda, Yoshitaka; Kikuchi, Mitsuru; ; Koizumi, Koichi; ; et al.
Fusion Technology 1988, p.293 - 297, 1989/00
no abstracts in English
Fujii, Tsuneyuki; Kimura, Haruyuki; Saigusa, Mikio; Akiba, Masato; Ando, Toshiro; ; Aoyagi, Tetsuo; ; Azumi, Masafumi; Fukuda, Takeshi; et al.
Plasma Physics and Controlled Nuclear Fusion Research 1988, Vol.1, p.605 - 610, 1989/00
no abstracts in English
Hotokezaka, Hiroyasu*; Ban, Yasutoshi; Ikeda, Hidematsu*; Harada, Masayuki*; Mizuguchi, Koji*; Saso, Michitaka*; Sugai, Hiroshi*; Tokeshi, Manabu*; Ikeda, Yasuhisa*; Morita, Yasuji; et al.
no journal, ,
The following items were studied for developing innovative equipment for analysis that provides high-sensitivity and rapid analysis for ultra small amount of samples utilizing microchip and thermal lens detector: Optimum flow condition for forming two-phase steady laminar flow in micro channel, applicability of thermal lens detector for U(VI) and H concentration analysis, extraction properties of U(VI) from aqueous phase to organic phase in micro channel, and radiation resistance of microchips and capillary tubes. In this presentation the summary of these items are reported.
Nogawa, Norio*; Ikeda, Keishiro*; Morikawa, Naotake*; Motoishi, Shoji; Matsuoka, Hiromitsu; Hashimoto, Kazuyuki
no journal, ,
Rhenium-186(T=90h; E
=1.1 MeV; E
=137 keV) and rhenium-188(T
=17h; E
=2.1 MeV; E
=153 keV) are
particle emitting radionuclides with excellent properties for targeted radiotherapy. Re-188 has the advantages associated with carrier-free, generator-produced radionuclides. PZC generator with many tungsten molecules is expected for as practical generator. This generator was experimented for clarifying a characteristic. Meso-2,3-dimercaptosuccinic acid (DMSA) is applied for palliative treatment of pain associated with disease. Effect of pH is studied on preparation of
Re-DMSA.