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Pt-labeled platinum complex and evaluation of its biodistribution in healthy miceOmokawa, Marina*; Kimura, Hiroyuki*; Hatsukawa, Yuichi*; Kawashima, Hidekazu*; Tsukada, Kazuaki; Yagi, Yusuke*; Naito, Yuki*; Yasui, Hiroyuki*
Bioorganic & Medicinal Chemistry, 97, p.117557_1 - 117557_6, 2024/01
Times Cited Count：0 Percentile：0.01(Biochemistry & Molecular Biology)Ohshima, Hiroyuki; Morishita, Masaki*; Aizawa, Kosuke; Ando, Masanori; Ashida, Takashi; Chikazawa, Yoshitaka; Doda, Norihiro; Enuma, Yasuhiro; Ezure, Toshiki; Fukano, Yoshitaka; et al.
Sodium-cooled Fast Reactors; JSME Series in Thermal and Nuclear Power Generation, Vol.3, 631 Pages, 2022/07
This book is a collection of the past experience of design, construction, and operation of two reactors, the latest knowledge and technology for SFR designs, and the future prospects of SFR development in Japan. It is intended to provide the perspective and the relevant knowledge to enable readers to become more familiar with SFR technology.
Suzuki, Hiroaki*; Morita, Yoshihiro*; Naito, Masanori*; Nemoto, Yoshiyuki; Kaji, Yoshiyuki
Mechanical Engineering Journal (Internet), 7(3), p.19-00450_1 - 19-00450_17, 2020/06
In this study, the SAMPSON code was modified to evaluate severe accidents in a spent fuel pool (SFP). Air oxidation models based on oxidation data obtained on the Zircaroy-4 cladding (ANL model) and the Zircaroy-2 cladding (JAEA model) were included in the modified SAMPSON code. Experiments done by Sandia National Laboratory using simulated fuel assemblies equivalent to those of an actual BWR plant were analyzed by the modified SAMPSON code to confirm the functions for analysis of the severe SFP accidents. The rapid fuel rod temperature rise due to the Zr air oxidation reaction could be reasonably evaluated by the SAMPSON analysis. The SFP accident analyses were conducted with different initial water levels which were no water, water level at bottom of active fuel, and water level at half of active fuel. The present analysis showed that the earliest temperature rise of the fuel rod surface occurred when there was no water in the SFP and natural circulation of air became possible.
Suzuki, Ryohei*; Tani, Yukinori*; Naito, Hirotaka*; Miyata, Naoyuki*; Tanaka, Kazuya
Catalysts, 10(1), p.44_1 - 44_15, 2020/01
Times Cited Count：10 Percentile：40.35(Chemistry, Physical)We prepared biogenic Mn oxides (BMOs) using 
strain KR21-2, and subsequently conducted single or repeated treatment experiments in Cr(NO
) at pH6.0. Under aerobic conditions, newly formed BMOs exhibited a rapid production of Cr(VI) without a significant release of Mn(II), demonstrating that newly formed BMO mediates a catalytic oxidation of Cr(III) with a self-regeneration step of reduced Mn. In anaerobic solution, newly formed BMOs showed a cessation of Cr(III) oxidation in the early stage of the reaction, and subsequently had a much smaller Cr(VI) production with significant release of reduced Mn(II).
Katsuta, Nagayoshi*; Takano, Masao*; Sano, Naomi; Tani, Yukinori*; Ochiai, Shinya*; Naito, Sayuri*; Murakami, Takuma*; Niwa, Masakazu; Kawakami, Shinichi*
Sedimentology, 66(6), p.2490 - 2510, 2019/10
Times Cited Count：7 Percentile：49.6(Geology)Micro-X-ray fluorescence (XRF) scanning spectroscopy of marine and lake sedimentary sequences can provide detailed paleoenvironmental records available through element intensities proxy data. However, problems for effects of interstitial pore water on the micro-XRF intensities have been pointed out so far because of direct measurement on the split wet sediment surfaces. In this study, new methods for the XRF corrections were developed by being considered with the micro-X-ray scanning spectroscopy.
Morita, Yoshihiro*; Suzuki, Hiroaki*; Naito, Masanori*; Nemoto, Yoshiyuki; Kaji, Yoshiyuki
Proceedings of 27th International Conference on Nuclear Engineering (ICONE-27) (Internet), 9 Pages, 2019/05
In this study, the SAMPSON code was modified to evaluate severe accidents in a spent fuel pool (SFP). Not only the SFP but also upper spaces of the SFP, walls of the reactor building, and the blowout panel were included. Air oxidation models obtained by the Zircaroy-4 cladding (ANL model) and the Zircaroy-2 cladding (JAEA model) were included in the modified SAMPSON code. Experiments done by Sandia National Laboratory using simulated fuel assemblies equivalent to those of an actual BWR plant were analyzed by the modified SAMPSON code to confirm the functions for analysis of the severe SFP accidents.
Suzuki, Hiroaki*; Morita, Yoshihiro*; Naito, Masanori*; Nemoto, Yoshiyuki; Nagatake, Taku; Kaji, Yoshiyuki
Proceedings of 27th International Conference on Nuclear Engineering (ICONE-27) (Internet), 7 Pages, 2019/05
In this paper, modification of the SAMPSON code was carried out to enable the analysis of spray cooling. The SAMPSON analysis of a spray cooling experiment was performed to confirm reproducibility of spray cooling behavior of fuel claddings. The modified SAMPSON code was applied to a hypothetical loss-of-coolant accident analysis of the SFP. Effectiveness of spray cooling on cladding temperature behavior was investigated. The SAMPSON analysis showed that spraying from the top of the SFP was effective for cooling the fuel assemblies exposed to the gas phase.
Ito, Chikara; Naito, Hiroyuki; Ishikawa, Takashi; Ito, Keisuke; Wakaida, Ikuo
JPS Conference Proceedings (Internet), 24, p.011038_1 - 011038_6, 2019/01
A high-radiation resistant optical fiber has been developed in order to investigate the interiors of the reactor pressure vessels and the primary containment vessels at the Fukushima Daiichi Nuclear Power Station. The tentative dose rate in the reactor pressure vessels is assumed to be up to 1 kGy/h. We developed a radiation resistant optical fiber consisting of a 1000 ppm hydroxyl doped pure silica core and 4 % fluorine doped pure silica cladding. We attempted to apply the optical fiber to remote imaging technique by means of fiberscope. The number of core image fibers was increased from 2000 to 22000 for practical use. The transmissive rate of infrared images was not affected after irradiation of 1 MGy. No change in the spatial resolution of the view scope by means of image fiber was noted between pre- and post-irradiation. We confirmed the applicability of the probing system, which consists of a view scope using radiation-resistant optical fibers.
Tamura, Jun; Kondo, Yasuhiro; Morishita, Takatoshi; Ao, Hiroyuki*; Naito, Fujio*; Otani, Masashi*; Nemoto, Yasuo*
Journal of Physics; Conference Series, 1067(5), p.052009_1 - 052009_6, 2018/09
Times Cited Count：0 Percentile：0.11(Physics, Particles & Fields)In the Japan Proton Accelerator Research Complex (J-PARC) linac, the Annular-ring Coupled Structure (ACS) cavities have been stably operating. To maintain this operation availability, we manufactured three pillbox-type RF windows for the ACS cavities in fiscal year 2015 and 2017. It is desirable to minimize the RF reflection of the RF window to prevent standing waves from exciting between the cavity and the RF window, and not to significantly change the optimized coupling factor between the cavity and the waveguide. To realize the minimization, the relative permittivities of the ceramic disks of the RF windows were evaluated by measuring the resonant frequencies of the pillbox cavity containing the ceramic disk. On the basis of the evaluated relative permittivities, the pillbox-part lengths of the RF windows were determined. The measured Voltage Standing Wave Ratios (VSWRs) of the manufactured RF windows are just about 1.08 and these are applicable for the practical use.
McKinley, I. G.*; Masuda, Sumio*; Hardie, S. M. L.*; Umeki, Hiroyuki*; Naito, Morimasa; Takase, Hiroyasu*
Journal of Energy, 2018, p.7546158_1 - 7546158_8, 2018/07
The Japanese geological disposal programme for radioactive waste is based on a volunteering approach to siting, which places particular emphasis on the need for public acceptance. This emphasises the development of a repository project as a partnership with local communities and involves stakeholders in important decisions associated with key milestones in the selection of repository sites and subsequent construction, operation and closure. To date, however, repository concept development has proceeded in a more traditional manner, focusing particularly on ease of developing a post-closure safety case. In the current project, we have attempted to go further by assessing what requirements stakeholders would place on a repository and assessing how these could be used to re-think repository designs so that they meet the desires of the public without compromising critical operational or long-term safety.
Katsuta, Nagayoshi*; Ikeda, Hisashi*; Shibata, Kenji*; Kokubu, Yoko; Murakami, Takuma*; Tani, Yukinori*; Takano, Masao*; Nakamura, Toshio*; Tanaka, Atsushi*; Naito, Sayuri*; et al.
Global and Planetary Change, 164, p.11 - 26, 2018/05
Times Cited Count：10 Percentile：43.77(Geography, Physical)Paleoenvironmental and paleoclimate changes in Siberia were reconstructed by continuous, high-resolution records of chemical compositions from a sediment core retrieved from the Buguldeika Saddle, Lake Baikal, dating back to the last 33 cal. ka BP. The Holocene climate followed by a shift at ca. 6.5 cal. ka BP toward warm and dry, suggesting that the climate system transition from the glacial to interglacial state occurred. In the last glacial period, the deposition of carbonate mud from the Primorsky Range was associated with Heinrich events (H3 and H1) and the Selenga River inflow was caused by meltwater of mountain glaciers in the Khamar-Daban Range. The anoxic bottom-water during Allerod-Younger Dryas was probably a result of weakened ventilation associated with reduced Selenga River inflow and microbial decomposition of organic matters from the Primorsky Range. The rapid decline in precipitation during the early Holocene may have been a response to the 8.2 ka cooling event.
Shibata, Takanori*; Asano, Hiroyuki; Ikegami, Kiyoshi*; Naito, Fujio*; Nammo, Kesao*; Oguri, Hidetomo; Okoshi, Kiyonori; Shinto, Katsuhiro; Takagi, Akira*; Ueno, Akira
AIP Conference Proceedings 1869, p.030017_1 - 030017_11, 2017/08
Times Cited Count：4 Percentile：85.09(Physics, Applied)From September 2014, operation of Cs-seeded, multi-cusp, Radio Frequency (RF), hydrogen negative ion source (J-PARC source) has been started. The operation for 1,000 hours of J-PARC source has been achieved with H
beam current 45 mA and duty factor of 1.25 % (0.5 msec and 25 Hz). In the present study, mechanisms of hydrogen plasma ramp-up and H production/transport processes in the steady state (which lasts for few 100 us) are investigated by numerical modeling for RF plasma. In the simulation, charged particle (e, H
, H
, and Cs) transport, time variations of inductive and capacitive electromagnetic field, collision processes between charged and neutral (H, H
) particles are solved simultaneously. The model is applied to KEK parallel computation System-A with 32 nodes and 256 GB memory in order to solve high density RF plasma up to around 10
m
with adequate statisticity. In the presentation, time variations of plasma density distributions and average energy are shown with electromagnetic field variations.
Shibata, Takanori*; Ikegami, Kiyoshi*; Liu, Y.*; Maruta, Tomofumi*; Naito, Fujio*; Takagi, Akira*; Asano, Hiroyuki; Kondo, Yasuhiro; Miura, Akihiko; Oguri, Hidetomo; et al.
Proceedings of 28th International Linear Accelerator Conference (LINAC 2016) (Internet), p.251 - 253, 2017/05
After upgrade of J-PARC Linac in 2014, Low Energy Beam Transport (LEBT) beam commissioning of the J-PARC LINAC has been made for improving H beam intensity extracted from Linac. Currents of two solenoid coils and steering magnets in LEBT are optimized with extraction and acceleration voltages for static acceleration in ion source (IS) which decides on an initial emittance diagram of H beam. As a result of LEBT and IS parameter optimization, beam transmission rate of RFQ has been reached up to 96% in 50 mA H current operation. Moreover, PIC-MC (Particle-In-Cell Monte-Carlo) simulation models developed for H transport in LEBT. Comparison between experimental and numerical results are presented to clarify beam physics from IS exit to RFQ entrance.
Otani, Masashi*; Kawamura, Naritoshi*; Mibe, Tsutomu*; Naito, Fujio*; Yoshida, Mitsuhiro*; Hasegawa, Kazuo; Ito, Takashi; Kondo, Yasuhiro; Hayashizaki, Noriyosu*; Iwashita, Yoshihisa*; et al.
Proceedings of 28th International Linear Accelerator Conference (LINAC 2016) (Internet), p.1037 - 1041, 2017/05
We are developing a linac dedicated to the muon acceleration. It enables us to measure the muon anomalous magnetic moment with an accuracy of 0.1 ppm and search for electric dipole moment with a sensitivity of 10
cm to explore beyond Standard Model of elementary particle physics. As a first step for demonstration of the muon acceleration, we are developing the source of slow muon with which RFQ acceleration is conducted. This paper describes status of these developments.
Deguchi, Akira*; Umeki, Hiroyuki*; Ueda, Hiroyoshi*; Miyamoto, Yoichi; Shibata, Masahiro; Naito, Morimasa; Tanaka, Toshihiko*
LBNL-1006984 (Internet), p.12_1 - 12_22, 2016/12
The H12 report demonstrated the feasibility of safe and technically reliable geological disposal in 1999. The Government of Japan re-evaluated the geological disposal program in terms of technical feasibility based on state-of-the-art geosciences and implementation process, because more than 10 years have passed from H12 and the Great Earthquake and nuclear accident have increased public concern regarding nuclear issues and natural hazards to cause accidents at nuclear facilities. Following the re-evaluation, the Government concluded further to promote geological disposal program, and thus the Basic Policy for Final Disposal was revised in 2015 including a new approach to siting process with identification of "Scientifically Preferable Areas". NUMO and relevant research organizations such as JAEA have been carrying out R and D activities to increase technical reliability for geological disposal. NUMO has started to develop a generic safety case.
Kondo, Yasuhiro; Hasegawa, Kazuo; Ito, Takashi; Artikova, S.; Otani, Masashi*; Mibe, Tsutomu*; Naito, Fujio*; Yoshida, Mitsuhiro*; Kitamura, Ryo*; Iwashita, Yoshihisa*; et al.
Proceedings of 13th Annual Meeting of Particle Accelerator Society of Japan (Internet), p.66 - 69, 2016/11
We are developing a muon linac for the measurement of the muon anomalous magnetic moment and search for the muon electric dipole moment to explore beyond the Standard Model of elementary particle physics. This muon linac accelerate from room temperature to 212 MeV with normalized transverse emittances of about 1.5 
mm mrad. The muon linac consists of an ultra-slow muon source, a radio frequency quadrupole (RFQ) linac, an inter-digital H-mode drift tube linac (IH-DTL), a disk and washer coupled cavity linac (DAW CCL), and disk loaded structure (DLS) traveling-wave linac. In this paper, the status of the muon linac development, especially, the beam dynamics simulation is descried.
Naito, Fujio*; Anami, Shozo*; Ikegami, Kiyoshi*; Uota, Masahiko*; Ouchi, Toshikatsu*; Onishi, Takahiro*; Oba, Toshiyuki*; Obina, Takashi*; Kawamura, Masato*; Kumada, Hiroaki*; et al.
Proceedings of 13th Annual Meeting of Particle Accelerator Society of Japan (Internet), p.1244 - 1246, 2016/11
The proton linac installed in the Ibaraki Neutron Medical Research Center is used for production of the intense neutron flux for the Boron Neutron Capture Therapy (BNCT). The linac consists of the 3-MeV RFQ and the 8-MeV DTL. Design average beam current is 10mA. Target is made of Beryllium. First neutron production from the Beryllium target was observed at the end of 2015 with the low intensity beam as a demonstration. After the observation of neutron production, a lot of improvement s was carried out in order to increase the proton beam intensity for the real beam commissioning. The beam commissioning has been started on May 2016. The status of the commissioning is summarized in this report.
Otani, Masashi*; Naito, Fujio*; Mibe, Tsutomu*; Yoshida, Mitsuhiro*; Hasegawa, Kazuo; Ito, Takashi; Kondo, Yasuhiro; Hayashizaki, Noriyosu*; Iwashita, Yoshihisa*; Iwata, Yoshiyuki*; et al.
Proceedings of 7th International Particle Accelerator Conference (IPAC '16) (Internet), p.1543 - 1546, 2016/06
We are developing a linac dedicated to the muon acceleration. It enables us to measure the muon anomalous magnetic moment with an accuracy of 0.1 ppm and search for electric dipole moment with a sensitivity of 10-21e cm to explore beyond Standard Model of elementary particle physics. As a first step for demonstration of the muon acceleration, we are developing the source of slow muon with which RFQ acceleration is conducted. This paper described status of these developments.
Ishizawa, Akihiro*; Idomura, Yasuhiro; Imadera, Kenji*; Kasuya, Naohiro*; Kanno, Ryutaro*; Satake, Shinsuke*; Tatsuno, Tomoya*; Nakata, Motoki*; Nunami, Masanori*; Maeyama, Shinya*; et al.
Purazuma, Kaku Yugo Gakkai-Shi, 92(3), p.157 - 210, 2016/03
The high-performance computer system Helios which is located at The Computational Simulation Centre (CSC) in The International Fusion Energy Research Centre (IFERC) started its operation in January 2012 under the Broader Approach (BA) agreement between Japan and the EU. The Helios system has been used for magnetised fusion related simulation studies in the EU and Japan and has kept high average usage rate. As a result, the Helios system has contributed to many research products in a wide range of research areas from core plasma physics to reactor material and reactor engineering. This project review gives a short catalogue of domestic simulation research projects. First, we outline the IFERC-CSC project. After that, shown are objectives of the research projects, numerical schemes used in simulation codes, obtained results and necessary computations in future.
Shibata, Takanori*; Nishida, Kenjiro*; Mochizuki, Shintaro*; Mattei, S.*; Lettry, J.*; Hatayama, Akiyoshi*; Ueno, Akira; Oguri, Hidetomo; Okoshi, Kiyonori; Ikegami, Kiyoshi*; et al.
Review of Scientific Instruments, 87(2), p.02B128_1 - 02B128_3, 2016/02
Times Cited Count：3 Percentile：16.49(Instruments & Instrumentation)A numerical model of plasma transport and electromagnetic field in the J-PARC RF ion source has been developed to understand relation between antenna coil heat loadings and plasma production/transport processes. From the calculation, the local plasma density increase is observed in the region close to the antenna coil. The magnetic field line with absolute magnetic flux density 30-120 Gauss results in the magnetization of electron which leads to high local ionization rate. The results suggest that modification of magnetic configuration can be made to reduce plasma heat flux onto the antenna.
