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Journal Articles

Induction of genetic instability by transfer of a UV-A-irradiated chromosome

Urushibara, Ayumi*; Kodama, Seiji*; Yokoya, Akinari

Mutation Research; Genetic Toxicology And Environmental Mutagenesis, 766, p.29 - 34, 2014/05

 Times Cited Count:10 Percentile:37.18(Biotechnology & Applied Microbiology)

Journal Articles

Neutron powder diffraction study on the crystal and magnetic structures of BiCoO$$_3$$

Belik, A. A.*; Iikubo, Satoshi; Kodama, Katsuaki; Igawa, Naoki; Shamoto, Shinichi; Niitaka, Seiji*; Azuma, Masaki*; Shimakawa, Yuichi*; Takano, Mikio*; Izumi, Fujio*; et al.

Chemistry of Materials, 18(3), p.798 - 803, 2006/02

 Times Cited Count:272 Percentile:98.63(Chemistry, Physical)

The crystal and magnetic structures of polycrystalline BiCoO$$_3$$ have been determined by the Rietveldmethod from neutron diffraction data measured at temperatures from 5 to 520 K. BiCoO$$_3$$ (space groupP4mm; Z=1; a=3.72937(7) ${AA}$ and c=4.72382(15) ${AA}$ at room temperature; tetragonality c/a=1.267) is isotypic with BaTiO$$_3$$ and PbTiO$$_3$$ in the whole temperature range. BiCoO$$_3$$ is an insulator with a Neeltemperature of 470 K. A possible model for antiferromagnetic order is proposed with a propagationvector of k=(1/2, 1/2, 0). In this model, magnetic moments of Co$$^{3+}$$ ions are parallel to the c directionand align antiferromagnetically in the ab plane. The antiferromagnetic ab layers stack ferromagneticallyalong the c axis, forming a C-type antiferromagnetic structure. Refined magnetic moments at 5 and 300K are 3.24(2)$$mu$$$$_B$$ and 2.93(2)$$mu$$$$_B$$, respectively. The structure refinements revealed no deviation fromstoichiometry in BiCoO$$_3$$. BiCoO$$_3$$ decomposed in air above 720 K to give Co$$_3$$O$$_4$$ and sillenite-like Bi$$_{25}$$CoO$$_{39}$$.

Oral presentation

Analysis of genomic instability induced by the introduction of the UVA-irradiated chromosome

Urushibara, Ayumi; Kodama, Seiji*

no journal, , 

Ultraviolet (UV) radiation is one of the risk factors for skin cancer. However, UV, unlike ionizing radiation, is considered not to induce genomic instability. UV generates mainly base damage but not DNA double strand breaks (DSBs), the latter of which is thought to be strongly relevant to genomic instability. To find out whether genomic instability is induced by oxidative base damages, we transferred an UVA irradiated human chromosome 21 into unirradiated mouse cells using a microcell-mediated chromosome transfer method, and looked at the stability of the introduced human chromosome by Whole Chromosome Fluorescence in situ Hybridization (WCP-FISH). In cells that an UVA-irradiated chromosome was transferred, we found that the chromosome number changed remarkably (generating a polyploid), and that the aberration frequency was high for the unirradiated mouse chromosome as well as for the UV-irradiated chromosome. These results suggest that the UVA irradiated chromosomes induce genomic instability in unirradiated cells.

Oral presentation

Genomic instability induced by the non- double strand breaks

Urushibara, Ayumi; Kodama, Seiji*; Yokoya, Akinari

no journal, , 

no abstracts in English

Oral presentation

Oral presentation

Effect of UVA on the induction of the chromosomal instability

Urushibara, Ayumi; Kodama, Seiji*; Yokoya, Akinari

no journal, , 

no abstracts in English

Oral presentation

DNA damage caused by UV-A irradiation induces genetic instability

Urushibara, Ayumi; Kodama, Seiji*; Yokoya, Akinari

no journal, , 

Oral presentation

Induction of genetic instability by transfection of UV-A irradiated chromosomes

Urushibara, Ayumi; Kodama, Seiji*

no journal, , 

Oral presentation

Genetic instability induced by the transfer of UV-A irradiated chromosomes

Urushibara, Ayumi; Kodama, Seiji*; Yokoya, Akinari

no journal, , 

no abstracts in English

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