Construction of new polygon mesh-type phantoms based on adult Japanese voxel phantoms

Sato, Kaoru; Furuta, Takuya; Satoh, Daiki; Tsuda, Shuichi

PLOS ONE (Internet), 19(10), p.e0309753_1 - e0309753_26, 2024/10

https://doi.org/10.1371/journal.pone.0309753

The authors previously developed the adult male (JM-103) and female (JF-103) voxel phantoms with standard Japanese body sizes for dose assessment of radiation accidents and medical exposures. However, JM-103 and JF-103 were not applicable to dose assessment considering posture at the time of exposure due to limitations in description format and resolution. In this study, we developed the polygon mesh-type adult Japanese phantoms (male: JPM, female: JPF) based on JM-103 and JF-103. The detailed models of skin and lens with radiosensitive regions less than 1 mm thick were incorporated into JPM and JPF. The effective doses, and skin and lens (entire and radiosensitive regions) doses were calculated for external irradiation with photons or electrons in anterior-posterior geometry. It was confirmed that dose analysis results by JPM and JPF were consistent with the previous reports. In the future, we will develop a detailed dose assessment method for individuals, taking into account their postures at the time of exposure, by applying the posture deformation technique currently under development to the JPM and JPF.

and study of biological effects on cancer cells in the presence of metallic materials during radiotherapy

Nagano, Takuya*; Matsuya, Yusuke; Kaida, Atsushi*; Nojima, Hitomi*; Furuta, Takuya; Sato, Kaoru; Yoshimura, Ryoichi*; Miura, Masahiko*

Journal of Radiation Research (Internet), 65(5), p.628 - 639, 2024/09

https://doi.org/10.1093/jrr/rrae062

In X-ray therapy, radiation regimen is planned to eliminate tumors while minimizing side effects on normal tissue. When irradiating the oral cavity, which includes dental metallic crowns, intense mucositis can occasionally be induced. However, the mechanism underlying the radiosensitization remains unclear. In this study, we investigated the radiosensitization mechanism using cell experiments and computational simulations. As a result, the enhancement ratio observed in the cell experiments was 1.2-1.4, which was found to be predominately attributed to local dose increase near metal. On the other hand, as a result of dose evaluation based on CT images as a preclinical test, it was found that the dose increase was underestimated due to the complex anatomical structure of the human body, and microscopic dose evaluation was necessary. This outcome contributes to the precise understanding of side effects on normal cells around metals.

Atmospheric ionizations by solar X-rays, solar protons, and radiation belt electrons in September 2017 space weather event

Murase, Kiyoka*; Kataoka, Ryuho*; Nishiyama, Takanori*; Sato, Kaoru*; Tsutsumi, Masaki*; Tanaka, Yoshimasa*; Ogawa, Yasunobu*; Sato, Tatsuhiko

Space Weather, 21(12), p.e2023SW003651_1 - e2023SW003651_11, 2023/12

https://doi.org/10.1029/2023SW003651

Comprehensive understandings of their global impact on the atmosphere require whole pictures of spatio-temporal distributions of the ionization due to them. We estimate the altitude profiles of the ionization rate during the space weather event occurred in September 2017 by using the Particle and Heavy Ion Transport code System (PHITS) with input of the particle fluxes obtained by satellites. The estimates are then compared with measurements of the ionization altitude, ionization intensity, and electron density by the radars in the polar region such as the PANSY radar at Syowa Station and the EISCAT in Tromso, Norway. We conclude that the PHITS simulation results reproduce those ionizations measured by ground-based instruments with inputs of observed ionization sources by satellites within a factor of 2.

Development plan for coupling technology between high temperature gas-cooled reactor HTTR and hydrogen production facility, 1; Overview of the HTTR heat application test plan to establish high safety coupling technology

Nomoto, Yasunobu; Mizuta, Naoki; Morita, Keisuke; Aoki, Takeshi; Okita, Shoichiro; Ishii, Katsunori; Kurahayashi, Kaoru; Yasuda, Takanori; Tanaka, Masato; Isaka, Kazuyoshi; et al.

Proceedings of 30th International Conference on Nuclear Engineering (ICONE30) (Internet), 7 Pages, 2023/05

Design and actual performance of J-PARC 3 GeV rapid cycling synchrotron for high-intensity operation

Yamamoto, Kazami; Kinsho, Michikazu; Hayashi, Naoki; Saha, P. K.; Tamura, Fumihiko; Yamamoto, Masanobu; Tani, Norio; Takayanagi, Tomohiro; Kamiya, Junichiro; Shobuda, Yoshihiro; et al.

Journal of Nuclear Science and Technology, 59(9), p.1174 - 1205, 2022/09

https://doi.org/10.1080/00223131.2022.2038301

In the Japan Proton Accelerator Research Complex, the purpose of the 3 GeV rapid cycling synchrotron (RCS) is to accelerate a 1 MW, high-intensity proton beam. To achieve beam operation at a repetition rate of 25 Hz at high intensities, the RCS was elaborately designed. After starting the RCS operation, we carefully verified the validity of its design and made certain improvements to establish a reliable operation at higher power as possible. Consequently, we demonstrated beam operation at a high power, namely, 1 MW. We then summarized the design, actual performance, and improvements of the RCS to achieve a 1 MW beam.

Variation of internal doses caused by differences in physical characteristics between the average Japanese and the ICRP's reference man which is based on the standard data of Caucasians in the dosimetric methodology in conformity to the 2007 Recommendations

Manabe, Kentaro; Sato, Kaoru; Takahashi, Fumiaki

Journal of Nuclear Science and Technology, 59(5), p.656 - 664, 2022/05

https://doi.org/10.1080/00223131.2021.1997663

It is known that internal doses depend on the physical characteristics of an evaluation subject. Internal dose coefficients provided by the International Commission on Radiological Protection (ICRP) are evaluated using the characteristics of the standard Caucasian. It is important to grasp the variations of doses due to the differences in characteristics between Japanese and Caucasian when the dose coefficients of ICRP are applied to Japanese. This study evaluated dose coefficients using specific absorbed fraction (SAF) data based on the average adult Japanese physique which was developed by modification of the existing Japanese SAF data with additional calculations to make the existing data fit to the current dosimetric methodology of ICRP and compared them to those provided by ICRP. As a result, the discrepancies in dose coefficients were smaller than plus or minus 10% in most intake conditions. However, some intake conditions indicated varieties over 40% due to the differences in organ masses, amount of adipose tissues around the thoracic cavity, and so on. This information is useful in application of ICRP's dose coefficients to population of which physical characteristics are different from those of Caucasian. Further, the Japanese SAF data is published as an appendix of this paper.

Effective dose coefficients for internal exposure dose assessment in accordance with ICRP 2007 recommendations (Contract research)

Takahashi, Fumiaki; Manabe, Kentaro; Sato, Kaoru

JAEA-Review 2020-068, 114 Pages, 2021/03

JAEA-Review-2020-068.pdf:2.61MB

Radiation safety regulations have been currently established based on the 1990Recommendation by the International Commission on Radiological Protection (ICRP) in Japan. Meanwhile, ICRP released the 2007 Recommendation that replaces the 1990 Recommendation. Thus, the Radiation Council, which is established under the Nuclear Regulation Authority (NRA), has made discussions to incorporate the purpose of the 2007 Recommendation into Japanese regulations for radiation safety. As ICRP also has published effective dose coefficients for internal exposure assessment in accordance with the 2007recommendation, the technical standards are to be revised for the internal exposure assessment method in Japan. Currently, not all of the effective doses have been published to revise concentration limits for internal exposure protections of workers and public. The published effective dose coefficients are applied to radionuclides which are important in radiation protection for internal exposure of a worker. Thus, we review new effective dose coefficients as well as basic dosimetry models and data based upon Occupational Intakes of Radionuclides (OIR) parts 2, 3 and 4 that have been published from 2016 to 2019 by ICRP. In addition, issues are sorted out to provide information for revision of the technical standards for internal exposure assessment based on the 2007 Recommendations in future.

Transient ionization of the mesosphere during auroral breakup; Arase satellite and ground-based conjugate observations at Syowa Station

Kataoka, Ryuho*; Nishiyama, Takanori*; Tanaka, Yoshimasa*; Kadokura, Akira*; Uchida, Herbert Akihito*; Ebihara, Yusuke*; Ejiri, Mitsumu*; Tomikawa, Yoshihiro*; Tsutsumi, Masaki*; Sato, Kaoru*; et al.

Earth, Planets and Space (Internet), 71(1), p.9_1 - 9_10, 2019/12

https://doi.org/10.1186/s40623-019-0989-7

Transient ionization of the mesosphere was detected at around 65 km altitude during the isolated auroral expansion occurred at 2221-2226 UT on June 30, 2017. A general-purpose Monte Carlo particle transport code PHITS suggested that significant ionization is possible in the middle atmosphere due to auroral X-rays from the auroral electrons of 10 keV.

Estimating internal dose coefficients of short-lived radionuclides in accordance with ICRP 2007 Recommendations

Manabe, Kentaro; Sato, Kaoru; Takahashi, Fumiaki

Journal of Nuclear Science and Technology, 56(5), p.385 - 393, 2019/05

https://doi.org/10.1080/00223131.2019.1585988

At high energy accelerator facilities, various radionuclides are produced by nuclear reactions of high energy particles with structure and/or ambient air of the facilities. Consequently, the radionuclides are potential sources of internal exposure for works of the facilities. However, the International Commission on Radiological Protection (ICRP) do not provide dose coefficients, which are committed effective doses per intake, for the short-lived radionuclides whose half-lives are shorter than 10 minutes in accordance with the ICRP 2007 Recommendations. Then, we estimated the dose coefficients for inhalation and ingestion of these short-lived radionuclides in accordance with the ICRP 2007 Recommendations. In addition, we compared the dose coefficients with those in accordance with the ICRP 1990 Recommendations. As a result, a decreasing tendency was shown in the dose coefficients for inhalation cases; an increasing tendency was observed in those for ingestion cases. It was found that these changes in dose coefficients were mainly caused by the revision of the dose calculation procedures, alimentary tract models. The result of this study will be useful for planning of radiation protection at the high energy facilities.

Materials and Life Science Experimental Facility at the Japan Proton Accelerator Research Complex, 3; Neutron devices and computational and sample environments

Sakasai, Kaoru; Sato, Setsuo*; Seya, Tomohiro*; Nakamura, Tatsuya; To, Kentaro; Yamagishi, Hideshi*; Soyama, Kazuhiko; Yamazaki, Dai; Maruyama, Ryuji; Oku, Takayuki; et al.

Quantum Beam Science (Internet), 1(2), p.10_1 - 10_35, 2017/09

https://doi.org/10.3390/qubs1020010

Neutron devices such as neutron detectors, optical devices including supermirror devices and He neutron spin filters, and choppers are successfully developed and installed at the Materials Life Science Facility (MLF) of the Japan Proton Accelerator Research Complex (J-PARC), Tokai, Japan. Four software components of MLF computational environment, instrument control, data acquisition, data analysis, and a database, have been developed and equipped at MLF. MLF also provides a wide variety of sample environment options including high and low temperatures, high magnetic fields, and high pressures. This paper describes the current status of neutron devices, computational and sample environments at MLF.