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Lu-DOTATATE therapy in Japan宮司 典明*; 三輪 建太*; 佐藤 達彦; 他25名*
Radiological Physics and Technology, 19(1), p.165 - 175, 2026/03
This study evaluated inter-institutional variability in kidney dosimetry using common Lu-SPECT/CT datasets from the SNMMI Dosimetry Challenge. Ten Japanese centers calculated kidney volumes and absorbed doses with various organ- and voxel-based software. Manual VOI contouring caused large variability (CV up to 16.9%), reduced to 7.4% using common VOIs. Voxel-based dosimetry yielded higher doses but reduced variability, highlighting the need for algorithm standardization to ensure reliable Lu-DOTATATE kidney dosimetry in Japan.
Lu-DOTATATE peptide receptor radionuclide therapy三輪 建太*; 柿野 諒*; 佐藤 達彦; 古田 琢哉; 宮司 典明*; 山尾 天翔*; 山下 康輔*; 寺内 隆司*
Physical and Engineering Sciences in Medicine, 48(2), p.949 - 957, 2025/06
被引用回数：3 パーセンタイル：73.58(Engineering, Biomedical)RT-PHITSは、PHITSを放射線治療分野に応用するための統合パッケージで、患者のCT/SPECT画像をPHITSの入力形式に変換してその線量評価を行うことができる。本稿では、Lu-DOTATATEペプチド受容体核医学療法後のSPECT/CT画像とRT-PHITSを用いた個別線量測定の実現可能性について検討する。
