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Kusano, Kanya*; Ichimoto, Kiyoshi*; Ishii, Mamoru*; Miyoshi, Yoshizumi*; Yoden, Shigeo*; Akiyoshi, Hideharu*; Asai, Ayumi*; Ebihara, Yusuke*; Fujiwara, Hitoshi*; Goto, Tadanori*; et al.
Earth, Planets and Space (Internet), 73(1), p.159_1 - 159_29, 2021/12
Times Cited Count：6 Percentile：49.29(Geosciences, Multidisciplinary)The PSTEP is a nationwide research collaboration in Japan and was conducted from April 2015 to March 2020, supported by a Grant-in-Aid for Scientific Research on Innovative Areas from the Ministry of Education, Culture, Sports, Science and Technology of Japan. It has made a significant progress in space weather research and operational forecasts, publishing over 500 refereed journal papers and organizing four international symposiums, various workshops and seminars, and summer school for graduate students at Rikubetsu in 2017. This paper is a summary report of the PSTEP and describes the major research achievements it produced.
Tamada, Taro; Shinmi, Daisuke*; Ikeda, Masahiro*; Yonezawa, Yasushi*; Kataoka, Shiro*; Kuroki, Ryota; Mori, Eiji*; Motoki, Kazuhiro*
Scientific Reports (Internet), 5, p.17936_1 - 17936_12, 2015/12
Times Cited Count：25 Percentile：63.17(Multidisciplinary Sciences)The fully human monoclonal antibody KMTR2 acts as a strong direct agonist for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor 2 (TRAIL-R2), which is capable of inducing apoptotic cell death without cross-linking. To investigate the mechanism of direct agonistic activity induced by KMTR2, the crystal structure of the extracellular region of TRAIL-R2 and a Fab fragment derived from KMTR2 (KMTR2-Fab) was determined to 2.1 
resolution. Two KMTR2-Fabs assembled with the complementarity-determining region 2 of the light chain via two-fold crystallographic symmetry, suggesting that the KMTR2-Fab assembly tended to enhance TRAIL-R2 oligomerization. A single mutation at Asn53 to Arg located at the two-fold interface in the KMTR2 resulted in a loss of its apoptotic activity, although it retained its antigen-binding activity. These results indicate that the strong agonistic activity, such as apoptotic signaling and tumor regression, induced by KMTR2 is attributed to TRAIL-R2 superoligomerization induced by the interdimerization of KMTR2.
Sato, Tatsuhiko; Kataoka, Ryuho*; Yasuda, Hiroshi*; Yashiro, Seiji*; Kuwabara, Takao*; Shiota, Daiko*; Kubo, Yuki*
Radiation Protection Dosimetry, 161(1-4), p.274 - 278, 2014/10
Times Cited Count：22 Percentile：85.07(Environmental Sciences)We applied our simulation technique to the analysis of air shower induced by mono-energetic protons and alpha particles, which are the dominant component of SEP. The results of the simulations were summarized in a database containing particle fluxes for each condition as a function of the atmospheric depth. This database was then incorporated into our developing Warning System of AVIation Exposure to SEP called WASAVIES. In this system, the aircrew doses due to SEP exposure are estimated within 6 hours after the flare onset, using the established database multiplied with the SEP fluxes incident to the earth. The MHD Cube model is employed in the determination of the incident SEP fluxes. The procedures for the air shower simulation together with some initial results of the aircrew dose calculations for past ground-level enhancement (GLE) events will be presented at the meeting.
Kataoka, Ryuho*; Sato, Tatsuhiko; Kubo, Yuki*; Shiota, Daiko*; Kuwabara, Takao*; Yashiro, Seiji*; Yasuda, Hiroshi*
Space Weather, 12(6), p.380 - 386, 2014/06
Times Cited Count：19 Percentile：51.52(Astronomy & Astrophysics)Solar energetic particles (SEP) sometimes induce air shower that significantly increase the radiation dose at flight altitudes. In order to inform the situation of such a space radiation hazard to aircrews, a physics-based forward model is developed as WASAVIES (Warning System for Aviation Exposure to SEP) based on the focused transport equation and Monte Carlo particle transport simulation of the air shower. WASAVIES gives the fastest and simplest way to predict the time profile of dose rate during ground-level enhancements (GLEs).
Sato, Tatsuhiko; Yasuda, Hiroshi*; Kataoka, Ryuho*; Yashiro, Seiji*; Kuwabara, Takao*; Shiota, Daiko*
no journal, ,
In order to precisely estimate the aircrew doses, the Monte Carlo simulation for air shower is indispensable. We had therefore simulated air showers induced by GCR, using a general-purpose Monte Carlo particle and heavy ion transport simulation code system PHITS, and established a model for calculating the aircrew doses anywhere in the world at the solar quiet time. In this study, we applied our simulation technique to the analysis of air shower induced by SEP, and established a model for estimating the aircrew doses from a given SEP energy spectrum and cutoff latitude. The model is to be incorporated into our developing Warning System of AVIation Exposure to SEP called WASAVIES.
Sato, Tatsuhiko; Kataoka, Ryuho*; Yasuda, Hiroshi*; Yashiro, Seiji*; Kuwabara, Takao*; Shiota, Daiko*
no journal, ,
We are trying to develop a two-step forecast system for the SEP doses named WASAVIES (WArning System of AVIation Exposure to SEP). The present status of the development of WASAVIES will be reported at the meeting, together with a brief summary of the currently operating systems for estimating the GCR and SEP doses.
Sato, Tatsuhiko; Yasuda, Hiroshi*; Kataoka, Ryuho*; Yashiro, Seiji*; Kuwabara, Takao*; Shiota, Daiko*
no journal, ,
When solar energetic particles (SEP) are incident to the atmosphere, they can induce air showers by generating varieties of secondary particles. Such secondary particles can reach conventional flight altitudes (12 km), and hence, aircrews are exposed to enhanced level of radiations. In order to precisely estimate the aircrew doses, the Monte Carlo simulation for air shower is indispensable. We therefore simulated air showers induced by mono-energetic protons, using a general-purpose Monte Carlo particle and heavy ion transport simulation code system PHITS, and developed a database of particle fluxes in the atmosphere. Combining the database with the proton fluxes measured by PAMELA during the GLE event occurred on Dec. 13th 2006, the count rates of the neutron monitor located at Thule were calculated. The calculated count rates agree with the measured data fairly well, verifying the accuracy of our simulation technique.
Tashiro, Shinsuke; Matsumoto, Tetsuya; Kataoka, Osamu; Amano, Yuki; Abe, Hitoshi; Yamane, Yuichi; Yoshida, Kazuo; Ishikawa, Jun; Uchiyama, Gunzo; Ueda, Yoshinori*; et al.
no journal, ,
Measurements on the release ratios of aerial radioactive materials from mocked fuel reprocessing liquid waste under its boiling to dryness process were performed using labo-scaled experiments. Test sample, dissolved 27 elements into nitric acid and arranged to 2M acidity, was heated up to 300 
C under the constant air ventilation. Steam, gaseous and airborne materials were collected or absorbed at the condenser, the air filter and the washing bottles. The accumulated release ratios of mocked FP elements from samples were determined using ICP-MS. From the accumulated release ratios determined from the condensed samples, the major release of Cs and Ru could be involved the release of mist and gaseous RuO
, respectively. Besides, accumulated release ratios of Ru was about 10 to 1000 times higher than Cs, differed from the literature using fuel reprocessing liquid waste. Its differences could be influenced the nitrous acid, which was reduced the generation of RuO.
Tashiro, Shinsuke; Matsumoto, Tetsuya; Kataoka, Osamu; Amano, Yuki; Abe, Hitoshi; Yamane, Yuichi; Yoshida, Kazuo; Ishikawa, Jun; Uchiyama, Gunzo; Ueda, Yoshinori*; et al.
no journal, ,
The release behavior of radioactive materials from high-level radioactive liquid wastes (HLW) from reprocessing plants under an accidents of boiling to dryness of HLW condition has been studied. The influences of FP concentration in the simulated HLW on the release ratio of FP from the waste were measured in the laboratory-scaled experiments using non-radioactive simulated HLW which was prepared by dissolving 27 FP elements into nitric acid and adjusted to 2 M acidity. The simulated HLW was heated up to 300C under the constant air ventilation condition. The accumulated release ratios of FP elements from samples were determined using ICP-MS analysis. It was found that the accumulated release ratio of Ru was decreased with the increase of the initial Ru concentration in the simulated HLW. However, those of Cs and Nd were not influenced by the initial concentrations of them.
Sato, Tatsuhiko; Yasuda, Hiroshi*; Kataoka, Ryuho*; Yashiro, Seiji*; Kuwabara, Takao*; Shiota, Daiko*; Kubo, Yuki*
no journal, ,
When solar energetic particles (SEP) are incident to the atmosphere, they can induce air showers by generating varieties of secondary particles. Such secondary particles can reach the deep into the atmosphere, and enhance the level of radiation doses. This can be a hazard of aircrews. In order to precisely estimate the radiation doses during large solar particle events, we are developing a warning system of aviation exposure to SEP, WASAVIES. The WASAVIES has been tested and verified by making a comparison between the measured and calculated count rates of several neutron monitors during past GLE (ground level enhancement) events. The final goal of our project is to predict the enhancement of radiation doses due to SEP exposure within 6 hours from the GLE onset.
Miyamoto, Masanori; Shirozu, Hidetomo; Morita, Minoru; Fujisaku, Sakae; Kurita, Tsutomu; Kimura, Yuichi; Kataoka, Satoshi; Seya, Katsunori*; Sasaki, Shunichi
no journal, ,
no abstracts in English
Kataoka, Shoji; Takano, Masato; Nagayama, Mineo; Kano, Yoshiharu*; Suzuki, Tatsuya*; Miyabe, Shinsuke*; Sakuma, Takashi*; Shirozu, Hidetomo
no journal, ,
no abstracts in English
Sato, Fuminori; Kataoka, Shoji; Matsushima, Ryotatsu; Otake, Katsumi*; Shirozu, Hidetomo
no journal, ,
no abstracts in English
Sato, Fuminori; Kataoka, Shoji; Matsushima, Ryotatsu; Otake, Katsumi*; Shirozu, Hidetomo
no journal, ,
no abstracts in English
Sato, Fuminori; Kataoka, Shoji; Suzuki, Tatsuya*; Miyabe, Shinsuke*; Sakuma, Takashi*; Shirozu, Hidetomo
no journal, ,
Cs and Sr adsorbents used in LWTF is studied. In this report results of the Cs and Sr adsorption tests were analyzed and examined for application to LWTF.
Kataoka, Shoji; Tsunoda, Hiroki; Matsushima, Ryotatsu; Sato, Fuminori; Shirozu, Hidetomo
no journal, ,
Low Active Waste Treatment Development Facility (LWTF) in Tokai Reprocessing Plant (TRP) is a facility for treatment of low-radioactive liquid and solid wastes generated from the TRP. The liquid wastes treated in LWTF are concentrated low-radioactive liquid waste and phosphoric acid solution, and they are planned to be solidified with cement in our new equipment. The concentrated liquid wastes are separated into slurry and carbonate compounds by a nuclide separation equipment currently in LWTF and a nitrate decomposition equipment which is under development, and then the cement solidification will be carried out on each liquid waste. Currently, studying and designing for the introduction of the nitrate decomposition equipment and cement solidification equipment is in progress. In this paper, results of the cementation demonstration on simulated waste liquids of the carbonate, phosphoric acid and slurry are reported.
