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Journal Articles

Temporal variability of $$^{137}$$Cs concentrations in coastal sediments off Fukushima

Suzuki, Shotaro*; Amano, Yosuke*; Enomoto, Masahiro*; Matsumoto, Akira*; Morioka, Yoshiaki*; Sakuma, Kazuyuki; Tsuruta, Tadahiko; Kaeriyama, Hideki*; Miura, Hikaru*; Tsumune, Daisuke*; et al.

Science of the Total Environment, 831, p.154670_1 - 154670_15, 2022/07

 Times Cited Count:2 Percentile:29.93(Environmental Sciences)

Journal Articles

Thermally altered subsurface material of asteroid (162173) Ryugu

Kitazato, Kohei*; Milliken, R. E.*; Iwata, Takahiro*; Abe, Masanao*; Otake, Makiko*; Matsuura, Shuji*; Takagi, Yasuhiko*; Nakamura, Tomoki*; Hiroi, Takahiro*; Matsuoka, Moe*; et al.

Nature Astronomy (Internet), 5(3), p.246 - 250, 2021/03

 Times Cited Count:43 Percentile:96.93(Astronomy & Astrophysics)

Here we report observations of Ryugu's subsurface material by the Near-Infrared Spectrometer (NIRS3) on the Hayabusa2 spacecraft. Reflectance spectra of excavated material exhibit a hydroxyl (OH) absorption feature that is slightly stronger and peak-shifted compared with that observed for the surface, indicating that space weathering and/or radiative heating have caused subtle spectral changes in the uppermost surface. However, the strength and shape of the OH feature still suggests that the subsurface material experienced heating above 300 $$^{circ}$$C, similar to the surface. In contrast, thermophysical modeling indicates that radiative heating does not increase the temperature above 200 $$^{circ}$$C at the estimated excavation depth of 1 m, even if the semimajor axis is reduced to 0.344 au. This supports the hypothesis that primary thermal alteration occurred due to radiogenic and/or impact heating on Ryugu's parent body.

Journal Articles

Small-sized human immunodeficiency virus type-1 protease inhibitors containing allophenylnorstatine to explore the S2' pocket

Hidaka, Koshi*; Kimura, Toru*; Abdel-Rahman, H. M.*; Nguyen, J.-T.*; McDaniel, K. F.*; Kohlbrenner, W. E.*; Molla, A.*; Adachi, Motoyasu; Tamada, Taro; Kuroki, Ryota; et al.

Journal of Medicinal Chemistry, 52(23), p.7604 - 7617, 2009/07

 Times Cited Count:19 Percentile:44.7(Chemistry, Medicinal)

A series of HIV protease inhibitor based on the allophenylnorstatine structure with various P2' moieties were synthesized. Among these analogues, we discovered that a small allyl group would maintain potent enzyme inhibitory activity compared to that of the $$o$$-methylbenzyl moiety in clinical candidate 1 (KNI-764, also known as JE-2147, AG-1776 or SM-319777). Introduction of an anilinic amino group to 2 (KNI-727) improved water-solubility and anti-HIV-1 activity. X-ray crystallographic analysis of 13k (KNI-1689) with a $$beta$$-methallyl group at P2' position revealed hydrophobic interactions with Ala28, Ile84, and Ile50' similar to that of 1. The presence of an additional methyl group on the allyl group in compound 13k significantly increased anti-HIV activity over 1, while providing a rational drug design for structural minimization and improving membrane permeability.

Journal Articles

Overview of the 3rd phase crossover research on migration of radionuclides in biosphere

Uchida, Shigeo*; Amano, Hikaru; Takahashi, Tomoyuki*; Chiba, Masaru*; Hisamatsu, Shunichi*; Enomoto, Shuichi*; Matsumoto, Shiro*

JAERI-Conf 2003-010, p.25 - 31, 2003/09

In the 3rd Stage Crossover Research (1998 to 2003), a project on Development of a dynamic transfer model of radionuclides in the soil ecosphere,is currently being promoted. The following five researches are carried out in this project. 1) Research into the forms of existence of nuclides and their change in the soil (NIRS and JAERI), 2) Research into the transition behavior of radionuclides in plants (IES, RIKEN and NIRS), 3) Research into the relation to the microorganism and on environmental remediation (RIKEN, JAERI and NIRS), 4) Research on the migration of radionuclides from atmosphere to soil and plant (MRI and JAERI), and 5) Database construction on transfer parameters (JAERI, NIRS and MRI). JAERI, MRI and NIRS are working on the development of a dynamic transfer model such as MOGRA for radionuclides on the basis of a gained knowledge about the environmental behavior through cooperation with universities, etc. This model is also capable of the predicting the behavior of materials that are harmful to the environment such as hazardous heavy metals discharged in the soil ecosphere. In this presentation, we will overview the ourcome of the 3rd stage research.

Journal Articles

Defect-induced phase separation in relaxor Pb(In$$_{1/2}$$Nb$$_{1/2}$$)O$$_3$$ crystals

Yoneda, Yasuhiro; Matsumoto, Norimasa; Terauchi, Hikaru*; Yasuda, Naohiko*

Journal of Physics; Condensed Matter, 15(3), p.467 - 474, 2003/01

 Times Cited Count:6 Percentile:35.62(Physics, Condensed Matter)

Thermal properties of ordered and disordered Pb(In$$_{1/2}$$Nb$$_{1/2}$$)O$$_3$$ (PIN) single clystals were investigated. The defect-induced phase separation provided a good agreement of the instability of the relaxor nd antiferroelectric states of the PIN crystals.

JAEA Reports

Proceedings of the Cross-over Symposium "New Approaches for Studies on Environmental Radioactivity"; November 26-27, 1998, RIKEN, Wako-shi, Japan

Matsumoto, Shiro*; Uchida, Shigeo*; Yamazawa, Hiromi; Amano, Hikaru

JAERI-Conf 99-001, 269 Pages, 1999/03

JAERI-Conf-99-001.pdf:15.56MB

no abstracts in English

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