Mechanisms of action of radon therapy on cytokine levels in normal mice and rheumatoid arthritis mouse model

Kataoka, Takahiro*; Naoe, Shota*; Murakami, Kaito*; Yukimine, Ryohei*; Fujimoto, Yuki*; Kanzaki, Norie; Sakoda, Akihiro; Mitsunobu, Fumihiro*; Yamaoka, Kiyonori*

Journal of Clinical Biochemistry and Nutrition, 70(2), p.154 - 159, 2022/03

https://doi.org/10.3164/jcbn.21-91

Evaluation of the redox state in mouse organs following radon inhalation

Kataoka, Takahiro*; Kanzaki, Norie; Sakoda, Akihiro; Shuto, Hina*; Yano, Junki*; Naoe, Shota*; Tanaka, Hiroshi; Hanamoto, Katsumi*; Terato, Hiroaki*; Mitsunobu, Fumihiro*; et al.

Journal of Radiation Research (Internet), 62(2), p.206 - 216, 2021/03

AA2020-0273.pdf:1.2MB

https://doi.org/10.1093/jrr/rraa129

Radon inhalation activates antioxidative functions in mouse organs, thereby contributing to inhibition of oxidative stress-induced damage. Therefore, in this study, we evaluated the redox state of various organs in mice following radon inhalation. Mice inhaled radon at concentrations of 2 or 20 kBq/m for 1, 3, or 10 days. The relationship between antioxidative function and oxidative stress was evaluated by principal component analysis (PCA) and correlation coefficient compared with control mice subjected to sham inhalation. These findings suggested that radon inhalation altered the redox state in organs, but that the characteristics varied depending on the redox state in organs.

Concentration dependence of suppression of DNA oxidative damage in mouse organs by radon inhalation

Masukawa, Yuki*; Kataoka, Takahiro*; Shuto, Hina*; Naoe, Shota*; Yano, Junki*; Kanzaki, Norie; Sakoda, Akihiro; Tanaka, Hiroshi; Hanamoto, Katsumi*; Mitsunobu, Fumihiro*; et al.

no journal, , 

no abstracts in English

Study on change characteristics of cytokines in mouse serum by radon inhalation

Naoe, Shota*; Kataoka, Takahiro*; Yano, Junki*; Shuto, Hina*; Kanzaki, Norie; Sakoda, Akihiro; Yamaoka, Kiyonori*

no journal, , 

no abstracts in English