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Journal Articles

Measurements of electron-induced neutrons as a tool for determination of electron temperature of fast electrons in the task of optimization laser-produced plasma ions acceleration

Sakaki, Hironao; Nishiuchi, Mamiko; Maeda, Shota; Sagisaka, Akito; Pirozhkov, A. S.; Pikuz, T.; Faenov, A.*; Ogura, Koichi; Fukami, Tomoyo; Matsukawa, Kenya*; et al.

Review of Scientific Instruments, 85(2), p.02A705_1 - 02A705_4, 2014/02

 Times Cited Count:2 Percentile:13.22(Instruments & Instrumentation)

High intensity laser-plasma interaction has attracted considerable interest for a number of years. The laser-plasma interaction is accompanied by generation of various charged particle beams. Results of simultaneous novel measurements of electron-induced photonuclear neutrons (photoneutron), which are a diagnostic of the laser-plasma interaction, are proposed to use for optimization of the laser-plasma ion generation. The proposed method is demonstrated by the laser irradiation with the intensity os 1$$times$$10$$^{21}$$ W/cm$$^{2}$$ on the metal foil target. The photoneutrons are measured by using NE213 liquid scintillation detectors. Heavy-ion signal is registered with the CR39 track detector simultaneously. The measured signals of the electron-induced photoneutrons are well reproduced by using the Particle and Heavy Ion Transport code System (PHITS). The results obtained provide useful approach for analyzing the various laser based ion beams.

Journal Articles

Measurement of DNA double-strand break yield in human cancer cells by high-current, short-duration bunches of laser-accelerated protons

Yogo, Akifumi; Sato, Katsutoshi; Nishikino, Masaharu; Maeda, Takuya*; Sakaki, Hironao; Hori, Toshihiko*; Ogura, Koichi; Nishiuchi, Mamiko; Teshima, Teruki*; Nishimura, Hiroaki*; et al.

Japanese Journal of Applied Physics, 50(10), p.106401_1 - 106401_7, 2011/10

 Times Cited Count:8 Percentile:37.66(Physics, Applied)

Journal Articles

Development of laser-driven quasi-monoenergetic proton beam line for radiobiology

Yogo, Akifumi; Maeda, Takuya; Hori, Toshihiko; Sakaki, Hironao; Ogura, Koichi; Nishiuchi, Mamiko; Sagisaka, Akito; Bolton, P.; Murakami, Masao*; Kawanishi, Shunichi; et al.

Nuclear Instruments and Methods in Physics Research A, 653(1), p.189 - 192, 2011/10

 Times Cited Count:9 Percentile:62.21(Instruments & Instrumentation)

Journal Articles

Radiobiology with laser-accelerated quasi-monoenergetic proton beams

Yogo, Akifumi; Maeda, Takuya*; Hori, Toshihiko*; Sakaki, Hironao; Ogura, Koichi; Nishiuchi, Mamiko; Sagisaka, Akito; Bolton, P.; Murakami, Masao*; Kawanishi, Shunichi*; et al.

Proceedings of SPIE Europe Optics + Optoelectronics 2011, Vol.8079, 8 Pages, 2011/04

Journal Articles

Measurement of relative biological effectiveness of protons in human cancer cells using a laser-driven quasimonoenergetic proton beamline

Yogo, Akifumi; Maeda, Takuya; Hori, Toshihiko; Sakaki, Hironao; Ogura, Koichi; Nishiuchi, Mamiko; Sagisaka, Akito; Kiriyama, Hiromitsu; Okada, Hajime; Kanazawa, Shuhei; et al.

Applied Physics Letters, 98(5), p.053701_1 - 053701_3, 2011/02

 Times Cited Count:82 Percentile:94.07(Physics, Applied)

Journal Articles

Test beam-line for laser-driven proton therapy

Sakaki, Hironao; Nishiuchi, Mamiko; Hori, Toshihiko; Bolton, P.; Yogo, Akifumi; Ogura, Koichi; Sagisaka, Akito; Pirozhkov, A. S.; Orimo, Satoshi; Kondo, Kiminori; et al.

Proceedings of 7th Annual Meeting of Particle Accelerator Society of Japan (DVD-ROM), p.312 - 315, 2010/08

The beam transport test is carried out through the test beam line of the laser-driven proton accelerator which consists of the phase rotation cavity, PMQ, and bending magnet. The laser system used is J-KAREN at JAEA. The final transmitted bunch duration and transverse profile are well predicted by the PARMILA particle transport code by assuming relatively low initial current of the proton beam. The most probable explanation for this is the space charge neutralization by the laser-plasma-electrons.

Journal Articles

Measured and simulated transport of 1.9 MeV laser-accelerated proton bunches through an integrated test beam line at 1 Hz

Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Bolton, P.; Ogura, Koichi; Sagisaka, Akito; Yogo, Akifumi; Mori, Michiaki; Orimo, Satoshi; Pirozhkov, A. S.; et al.

Physical Review Special Topics; Accelerators and Beams, 13(7), p.071304_1 - 071304_7, 2010/07

 Times Cited Count:25 Percentile:81.88(Physics, Nuclear)

A laser-driven repetition-rated 1.9 MeV proton beam line composed of permanent quadrupole magnets (PMQs), a radio frequency (rf) phase rotation cavity, and a tunable monochromator is developed to evaluate and to test the simulation of laser-accelerated proton beam transport through an integrated system for the first time. In addition, the proton spectral modulation and focusing behavior of the rf phase rotationcavity device is monitored with input from a PMQ triplet. In the 1.9 MeV region we observe very weakproton defocusing by the phase rotation cavity. The final transmitted bunch duration and transverse profile are well predicted by the PARMILA particle transport code. The transmitted proton beam duration of 6 ns corresponds to an energy spread near 5% for which the transport efficiency is simulated to be 10%. The predictive capability of PARMILA suggests that it can be useful in the design of future higher energy transport beam lines as part of an integrated laser-driven ion accelerator system.

Journal Articles

Laser-driven proton accelerator for medical application

Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Bolton, P.; Ogura, Koichi; Sagisaka, Akito; Yogo, Akifumi; Mori, Michiaki; Orimo, Satoshi; Pirozhkov, A. S.; et al.

Proceedings of 1st International Particle Accelerator Conference (IPAC '10) (Internet), p.88 - 90, 2010/05

The concept of a compact ion particle accelerator has become attractive in view of recent progress in laser-driven ion acceleration. We report here the recent progress in the laser-driven proton beam transport at the Photo Medical Research Center (PMRC) at JAEA, which is established to address the challenge of laser-driven ion accelerator development for ion beam cancer therapy.

JAEA Reports

Evaluation of neutron fluence on JOYO core structure components

Ishida, Koichi; Maeda, Shigetaka; Saikawa, Takuya*; Masui, Tomohiko*

JNC TN9400 2002-005, 68 Pages, 2002/03

JNC-TN9400-2002-005.pdf:2.14MB

It is essential to evaluate the radiation damage of core structure materials used for core support plate and reactor vessel to maintain the safe operation of nuclear reactor plant. Therefore, surveillance tests for the irradiated specimen have been conducted in the experimental fast reactor JOYO to assure the integrity and to evaluate the life time. Neutron fluence and related spectral information are key palameters in evaluation of irradiation effects on the mechanical properties. They are usually predicted based on the calculation using the DORT two-dimensional transport code. In order to evaluate the calculation accuracy, the surveillance irradiation rigs (SVIRs) with dosimeter sets and gradient-monitor to monitor neutron fluences and temperatures were loaded several positions of the JOYO MK-II core. They were irradiated between 34$$^{th}$$ and 35$$^{th}$$ cycle. Based on the verification, the JOYO neutron field was precisely characterized and the calculated neutron flux at the positions of irradiated specimen and those of the core structure components need to be evaluated were corrected based on the experiments. As a result of this study, the following items are concluded: (1)The maximum fast neutron fluence (E$$>$$ 0.1Mev) on surveillance test specimen is determined as 2.07$$times$$10$$^{22}$$n/cm$$^{2}$$ at 9th row of the core. (2)The neutron fluences at the positions of surveillance test specimen were higher than those of the core structure components. (3)For the core support plate which seems to be most critical for JOYO life time, the fast neutron fluence at present is 9.38$$times$$10$$^{20}$$n/cm$$^{2}$$ and will reach 2.31$$times$$10$$^{21}$$ n/cm$$^{2}$$ at the end of life. The fast neutron fluence of reactor vessel is 3.12$$times$$10$$^{19}$$n/cm$$^{2}$$ at present and will reach 4.83$$times$$10$$^{19}$$n/cm$$^{2}$$ at the end of life.

JAEA Reports

Dosimetry technique to characterize neutron field of JOYO MK-II

Maeda, Shigetaka; Saikawa, Takuya*; Aoyama, Takafumi

JNC TN9410 2001-005, 219 Pages, 2001/03

JNC-TN9410-2001-005.pdf:4.92MB

Neutron fluence and related spectral information are key parameters in post-irradiation test analysis so they need to be evaluated accuracy. Nuclear calculations and a number of reactor dosimetry tests have been conducted in the JOYO experimental fast reactor to assure reliable and accurate neutron fluence for fuel and material irradiation tests. This paper describes the multiple activation foil dosimetry technique for neutron fluence evaluation. Neutron fluence was determined with neutron spectrum adjustment using measured reaction rates of a set of activation foils. Dosimetry results from individual fuel and material irradiation tests and a surveillance test characterized the neutron field of the JOYO MK-II core. Neutron flux in the JOYO core region was calculated using diffusion theory in a three-dimensional Hex-Z geometry. Flux in the stainless steel reflector region, which is outside the core, was calculated using the DORT two-dimensional transport calculation code. It is essential to correct the dosimetry results for locations far outside the core region. With corrected values, the calculated to experimental value (C/E) was approximately 1.05 in the core region and 1.1$$sim$$1.5 in the reflector region.

Oral presentation

Research study to advance irradiation field characterization method of Joyo MK-III core, 2; Evaluation of neutron irradiation condition by mean of neutron dosimetry

Maeda, Shigetaka; Ito, Chikara; Aoyama, Takafumi; Saikawa, Takuya*; Masui, Tomohiko*

no journal, , 

In 2003, Joyo MK-III core was upgraded to increase the irradiation testing capability. This paper describes the details of distributions of neutron flux and reaction rate in the MK-III core that was measured by characterization tests during the first two operating cycles. The calculation accuracy of the core management codes HESTIA, TORT and MCNP, was also evaluated by the measured data. The calculated fission rates of $$^{235}$$U by HESTIA agreed well with the measured one within approximately 4% in the fuel region. MCNP could simulate within 6% in the central non-fuel irradiation test subassembly and the radial reflector region, while large discrepancies were obtained in TORT results. Hence, the precise geometry model was effective in evaluating the neutron spectrum and the flux at such locations.

Oral presentation

Current status of the HIBMC, providing particle beam radiation therapy for more than 2,600 patients, and the prospects of laser-driven proton radiotherapy

Murakami, Masao*; Demizu, Yusuke*; Niwa, Yasue*; Nagayama, Shinichi*; Maeda, Takuya*; Baba, Masashi*; Miyawaki, Daisuke*; Terashima, Kazuki*; Arimura, Takeshi*; Mima, Masayuki*; et al.

no journal, , 

Oral presentation

Towards the laser-driven proton accelerator for cancer therapy; Benchmark test of the PARMILA code at the transport and irradiation test beam line

Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Bolton, P.; Ogura, Koichi; Yogo, Akifumi; Pirozhkov, A. S.; Sagisaka, Akito; Orimo, Satoshi; Mori, Michiaki; et al.

no journal, , 

no abstracts in English

Oral presentation

Radiobiological effects by the irradiation of laser-accelerated proton beams

Yogo, Akifumi; Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Sato, Katsutoshi; Nishikino, Masaharu; Maeda, Takuya; Mori, Michiaki; Ogura, Koichi; Orimo, Satoshi; et al.

no journal, , 

no abstracts in English

Oral presentation

Measurements of RBE for DNA double-strand break induction by laser-accelerated proton beams

Yogo, Akifumi; Sato, Katsutoshi; Nishikino, Masaharu; Maeda, Takuya; Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Mori, Michiaki; Ogura, Koichi; Orimo, Satoshi; et al.

no journal, , 

no abstracts in English

Oral presentation

Prototype of beam transport line for laser-driven proton therapy

Sakaki, Hironao; Nishiuchi, Mamiko; Hori, Toshihiko; Kondo, Kiminori; Ogura, Koichi; Yogo, Akifumi; Sagisaka, Akito; Orimo, Satoshi; Mori, Michiaki; Tampo, Motonobu; et al.

no journal, , 

We constructed prototype transportation system of the laser driven 2.0MeV by using nuclear power mechanism J-KAREN laser, and we measured and analyzed this beam line.

Oral presentation

The Integrated laser-driven ion accelerator system; Concept and requirements for laser-driven ion beam radiotherapy

Bolton, P.; Abe, Mitsuyuki*; Akagi, Takashi*; Nuesslin, F.*; Hori, Toshihiko; Iwashita, Yoshihisa*; Kawanishi, Shunichi; Kondo, Kiminori; Maeda, Takuya; Molls, M.*; et al.

no journal, , 

Oral presentation

Comparison of irradiation effects of synchrotron particle beam and laser driven particle beam irradiation in human cancer cell

Maeda, Takuya; Yogo, Akifumi; Demizu, Yusuke*; Hori, Toshihiko; Sakaki, Hironao; Tomoe, Yusuke*; Kondo, Kiminori; Murakami, Masao*

no journal, , 

Oral presentation

Radiobiology with laser-accelerated ion beams; Application of the quasi-monoenergetic proton beamline

Yogo, Akifumi; Maeda, Takuya*; Hori, Toshihiko*; Sakaki, Hironao; Ogura, Koichi; Nishiuchi, Mamiko; Sagisaka, Akito; Bolton, P.; Murakami, Masao*; Kondo, Kiminori

no journal, , 

Oral presentation

RBE of laser-accelerated protons for the inactivation of human cancer cells

Yogo, Akifumi; Hori, Toshihiko*; Sakaki, Hironao; Ogura, Koichi; Nishiuchi, Mamiko; Bolton, P.; Kondo, Kiminori; Maeda, Takuya*

no journal, , 

no abstracts in English

27 (Records 1-20 displayed on this page)