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Journal Articles

Innate immune genes including a mucin-like gene, ${it mul-1}$, induced by ionizing radiation in ${it Caenorhabditis elegans}$

Kimura, Takafumi*; Takanami, Takako*; Sakashita, Tetsuya; Wada, Seiichi*; Kobayashi, Yasuhiko; Higashitani, Atsushi*

Radiation Research, 178(4), p.313 - 320, 2012/10

 Times Cited Count:6 Percentile:39.9(Biology)

Here, we found that exposure to ionizing radiation (IR) induce certain innate immune response gene of ${it mul-1}$ in the intestine. Pre-treatment with IR before seeding on ${it Pseudomonas aeruginosa}$ lawn plate, significantly increased survival rate in the nematode. IR induction of ${it mul-1}$ gene was highly dependent on the ELT-2 transcription factor and p38 MAPK. Moreover, the insulin/IGF-1 signal pathway works as an enhancer of induction of this gene. Silencing of the ${it mul-1}$ gene led to growth retardation after IR irradiation. Finally, we describe the cross-tolerance between the responses to radiation exposure and innate immune system.

Journal Articles

Radiation biology of ${it Caenorhabditis elegans}$; Germ cell response, aging and behavior

Sakashita, Tetsuya; Takanami, Takako*; Yanase, Sumino*; Hamada, Nobuyuki*; Suzuki, Michiyo; Kimura, Takafumi*; Kobayashi, Yasuhiko; Ishii, Naoaki*; Higashitani, Atsushi*

Journal of Radiation Research, 51(2), p.107 - 121, 2010/03

 Times Cited Count:27 Percentile:61.15(Biology)

The study of radiation effect in ${it Caenorhabditis (C.) elegans}$ have been carried out over three decades and now allow for understanding at the molecular, cellular and individual levels. This review describes the current knowledge of the biological effects of ionizing irradiation with a scope of the germ line, aging and behavior. ${it C. elegans}$ may be a good ${it in vivo}$ model system in the field of radiation biology.

Journal Articles

Fuel performance evaluation of rock-like oxide fuels

Shirasu, Noriko; Kuramoto, Kenichi; Nakano, Yoshihiro; Yamashita, Toshiyuki; Kimura, Yasuhiko; Nihei, Yasuo; Ogawa, Toru

Journal of Nuclear Materials, 376(1), p.88 - 97, 2008/05

 Times Cited Count:13 Percentile:68.01(Materials Science, Multidisciplinary)

The concept of the rock-like oxide (ROX) fuel has been developed for the annihilation of excess plutonium in light water reactors. Irradiation tests and post-irradiation examinations were carried out on candidate ROX fuels. The ternary fuel of YSZ-spinel-corundum system, the single-phase fuels of YSZ, the particle dispersed fuels of YSZ in spinel or corundum matrix, and the blended fuels of YSZ and spinel or corundum matrix were fabricated and submitted to irradiation tests. The fuels containing spinel showed chemical instabilities with the vaporization of MgO component, which caused fuel restructuring. The swelling behavior was improved with the particle-dispersed fuels. However, the particle-dispersed fuels showed higher fractional gas release (FGR) than blended type fuels. The FGR of YSZ single-phase fuels were comparable to what would be expected for UO$$_{2}$$ fuels. The YSZ single-phase fuel showed the best irradiation performance among the ROX fuels investigated.

Journal Articles

Preparation of acellular arteries by $$gamma$$ irradiation

Fujisato, Toshiya*; Kikuchi, Masahiro; Sakashita, Tetsuya; Funayama, Tomoo; Kobayashi, Yasuhiko; Funamoto, Seiichi*; Kimura, Tsuyoshi*; Kishida, Akio*; Yamaoka, Tetsuji*

JAEA-Review 2007-060, JAEA Takasaki Annual Report 2006, P. 119, 2008/03

Synthetic materials, such as ePTFE or Dacron are not suitable for reconstructing the small-diameter arteries. In contrast, tissue engineering (TE) graft has been attracting great attention recently. One of the promising approaches of TE grafts is using acellular tissues. The acellular scaffold may have the same structure and characteristics as the natural tissue and can be replaced with the host tissues. In this study, we prepared the acellular scaffold using $$gamma$$ irradiation, which is expected to induce the apoptosis of the cells.

Journal Articles

Effect of energetic heavy-ion irradiation on gene expression in ${it Caenorhabdits elegans}$

Higashitani, Atsushi*; Mori, Chihiro*; Kimura, Takafumi*; Ikenaga, Takahiko*; Takanami, Takako*; Sakashita, Tetsuya; Wada, Seiichi*; Hamada, Nobuyuki*; Kobayashi, Yasuhiko

JAEA-Review 2007-060, JAEA Takasaki Annual Report 2006, P. 112, 2008/03

We investigated the gene expression of ${it C. elegans}$ following carbon and $$gamma$$ irradiation using DNA microarray analysis. We observed the 187 and 297 upregulated genes after $$gamma$$ and carbon irradiation with 100 Gy, respectively, in which 51 genes were upregulated following both irradiations. On the other hand, the 358 and 388 genes were downregulated after $$gamma$$ and carbon irradiation, respectively.

Journal Articles

Plutonium(VI) accumulation and reduction by lichen biomass; Correlation with U(VI)

Onuki, Toshihiko; Aoyagi, Hisao*; Kitatsuji, Yoshihiro; Samadfam, M.; Kimura, Yasuhiko; Purvis, O. W.*

Journal of Environmental Radioactivity, 77(3), p.339 - 353, 2004/08

 Times Cited Count:12 Percentile:28.71(Environmental Sciences)

no abstracts in English

Journal Articles

Irradiation behavior of rock-like oxide fuels

Yamashita, Toshiyuki; Kuramoto, Kenichi; Shirasu, Noriko; Nakano, Yoshihiro; Akie, Hiroshi; Nagashima, Hisao; Kimura, Yasuhiko; Omichi, Toshihiko*

Journal of Nuclear Materials, 320(1-2), p.126 - 132, 2003/07

 Times Cited Count:10 Percentile:58.26(Materials Science, Multidisciplinary)

Two irradiation tests on the rock-like oxide (ROX) fuels, small disk-shape fuel targets and pellet-type fuels, were performed in order to clarify in-pile irradiation stabilities. Swelling, fractional fission gas release (FGR) and phase change were examined by puncture test, profilometry and ceramography. YSZ single-phase fuel showed an excellent irradiation behavior, ie. low fission gas release (less than 3%), negligible swelling and no appreciable restructuring. The particle dispersed fuels showed lower swelling and higher fission gas release than those of mechanically blended fuels. Spinel decomposition and subsequence restructuring in the spinel matrix fuels was observed for the first time in the present investigation. It would be possible to reduce the FGR of the spinel matrix fuels, if the maximum fuels temperature is limited below 1700 K where neither spinel decomposition nor restructuring was observed. Damaged area of spinel matrix due to fission fragment irradiation seemed to be confined to thin layers around the surface of YSZ particles.

JAEA Reports

Post irradiation examination of (U,Pu)C and (U,Pu)N fuels for fast reactors; Destructive examination result of the fuel pins (Joint research)

Iwai, Takashi; Nakajima, Kunihisa; Kikuchi, Hironobu; Nagashima, Hisao; Kimura, Yasuhiko; Matsui, Hiroki; Arai, Yasuo

JAERI-Research 2002-038, 69 Pages, 2003/01

JAERI-Research-2002-038.pdf:12.46MB

Uranium-plutonium mixed carbide and nitiride fuel pins were fabricated in JAERI and irradiated at fast test rector JOYO based on the JAERI-JNC joint research program. The results of non-destructive and destructive post irradiation examinations cariied out at JNC were reported elsewhere. This report summarizes the results of destructive post irradiation examinations of (U,Pu)C and (U,Pu)N fuel pins carried out at JAERI.

JAEA Reports

Burn-up measurement of irradiated rock-like fuels

Shirasu, Noriko; Yamashita, Toshiyuki; Kanazawa, Hiroyuki; Kimura, Yasuhiko; Sudo, Kenji; Magara, Masaaki; Inagawa, Jun; Kono, Nobuaki; Nakahara, Yoshinori

JAERI-Research 2001-018, 23 Pages, 2001/03

JAERI-Research-2001-018.pdf:1.48MB

no abstracts in English

JAEA Reports

Post-irradiation examinations of uranium-plutonium mixed nitride fuel irradiated in JMTR; 89F-3A capsule

Iwai, Takashi; Nakajima, Kunihisa; Kikuchi, Hironobu; Kimura, Yasuhiko; Nagashima, Hisao; Sekita, Noriaki; Arai, Yasuo

JAERI-Research 2000-010, p.110 - 0, 2000/03

JAERI-Research-2000-010.pdf:20.61MB

no abstracts in English

JAEA Reports

Behavior of actinides and fission products in mixed nitride fuels irradiated in JMTR; 88F-5A capsule

Iwai, Takashi; Nakajima, Kunihisa; Kikuchi, Hironobu; Kimura, Yasuhiko; Kanaitsuka, Fumio; Sekita, Noriaki; Arai, Yasuo

JAERI-Research 2000-009, p.36 - 0, 2000/03

JAERI-Research-2000-009.pdf:6.16MB

no abstracts in English

Journal Articles

Role of lichen biomass on chemical speciation of Pu and U in ferrestrial environment

Onuki, Toshihiko; Samadfam, M.; Kimura, Yasuhiko; Kitatsuji, Yoshihiro; Aoyagi, Hisao; Purvis, O. W.*

Proceedings of the International Workshop on Distribution and Speciation of Radionuclides in the Environment, p.174 - 180, 2000/00

no abstracts in English

JAEA Reports

Behavior of plutonium and fission products in thermally stabilized mixed carbide fuel irradiated in JMTR

Iwai, Takashi; Arai, Yasuo; Nakajima, Kunihisa; Kimura, Yasuhiko; ;

JAERI-Research 96-066, 26 Pages, 1996/12

JAERI-Research-96-066.pdf:1.91MB

no abstracts in English

JAEA Reports

Behavior of plutonium and fission products in mixed uranium-plutonium carbide fuels irradiated in JMTR (84F-12A capsule)

Iwai, Takashi; Arai, Yasuo; Nakajima, Kunihisa; Kimura, Yasuhiko; ;

JAERI-Research 96-065, 47 Pages, 1996/12

JAERI-Research-96-065.pdf:4.1MB

no abstracts in English

JAEA Reports

Technical report: Technical development on silicide plate-type fuel experiment at Nuclear Safety Research Reactor

Yanagisawa, Kazuaki; Soyama, Kazuhiko; Ichikawa, Hiroki; ; Hoshino, Osamu; ; ; ; Kanazawa, Hiroyuki; Kimura, Yasuhiko; et al.

JAERI-M 91-114, 67 Pages, 1991/08

JAERI-M-91-114.pdf:4.28MB

no abstracts in English

JAEA Reports

Study on behavior of niobia dopant UO$$_{2}$$ fuel under reactivity initiated accident conditions

Yanagisawa, Kazuaki; Mimura, Hideaki; Kimura, Yasuhiko

JAERI-M 90-164, 64 Pages, 1990/09

JAERI-M-90-164.pdf:4.96MB

no abstracts in English

JAEA Reports

Confinement properties of pellet injected JT-60 plasmas

Kamada, Yutaka; Yoshino, Ryuji; ; Ozeki, Takahisa; Kawasaki, Kozo; Hiratsuka, Hajime; Miyo, Yasuhiko; Kimura, Haruyuki; Nishitani, Takeo; Yoshida, Hidetoshi; et al.

JAERI-M 89-050, 33 Pages, 1989/05

JAERI-M-89-050.pdf:1.05MB

no abstracts in English

Oral presentation

Re-assembly procedure of the irradiated fuel for the nuclear ship of Mutsu

Kaminaga, Norihisa; Nihei, Yasuo; Kimura, Yasuhiko; Kikuchi, Hiroyuki; Takahashi, Ishio; Matsuura, Takanobu; Suzuki, Kazuhiro; Kitamura, Toshikatsu; Sato, Yasuo; Hatanaka, Kazuo*

no journal, , 

no abstracts in English

Oral presentation

Non-destructive oxide thickness measurement for BWR fuel rod "Development of crud removal technique"

Sato, Atsushi; Shiina, Hidenori; Kataoka, Kentaro*; Otomo, Susumu*; Kakiuchi, Kazuo*; Ohira, Koichi*; Itagaki, Noboru*; Kaminaga, Norihisa; Kimura, Yasuhiko; Suzuki, Kazuhiro; et al.

no journal, , 

Oral presentation

Determination of hydrogen concentration in Zircaloy cladding using hot vacuum extraction method with two-step heating

Obata, Hiroki; Toyokawa, Takuya; Tomita, Takeshi; Kimura, Yasuhiko

no journal, , 

Hydrogen absorption to the fuel cladding is increase on the high burn-up fuel. The concentration of absorbed hydrogen causes the cladding embrittlement which might become the origination of fractures of the cladding. Therefore, it's important to measure the hydrogen volume in the cladding to estimate the safety margin of the irradiated cladding. In the previous method of hot vacuum extraction, the hydrogen is released and measured as the melting condition of the cladding. It cannot be evaluated the hydrogen volume only in the cladding metal phase. The hydrogen absorption in the cladding metal phase is strongly-correlated the cladding embrittlement. The two-step heating method has the benefit to measure the hydrogen in metal phase and oxide layer separately. The measuring method including the extraction temperature condition using unirradiated cladding will be reported.

28 (Records 1-20 displayed on this page)