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Takemoto, Noriyuki; Tsuchiya, Kunihiko; Nagao, Yoshiharu; Kitagishi, Shigeru; Naka, Michihiro; Kimura, Akihiro; Sano, Tadafumi*; Unesaki, Hironobu*; Yoshimoto, Takaaki*; Nakajima, Ken*; et al.
KURRI Progress Report 2010, P. 204, 2011/10
no abstracts in English
Tsuchiya, Kunihiko; Kitagishi, Shigeru; Nagao, Yoshiharu; Takemoto, Noriyuki; Naka, Michihiro; Kimura, Akihiro; Sano, Tadafumi*; Unesaki, Hironobu*; Yoshimoto, Takaaki*; Nakajima, Ken*; et al.
KURRI Progress Report 2009, P. 196, 2010/10
no abstracts in English
Tanaka, Naritake*; Kimura, Hitoshi*; Faried, A.*; Sakai, Makoto*; Sano, Takaaki*; Inose, Takanori*; Soda, Makoto*; Okada, Koji*; Nakajima, Masanobu*; Miyazaki, Tatsuya*; et al.
Cancer Science, 101(6), p.1487 - 1492, 2010/06
Times Cited Count:12 Percentile:32.57(Oncology)We examined the intracellular localization of cisplatin, a key chemotherapeutic agent, in esophageal cancer cell lines and determined their sensitivity to cisplatin using in-air micro-PIXE. Two human esophageal squamous cell carcinoma (ESCC) cell lines, TE-2 and TE-13, were examined for their response to cisplatin using MTT assay, flow cytometry and DNA fragmentation assays. Real-time reverse transcription-polymerase chain reaction was also used to evaluate the mRNA expression of multidrug resistance protein 2 (MRP2) in both cell lines. Platinum localizations of intracellular and intranuclear were measured using in-air micro-PIXE. TE-2 cells were more sensitive to cisplatin than TE-13 cells. The results of this study suggest that in-air micro-PIXE could be a useful quantitative method for evaluating the cisplatin sensitivity of individual cells. Finally, we speculate that MRP2 in the cell membrane may play an important role in regulating cisplatin sensitivity of ESCC cells.
Koizumi, Norikiyo; Takahashi, Yoshikazu; Nakajima, Hideo; Tsuchiya, Yoshinori; Matsui, Kunihiro; Nunoya, Yoshihiko; Ando, Toshinari; Hiyama, Tadao; Kato, Takashi; Isono, Takaaki; et al.
Teion Kogaku, 36(8), p.478 - 485, 2001/08
no abstracts in English
Koizumi, Norikiyo; Ando, Toshinari; Takahashi, Yoshikazu; Matsui, Kunihiro; Nakajima, Hideo; Tsuchiya, Yoshinori; Kikuchi, Kenji; Nunoya, Yoshihiko; Kato, Takashi; Isono, Takaaki; et al.
Senshin A15-gata Kagobutsu Chodendo Senzai Shimpojiumu Rombunshu, p.5 - 9, 2000/00
no abstracts in English
Shimizu, Yasuo*; Dobashi, Kunio*; Kusakabe, Takahiko*; Nagamine, Takeaki*; Oikawa, Masakazu*; Sato, Takahiro; Haga, Junji*; Okubo, Takeru; Ishii, Yasuyuki; Kamiya, Tomihiro; et al.
no journal, ,
no abstracts in English
Uchida, Mao*; Hirakawa, Moe*; Inoue, Keisuke*; Sano, Aaru*; Sakai, Takaaki*; Ezure, Toshiki; Tanaka, Masaaki
no journal, ,
Visualization measurements using a high-speed camera and numerical analyses were carried out for gas entrainment phenomenon due to free surface drifting vortices in an open rectangular channel. The applicability of gas core length based on numerical analyses was confirmed for drifting vortices in the open channel through the comparison with experimental results.