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Schaar, K.*; Spiegl, T.*; Sato, Tatsuhiko; Langematz, U.*
Journal of Environmental Radioactivity, 282, p.107592_1 - 107592_14, 2025/02
Times Cited Count：0 Percentile：0.00(Environmental Sciences)Parisi, A.*; Furutani, K. M.*; Sato, Tatsuhiko; Beltran, C. J.*
Medical Physics, 51(10), p.7589 - 7605, 2024/10
Times Cited Count：1 Percentile：0.00(Radiology, Nuclear Medicine & Medical Imaging)In this study, we have developed an approximate MKM (microdosimetric kinetic model) based on LET (dose-averaged linear energy transfer) to address the challenges of biological relative effectiveness (RBE) models for proton therapy. This is an attempt to apply the mechanism-based approach used in carbon ion therapy to proton beams. This LET-based MKM establishes a correlation between dose-averaged LET and microbiological indices and successfully models survival rates for multiple cell lines. This has resulted in a mathematical description of RBE based on physical quantities that can be readily used in proton therapy planning systems.
H to 
UParisi, A.*; Furutani, K. M.*; Sato, Tatsuhiko; Beltran, C. J.*
Quantum Beam Science (Internet), 8(3), p.18_1 - 18_16, 2024/09
Be for the detectability of solar proton eventsSchaar, K.*; Spiegl, T.*; Langematz, U.*; Sato, Tatsuhiko; Mekhaldi, F.*; Kunze, M.*; Miyake, Fusa*; Yoden, Shigeo*
Journal of Geophysical Research; Atmospheres, 129(11), p.e2023JD040463_1 - e2023JD040463_28, 2024/06
Times Cited Count：1 Percentile：53.84(Meteorology & Atmospheric Sciences)Mizuno, Rurie*; Niikura, Megumi*; Saito, Takeshi*; Matsuzaki, Teiichiro*; Sakurai, Hiroyoshi*; Amato, A.*; Asari, Shunsuke*; Biswas, S.*; Chiu, I.-H.; Gianluca, J.*; et al.
Nuclear Instruments and Methods in Physics Research A, 1060, p.169029_1 - 169029_14, 2024/03
Times Cited Count：1 Percentile：30.87(Instruments & Instrumentation)Watabe, Hiroshi*; Sato, Tatsuhiko; Yu, K. N.*; Zivkovic, M.*; Krstic, D.*; Nikezic, D.*; Kim, K. M.*; Yamaya, Taiga*; Kawachi, Naoki*; Tanaka, Hiroki*; et al.
Radiation Protection Dosimetry, 200(2), p.130 - 142, 2024/02
Times Cited Count：1 Percentile：30.19(Environmental Sciences)Previously, we have developed DynamicMC for modelling relative movement of ORNL phantom in a radiation field for MCNP. Using this software, 3-dimensional dose distributions in a phantom irradiated by a certain mono-energetic source can be deduced through its graphical user interface (GUI). In this study, we extended DynamicMC to be used in combination with the PHITS by providing it with a higher flexibility for dynamic movement for a less sophisticated anthropomorphic phantom. We anticipate that the present work and the developed open-source tools will be in the interest of nuclear radiation physics community for research and teaching purposes.
beam at J-PARC RCSSaha, P. K.; Harada, Hiroyuki; Yoneda, Hitoki*; Michine, Yurina*; Sato, Atsushi*; Shibata, Takanori*; Kinsho, Michikazu
Proceedings of 20th Annual Meeting of Particle Accelerator Society of Japan (Internet), p.59 - 63, 2023/11
Domal, S. J.*; Correa-Alfonso, C. M.*; Paulbeck, C. J.*; Griffin, K. T.*; Sato, Tatsuhiko; Funamoto, Sachiyo*; Cullings, H. M.*; Egbert, S. D.*; Endo, Akira; Hertel, N. E.*; et al.
Health Physics, 125(4), p.245 - 259, 2023/10
Times Cited Count：0 Percentile：0.00(Environmental Sciences)The RERF Working Group on Organ Dose (WGOD) has established the J45 (Japan 1945) series of high-resolution voxel phantoms, which were derived from the UF/NCI series of hybrid phantoms and scaled to match mid-1940s Japanese body morphometries. In this present study, we present the J45 pregnant female phantoms in both a kneeling and lying posture, and assess the dosimetric impact of these more anatomically realistic survivor models in comparisons to current organ doses given by the DS02 system. For the kneeling phantoms facing the bomb hypocenter, organ doses from bomb source photon spectra were shown to be overestimated by the DS02 system by up to a factor of 1.45 for certain fetal organs and up to a factor of 1.17 for maternal organs. For lying phantoms with their feet in the direction of the hypocenter, fetal organ doses from bomb source photon spectra were underestimated by the DS02 system by factors as low as 0.77 while maternal organ doses were overestimated by up to a factor of 1.38. Results from this study highlight the degree to which the existing DS02 system can differ from organ dosimetry based upon 3D radiation transport simulations using more anatomically realistic models of those survivors exposed during pregnancy while in a kneeling or lying position.
beam at J-PARCSaha, P. K.; Harada, Hiroyuki; Yoneda, Hitoki*; Michine, Yurina*; Sato, Atsushi*; Shibata, Takanori*; Kinsho, Michikazu; Johnson, D. E.*
Proceedings of 14th International Particle Accelerator Conference (IPAC 23) (Internet), p.2335 - 2338, 2023/09
OKondo, Yosuke*; Achouri, N. L.*; Al Falou, H.*; Atar, L.*; Aumann, T.*; Baba, Hidetada*; Boretzky, K.*; Caesar, C.*; Calvet, D.*; Chae, H.*; et al.
Nature, 620(7976), p.965 - 970, 2023/08
Times Cited Count：23 Percentile：94.90(Multidisciplinary Sciences)no abstracts in English
Ne at the transition into the island of inversion; Detailed structure study of NeWang, H.*; Yasuda, Masahiro*; Kondo, Yosuke*; Nakamura, Takashi*; Tostevin, J. A.*; Ogata, Kazuyuki*; Otsuka, Takaharu*; Poves, A.*; Shimizu, Noritaka*; Yoshida, Kazuki; et al.
Physics Letters B, 843, p.138038_1 - 138038_9, 2023/08
Times Cited Count：3 Percentile：64.77(Astronomy & Astrophysics)Detailed 
-ray spectroscopy of the exotic neon isotope Ne has been performed using the one-neutron removal reaction from Ne. Based on an analysis of parallel momentum distributions, a level scheme with spin-parity assignments has been constructed for Ne and the negative-parity states are identified for the first time. The measured partial cross sections and momentum distributions reveal a significant intruder p-wave strength providing evidence of the breakdown of the N = 20 and N = 28 shell gaps. Only a weak, possible f-wave strength was observed to bound final states. Large-scale shell-model calculations with different effective interactions do not reproduce the large p-wave and small f-wave strength observed experimentally, indicating an ongoing challenge for a complete theoretical description of the transition into the island of inversion along the Ne isotopic chain.
Paulbeck, C. J.*; Sato, Tatsuhiko; Funamoto, Sachiyo*; Lee, C.*; Griffin, K. T.*; Cullings, H. M.*; Egbert, S. D.*; Endo, Akira; Hertel, N. E.*; Bolch, W. E.*
Radiation and Environmental Biophysics, 62(3), p.317 - 329, 2023/08
Times Cited Count：2 Percentile：43.60(Biology)In our prior study [Radiat Res 192, 538-561 (2019)], we presented a new J45 (Japanese 1945) series of high-resolution phantoms of the adult pregnant female at 8-week, 15-week, 25-week, and 38-week post-conception. In this present study, we extend this work using realistic angular fluences from the DS02 system for up to nine different radiation categories and five shielding conditions. General findings are that the current DS02 fetal dose surrogate overestimates values of fetal organ dose seen in the J45 phantoms towards the cranial end of the fetus, especially in the later stages of pregnancy. This work supports our previous findings that the J45 pregnant female phantom series offers significate opportunities for gestational age-dependent assessment of fetal organ dose without the need to invoke the uterine wall as a fetal organ surrogate.
Bersweiler, M.*; Sato, Hirokazu*; Adachi, Nozomu*; Todaka, Yoshikazu*; Peral, I.*; Kohlbrecher, J.*; Zaporozhets, V. D.*; Metlov, K. L.*; Michels, A.*; Oba, Yojiro
IUCrJ, 10(4), p.411 - 419, 2023/07
Times Cited Count：2 Percentile：47.77(Chemistry, Multidisciplinary)
100 MeV/nucleonPohl, T.*; Sun, Y. L.*; Obertelli, A.*; Lee, J.*; G
mez-Ramos, M.*; Ogata, Kazuyuki*; Yoshida, Kazuki; Cai, B. S.*; Yuan, C. X.*; Brown, B. A.*; et al.
Physical Review Letters, 130(17), p.172501_1 - 172501_8, 2023/04
Times Cited Count：11 Percentile：88.84(Physics, Multidisciplinary)We report on the first proton-induced single proton- and neutron-removal reactions from the neutron deficient 
O nucleus with large Fermi-surface asymmetry at 100 MeV/nucleon. Our results provide the first quantitative contributions of multiple reaction mechanisms including the quasifree knockout, inelastic scattering, and nucleon transfer processes. It is shown that the inelastic scattering and nucleon transfer, usually neglected at such energy regime, contribute about 50% and 30% to the loosely bound proton and deeply bound neutron removal, respectively.
Matsuya, Yusuke; McMahon, S. J.*; Butterworth, K. T.*; Yachi, Yoshie*; Saga, Ryo*; Sato, Tatsuhiko; Prise, K. M.*
Physics in Medicine & Biology, 68(9), p.095008_1 - 095008_12, 2023/04
Times Cited Count：3 Percentile：57.88(Engineering, Biomedical)Hypoxia induces radioresistance in tumors, leading to malignant progression in intensity-modulated radiation therapy. To date, it has been shown that intercellular signalling between cells positioned inside and outside radiation field impacts on cellular radiosensitivity under hypoxia and normoxia. However, the mechanistic role of intercellular communication in hypoxia remains to be fully understood. In this study, we modelled the cell-killing effects of intercellular signalling in hypoxia to better understand the underlying mechanisms of response. We used the oxygen enhancement ratio (OER) given from early DSB yields and modelled the in- and out-of-field radiosensitivity. As a result, the model analysis provides an mechanistical interpretation that the probability of hits for releasing cell-killing signals is dependent on oxygen. Our data also suggested that the field-type independent OER value, which can be given by uniform-field exposure, can be applied when predicting both in- and out-of-field radiosensitivity. These results would contribute to more precise understanding of intercellular signalling under heterogeneous exposure to intensity-modulated radiation fields.
Ahn, J. K.*; Hasegawa, Shoichi; Imai, Kenichi*; Sako, Hiroyuki; Sato, Susumu; Tanida, Kiyoshi; 10 of others*
Nuclear Instruments and Methods in Physics Research A, 1047, p.167775_1 - 167775_13, 2023/02
Times Cited Count：1 Percentile：0.00(Instruments & Instrumentation) laser stripping at J-PARC RCSSaha, P. K.; Harada, Hiroyuki; Kinsho, Michikazu; Yoneda, Hitoki*; Michine, Yurina*; Sato, Atsushi*; Shibata, Takanori*
Proceedings of 19th Annual Meeting of Particle Accelerator Society of Japan (Internet), p.272 - 276, 2023/01
Sn in concrete rubbleDo, V. K.; Furuse, Takahiro; Ota, Yuki; Iwahashi, Hiroyuki; Hirosawa, Takashi; Watanabe, Masahisa; Sato, Soichi
Journal of Radioanalytical and Nuclear Chemistry, 331(12), p.5631 - 5640, 2022/12
Times Cited Count：4 Percentile：56.38(Chemistry, Analytical)Sn is one of the long-lived fission products that might have been released into the environment after the Fukushima nuclear accident in Japan in 2011. The presence of radionuclides must be monitored for the proper treatment of wastes obtained from decommissioning accident-related nuclear facilities and the surrounding environment. In the work, we propose a reliable method for verifying the presence of Sn in construction materials by combining the HCl-free solid phase extraction on TEVA resin and a selective measurement by inductively coupled plasma tandem mass spectrometry (ICP-MS/MS). The method has been optimized and characterized step by step. More than 95% of chemical recovery was achieved for Sn from typical concrete matrixes. The interference caused by an isobar Te and possible polyatomic interferences from matrixes were effectively suppressed by the developed chemical separation and the tandem MS/MS configuration. The total decontamination factor for the Te interference was of the order of 10
. The estimated method detection limit for Sn in concrete as measured at m/z = 160 was 12.1 pg g
, which is equivalent to 6.1 mBq g.
Yamamoto, Kazami; Kinsho, Michikazu; Hayashi, Naoki; Saha, P. K.; Tamura, Fumihiko; Yamamoto, Masanobu; Tani, Norio; Takayanagi, Tomohiro; Kamiya, Junichiro; Shobuda, Yoshihiro; et al.
Journal of Nuclear Science and Technology, 59(9), p.1174 - 1205, 2022/09
Times Cited Count：7 Percentile：77.01(Nuclear Science & Technology)In the Japan Proton Accelerator Research Complex, the purpose of the 3 GeV rapid cycling synchrotron (RCS) is to accelerate a 1 MW, high-intensity proton beam. To achieve beam operation at a repetition rate of 25 Hz at high intensities, the RCS was elaborately designed. After starting the RCS operation, we carefully verified the validity of its design and made certain improvements to establish a reliable operation at higher power as possible. Consequently, we demonstrated beam operation at a high power, namely, 1 MW. We then summarized the design, actual performance, and improvements of the RCS to achieve a 1 MW beam.
Xu, S.*; Odaira, Takumi*; Sato, Shunsuke*; Xu, X.*; Omori, Toshihiro*; Harjo, S.; Kawasaki, Takuro; Seiner, H.*; Zoubkov
, K.*; Murakami, Yasukazu*; et al.
Nature Communications (Internet), 13, p.5307_1 - 5307_8, 2022/09
Times Cited Count：22 Percentile：81.50(Multidisciplinary Sciences)