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Journal Articles

Bibliometric study of radiation application on microdose useful for new drug development

Komoda, Fumio*; Suzuki, Akiko*; Yanagisawa, Kazuaki; Inoue, Tomio*

Annals of Nuclear Medicine, 23(10), p.829 - 841, 2009/12

 Times Cited Count:1 Percentile:7.62(Radiology, Nuclear Medicine & Medical Imaging)

The number of newly approved medicines for market decreased because of the great disparity between animal model in pre-clinical trial and human model in clinical trial. This bottleneck may be expected to be gotten rid of by change in paradigm of drug development based on microdosing, which is enabled by radiation related imaging technology. However, this is impossible without being accompanied by interdisciplinary joint researches, in which clinical investigators belonging to medical schools or hospitals play the most decisive role. In this article, authors verify based on bibliometrics that Japan has not employed the opportunity for revitalizing drug research activities because Japanese researchers' attitude towards radiation technology may not be so positive in comparison with the US, and because the role which clinical investigators play in the phase of pre-clinical trial is smaller in Japan than in the U.S.A..

Journal Articles

Economic scale of utilization of radiation in medicine in Japan

Yanagisawa, Kazuaki; Inoue, Tomio*; Hayakawa, Kazushige*; Shiotari, Harutaka*; Nakamura, Yoshihide*; Matsuyama, Kazuya*; Nagasawa, Kiyoshi*

Applied Radiation and Isotopes, 67(7-8), p.1387 - 1391, 2009/06

 Times Cited Count:1 Percentile:10.66(Chemistry, Inorganic & Nuclear)

Economic scale of radioisotopes (RI) in Japan is studied in the field of medicine, agriculture and a part of industry. (1) RI is used during medical examination with economic scale by 1.7M (million) dollars in 1997 and 0.4M dollars in 2005. (2) Economic scale of RI utilization in agriculture is 4M dollars for R&D, 127M dollars for environmental protection and 1M dollars for chronology. A total sum is 132M dollars for 2005 and 24M dollars for 1997. RI usage in agriculture is increased 5 times due to needs at environmental technology lasted after the Kyoto protocol. (3) Indirect economic scale of RI ($$^{85}$$Kr, $$^{147}$$Pm, $$^{90}$$Cr) usage in paper fabrication field in Japan for 2006 is 8,432M dollars.

Journal Articles

Inheritance from low-level radioactive waste

Yanagisawa, Kazuaki; Kume, Tamikazu*; Makuuchi, Keizo*; Inoue, Tomio*; Komoda, Fumio*; Maeda, Mitsuru*

Dekomisshoningu Giho, (39), p.44 - 61, 2009/03

A benefit born as an inheritance from disposed low level radioactive waste is considered. In the present study, a direct economic scale of application of radiation in Japanese industry, agriculture and medicine is taken as parameter for quantifying the size of benefit. In 2006, the economic scale is about 21 billion dollars for industry, 2.5 billion dollars for agriculture and 14 billion dollars for medicine. Economic scale covered the all fields is totaled 37 billion dollars. Due to those benefit, one can drive a car and play an internet, pleasure the dinning food. Diagnosis and treatment by nuclear medicine can possible to survive the millions of lives and resulting in improving the quality of life, decreasing pain and suffering. However, most Japanese (more than 80%) may not aware those benefits to date. This report is prepared for aiming at disseminating those benefits to our peoples.

Journal Articles

Application of radiation in nuclear medicine, charged particle therapy and BNCT in Japan

Yanagisawa, Kazuaki; Inoue, Tomio*; Hayakawa, Kazushige*; Shiotari, Harutaka*; Nakamura, Yoshihide*; Matsuyama, Kazuya*; Nagasawa, Kiyoshi*

Proceedings of 4th International Symposium on Radiation Education (ISRE 2008), p.3_16 - 3_20, 2008/12

The economic scale of radiological technologies applied to medical reimbursement is 14 billion dollars in 2005, which is larger by a factor of 17% than that of 1997. The value corresponds to about 4 to 8% (4.4% for medicine and 0.4% for dentistry) of the national health expenditure (301 billion dollars). The economic scale of radiation application at FDGPET and the charged particle therapy is 74 million dollars and 24 million dollars in 2005. In 1997 it was only 2 million dollars for the former and zero for the latter. The radiation technologies in these fields are rapidly developing. FDGPET enhanced the survival of 50,558 patients. Charged particle therapy enhanced the survival of 927 patients at 4 specified hospitals and 5,229 patients at the Proton Medical Research Center University of Tsukuba. Radiological technology is quite beneficial for the improvement of Japanese people's quality of life (QOL).

Journal Articles

Economic scale of nuclear application

Saito, Shinzo*; Tanaka, Ryuichi*; Kume, Tamikazu; Inoue, Tomio*; Takahashi, Shoji*

Genshiryoku eye, 54(5), p.34 - 41, 2008/05

no abstracts in English

Journal Articles

An Economic index regarding market creation of products obtained from utilization of radiation and nuclear energy, 4; Comparison between Japan and U. S. A.

Yanagisawa, Kazuaki; Kume, Tamikazu; Makuuchi, Keizo; Tagawa, Seiichi*; Chino, Mitsuo*; Inoue, Tomio*; Takehisa, Masaaki*; Hagiwara, Miyuki*; Shimizu, Masahiko*

Journal of Nuclear Science and Technology, 39(10), p.1120 - 1124, 2002/10

 Times Cited Count:3 Percentile:24.2(Nuclear Science & Technology)

no abstracts in English

Journal Articles

Economic scale of utilization of radiation, 3; Medicine: Comparison between Japan and the U. S. A.

Inoue, Tomio*; Hayakawa, Kazushige*; Shiotari, Harutaka*; Takada, Eiichi*; Torikoshi, Masami*; Nagasawa, Kiyoshi*; Hagiwara, Kazuo*; Yanagisawa, Kazuaki

Journal of Nuclear Science and Technology, 39(10), p.1114 - 1119, 2002/10

 Times Cited Count:4 Percentile:30.15(Nuclear Science & Technology)

no abstracts in English

Journal Articles

Economic scale of utilization of nuclear

Takehisa, Masaaki*; Tagawa, Seiichi*; Kashiwagi, Masayuki*; Tominaga, Hiroshi*; Ishikawa, Isamu*; Ooka, Norikazu; Kamada, Toshimitsu*; Hosobuchi, Kazunari*; Makuuchi, Keizo; Takeshita, Hidefumi; et al.

Genshiryoku Riyo No Keizai Kibo; NSA/Commentaries, No.9, 139 Pages, 2001/01

no abstracts in English

Journal Articles

Hybrid monitoring system for high temperature gas cooling reactor

Nabeshima, Kunihiko; Tuerkcan, E.*; Suzudo, Tomoaki; Nakagawa, Shigeaki; Inoue, K.*; Oono, Tomio*; *; Suzuki, Katsuo

Proc. of Human-Computer Interaction International'99, 2, p.1187 - 1191, 1999/00

no abstracts in English

Oral presentation

Application of radiological technology to medical device advancements in Japan

Yanagisawa, Kazuaki; Inoue, Tomio*; Hayakawa, Kazushige*; Shiotari, Harutaka*; Nakamura, Yoshihide*; Matsuyama, Kazuya*; Nagasawa, Kiyoshi*

no journal, , 

Our economic study performed in 1997 revealed that the use of radiological technology in medicine was tended to spread. A reimbursement of medicine was about 10 billion dollars corresponding to about 4% of the national health expenditures (240 billion dollars) or to an average expenditure of 1,900 dollars a year for the Japanese. In 2005 it was about 13 billion dollars. An increasing rate was 17%. One of main cause of this increase is a significant advancement of medical devices represented by digital-X ray, multi-slice CT, PET and PET-CT.

Oral presentation

Economic scale of utilization of radiation in medicine; National health expenditures

Yanagisawa, Kazuaki; Inoue, Tomio*; Hayakawa, Kazushige*; Shiotari, Harutaka*; Nakamura, Yoshihide*; Matsuyama, Kazuya*; Nagasawa, Kiyoshi*

no journal, , 

The economic scale of radiological technology in medicine/dentistry in 2005 was about 13 billion dollars. Economic scale of medical/dental cares in 2005 was large to the magnitude of 17% than that in 1997. It is worthy of mentioning that almost radiological items used in medical/dental cares were increased except a radioisotope examination in medical care. Namely, radioisotope examination was 1.7 million dollars in 1997 but was 0.4 million dollars in 2005. No radioisotopes were used in the examination of dentist.

Oral presentation

Economic effect of radiological application; Year 2006

Yanagisawa, Kazuaki; Kume, Tamikazu; Makuuchi, Keizo*; Inoue, Tomio*; Komoda, Fumio*; Maeda, Mitsuru*

no journal, , 

Products produced by using radiological application (electron and $$gamma$$ ray etc.) at industrial and agricultural fields as well as reimbursement of medical and dental cares in Japanese market was studied at fiscal year 2006. This is to certify the quantitative role of radiological application, which will benefit the welfare of the people of our nation. The shipment of semiconductor has the largest share in our industrial market, having economic scale approximately of 4,800 billion yen. The net value taking into consideration of attributed ratio of radiation as much as 23% will be 1,082 billion yen. The shipment of rice born by mutation has the largest share in our agricultural market (90% of the total), having economic scale approximately of 260 billion yen. Application of radiation is done at medical and dentistry fields, an economic scale based on reimbursement is 1,620 billion yen.

Oral presentation

Application of radiation in medicine in Japan

Yanagisawa, Kazuaki; Inoue, Tomio*; Hayakawa, Kazushige*; Shiotari, Harutaka*; Nakamura, Yoshihide*; Matsuyama, Kazuya*; Nagasawa, Kiyoshi*

no journal, , 

For Japan, application of radiation in nuclear medicine is prominently used for the diagnosis, the radiotherapy and the examination by radioisotopes (RI). They addressed to FDG-PET, charged particle therapy and BNCT at the specified hospitals. Incomes are reimbursed by a national health insurance. In 2005, reimbursed incomes at those hospitals were studied as an economic scale as a commissioned work from the Cabinet Office, Government of Japan. Results were directly compared with those from previous work done in 1997. The economic scale of the application of radiation to all medical reimbursement in our country is 14 billion dollars, which is larger by a factor of 17% than that of 1997. The value corresponds to about 4.8% of the national health expenditure (301billion dollars), consisting of 4.4% for medicine and 0.4% for dentistry.

13 (Records 1-13 displayed on this page)
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