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Journal Articles

Experimental verification of models assessing Eh evolution induced by corrosion of carbon steel overpack

Sakamaki, Keiko; Kataoka, Masaharu; Maeda, Toshikatsu; Iida, Yoshihisa; Kamoshida, Michio; Yamaguchi, Tetsuji; Tanaka, Tadao

Corrosion Engineering, Science and Technology, 49(6), p.450 - 454, 2014/09

 Times Cited Count:0 Percentile:0.01(Materials Science, Multidisciplinary)

Corrosion experiments of a carbon steel plate embedded in bentonite mixture were conducted toverify our models assessing Eh evolution induced by corrosion of carbon steel overpack. Theexperimental results showed that the Eh decreased for the first 200 days and was subsequentlystabilised at around -450 mV; corrosion products were identified as magnetite and Fe waspresent mostly as divalent Fe within a 5 mm range from the carbon steel plate. Reactive transportmodelling was performed to assess the Eh evolution in the system using kinetic dissolution modelfor metallic iron and thermodynamic equilibrium models for other chemical reactions and closelyreproduced the experimental results. The models were verified only under the conditionsemployed in this study.

JAEA Reports

Animal study on biological responses by radon inhalation making use of waste rock which contains feeble activity of uranium (Joint research)

Ishimori, Yuu; Sakoda, Akihiro; Tanaka, Hiroshi; Mitsunobu, Fumihiro*; Yamaoka, Kiyonori*; Kataoka, Takahiro*; Yamato, Keiko*; Nishiyama, Yuichi*

JAEA-Research 2013-005, 60 Pages, 2013/06

JAEA-Research-2013-005.pdf:4.49MB

Okayama University and the Japan Atomic Energy Agency (JAEA) have carried out the collaborative study of physiological effects of inhaled radon for the low-dose range. From 2007 to 2011, the following results were obtained. (1) Literature on effects of radon for the low-dose range was surveyed to determine the present tasks. (2) The first Japanese large-scale facility was developed for radon inhalation experiments with small animals. (3) Relationships between radon concentration and inhalation time were widely examined to understand the change in antioxidative functions due to radon, which are the most basic parameters. (4) Inhibitory effects of radon on oxidative damages were observed using model mice with reactive oxygen- or free radical-related diseases like alcohol-induced oxidative damages and type I diabetes. (5) In order to discuss biological responses quantitatively following radon inhalation, the biokinetics of inhaled radon was examined and the model for calculation of absorbed doses for organs and tissues was obtained.

Journal Articles

Studies on possibility for alleviation of lifestyle diseases by low-dose irradiation or radon inhalation

Kataoka, Takahiro*; Sakoda, Akihiro*; Yoshimoto, Masaaki*; Nakagawa, Shinya*; Toyota, Teruaki*; Nishiyama, Yuichi*; Yamato, Keiko*; Ishimori, Yuu; Kawabe, Atsushi*; Hanamoto, Katsumi*; et al.

Radiation Protection Dosimetry, 146(1-3), p.360 - 363, 2011/07

 Times Cited Count:5 Percentile:42.62(Environmental Sciences)

Our previous studies showed the possibility that activation of the antioxidative function alleviates various oxidative damages, which are related to lifestyle diseases. Results showed that, low-dose X-ray irradiation activated superoxide dismutase and inhibits oedema following ischaemia-reperfusion. To alleviate ischaemia-reperfusion injury with transplantation, the changes of the antioxidative function in liver graft using low-dose X-ray irradiation immediately after exenteration were examined. Results showed that liver grafts activate the antioxidative function as a result of irradiation. In addition, radon inhalation enhances the antioxidative function in some organs, and alleviates alcohol-induced oxidative damage of mouse liver. Moreover, in order to determine the most effective condition of radon inhalation, mice inhaled radon before or after carbon tetrachloride (CCl$$_{4}$$) administration. Results showed that radon inhalation alleviates CCl$$_{4}$$-induced hepatopathy, especially prior inhalation. It is highly possible that adequate activation of antioxidative functions induced by low-dose irradiation can contribute to preventing or reducing oxidative damages, which are related to lifestyle diseases.

Journal Articles

The Small-molecule Bcl-2 inhibitor HA14-1 sensitizes cervical cancer cells, but not normal fibroblasts, to heavy-ion radiation

Hamada, Nobuyuki*; Kataoka, Keiko*; Sora, Sakura*; Hara, Takamitsu*; Omura, Motoko*; Funayama, Tomoo; Sakashita, Tetsuya; Nakano, Takashi*; Kobayashi, Yasuhiko

Radiotherapy and Oncology, 89(2), p.227 - 230, 2008/11

 Times Cited Count:8 Percentile:31.07(Oncology)

Oral presentation

Overcoming the radioresistance of tumor cells with carbon ions

Hamada, Nobuyuki*; Hara, Takamitsu*; Kataoka, Keiko*; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

Heavy-ion irradiation overcomes the radioresistance of tumor cells overexpressing Bcl-2

Hamada, Nobuyuki*; Hara, Takamitsu*; Funayama, Tomoo; Sakashita, Tetsuya; Kataoka, Keiko*; Sora, Sakura; Suzuki, Michiyo; Fukamoto, Kana; Yokota, Yuichiro; Omura, Motoko*; et al.

no journal, , 

no abstracts in English

Oral presentation

Exposure of normal human diploid fibroblasts to heavy ions accelerate differentiation in their progeny

Sora, Sakura; Hamada, Nobuyuki*; Hara, Takamitsu*; Funayama, Tomoo; Sakashita, Tetsuya; Kataoka, Keiko*; Suzuki, Michiyo; Fukamoto, Kana; Yokota, Yuichiro; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

Bystander effect studies using heavy-ion microbeam at JAEA-Takasaki

Kobayashi, Yasuhiko; Funayama, Tomoo; Sakashita, Tetsuya; Furusawa, Yoshiya*; Shao, C.*; Hamada, Nobuyuki*; Wada, Seiichi*; Yokota, Yuichiro; Kakizaki, Takehiko*; Fukamoto, Kana; et al.

no journal, , 

Oral presentation

Effects of $$gamma$$-ray irradiation on the basal slowing response in ${it Caenorhabditis elegans}$

Suzuki, Michiyo; Sakashita, Tetsuya; Funayama, Tomoo; Fukamoto, Kana; Hamada, Nobuyuki*; Yokota, Yuichiro; Kataoka, Keiko*; Sora, Sakura; Tsuji, Toshio*; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

Overcoming the radioresistance of Bcl-2 overexpressing tumor cells with heavy-ion irradiation

Hamada, Nobuyuki*; Hara, Takamitsu*; Funayama, Tomoo; Sakashita, Tetsuya; Kataoka, Keiko*; Sora, Sakura; Suzuki, Michiyo; Fukamoto, Kana; Yokota, Yuichiro; Omura, Motoko*; et al.

no journal, , 

no abstracts in English

Oral presentation

HA14-1, an inhibitor of Bcl-2, may sensitize tumor cells to heavy ions

Kataoka, Keiko*; Hamada, Nobuyuki*; Funayama, Tomoo; Sakashita, Tetsuya; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

Heavy ion-induced differentiation of normal human fibroblasts

Sora, Sakura; Hamada, Nobuyuki*; Kataoka, Keiko*; Kobayashi, Yasuhiko; Sakashita, Tetsuya; Funayama, Tomoo

no journal, , 

no abstracts in English

Oral presentation

HA14-1, an inhibitor of Bcl-2, may sensitize tumor cells to heavy ions

Kataoka, Keiko*; Hamada, Nobuyuki*; Sora, Sakura; Kobayashi, Yasuhiko; Sakashita, Tetsuya; Funayama, Tomoo

no journal, , 

no abstracts in English

Oral presentation

Overcoming the radioresistance of Bcl-2 overexpressing tumor cells with heavy-ion irradiation

Hamada, Nobuyuki*; Hara, Takamitsu*; Funayama, Tomoo; Sakashita, Tetsuya; Kataoka, Keiko*; Sora, Sakura; Omura, Motoko*; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

HA14-1, an inhibitor of Bcl-2, may sensitize tumor cells to heavy ions

Kataoka, Keiko*; Hamada, Nobuyuki*; Funayama, Tomoo; Sakashita, Tetsuya; Sora, Sakura; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

Bcl-2 as a potential target for heavy-ion therapy

Hamada, Nobuyuki*; Hara, Takamitsu*; Kataoka, Keiko*; Sora, Sakura*; Omura, Motoko*; Funayama, Tomoo; Sakashita, Tetsuya; Yokota, Yuichiro; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

HA14-1, an inhibitor of Bcl-2, may sensitize tumor cells to heavy ions

Hamada, Nobuyuki*; Kataoka, Keiko*; Sora, Sakura*; Hara, Takamitsu*; Funayama, Tomoo; Sakashita, Tetsuya; Omura, Motoko*; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

The Bcl-2 as an attractive target to improve the efficiency of heavy-ion therapy

Hamada, Nobuyuki*; Hara, Takamitsu*; Kataoka, Keiko*; Sora, Sakura*; Funayama, Tomoo; Sakashita, Tetsuya; Yokota, Yuichiro; Omura, Motoko*; Kobayashi, Yasuhiko

no journal, , 

no abstracts in English

Oral presentation

Experimental verification of a code assessing Eh evolution induced by corrosion of carbon steel overpack

Sakamaki, Keiko; Otsuka, Ichiro*; Iida, Yoshihisa; Inada, Daisuke*; Kamoshida, Michio; Kataoka, Masaharu; Yamaguchi, Tetsuji; Tanaka, Tadao

no journal, , 

no abstracts in English

19 (Records 1-19 displayed on this page)
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