Polyelectrolyte-protein synergism; pH-responsive polyelectrolyte/insulin complexes as versatile carriers for targeted protein and drug delivery

Murmiliuk, A.*; Iwase, Hiroki*; Kang, J.-J.*; Mohanakumar, S.*; Appavou, M.-S.*; Wood, K.*; Almsy, L.*; Len, A.*; Schwrzer, K.*; Allgaier, J.*; et al.

Journal of Colloid and Interface Science, 665, p.801 - 813, 2024/07

https://doi.org/10.1016/j.jcis.2024.03.156

The complexity of protein structure limits our ability to predict and tune the properties of the formed nanoparticles. The goal of our research is to elucidate the key triggers of the morphological transition in protein/PE complexes, evaluate their encapsulation efficacy, and assess particle stability by the systematic study of complexes formed by block copolymers with proteins and ionic drugs. We demonstrated that copolymers consisting of PE and neutral hydrophilic block co-assemble with insulin at pH values close to the protein isoelectric point. The insulin arrangement within the particle is controlled by electrostatic forces between protein molecules, and the morphology of the formed particles can be tuned by varying pH and ionic strength.

decay of exotic P and S isotopes with neutron number near 28

Tripathi, V.*; Bhattacharya, S.*; Rubino, E.*; Benetti, C.*; Perello, J. F.*; Tabor, S. L.*; Liddick, S. N.*; Bender, P. C.*; Carpenter, M. P.*; Carroll, J. J.*; et al.

Physical Review C, 106(6), p.064314_1 - 064314_14, 2022/12

https://doi.org/10.1103/PhysRevC.106.064314

no abstracts in English

Multi-methodical study of the Ti, Fe and Fe distribution in chevkinite-subgroup minerals; X-ray diffraction, neutron diffraction, Fe Mssbauer spectroscopy and electron-microprobe analyses

Nagashima, Mariko*; Armbruster, T.*; Akasaka, Masahide*; Sano, Asami; Nishio-Hamane, Daisuke*; Malsy, A.*; Imaoka, Teruyoshi*; Nakashima, Kazuo*

Physics and Chemistry of Minerals, 47(6), p.29_1 - 29_18, 2020/06

https://doi.org/10.1007/s00269-020-01096-5

Three non-metamict chevkinite-subgroup minerals, from Cape Ashizuri, Japan, Tangir Valley, Diamar District, Pakistan and Haramosh Mts., Skardu district, Pakistan, were studied by crystal chemical techniques. Powder X-ray diffraction and transmission electron microscopic observations confirmed well crystalline samples. Electron-microprobe analyses indicated the general composition known for chevkinite-(Ce). Site scattering values determined by single-crystal X-ray structure refinements suggested assignment of subordinate Nb to the octahedral M3 and M4 sites, minor Th to M1 for the Ashizuri sample and minor Mg to M1 for both samples from Pakistan. Neutron time-of-flight powder diffraction studies were applied to determine the Ti/Fe distribution among octahedral sites for all samples and Mossbauer spectroscopy served for the Fe valence assignment at the four octahedral sites. The dominant iron valence at M1 of the Haramosh sample is ferric whereas for samples Nos. 1 and 2 iron is ferrous.

-decay properties of Fr

Ghys, L.*; Andreyev, A. N.; Huyse, M.*; Van Duppen, P.*; Antalic, S.*; Barzakh, A.*; Capponi, L.*; Cocolios, T. E.*; Cubiss, J.*; Derkx, X.*; et al.

Physical Review C, 100(5), p.054310_1 - 054310_13, 2019/11

https://doi.org/10.1103/PhysRevC.100.054310

Fine structure in the decay of At

Cubiss, J. G.*; Andreyev, A. N.; Barzakh, A. E.*; Andel, B.*; Antalic, S.*; Cocolios, T. E.*; Day Goodacre, T.*; Fedorov, D. V.*; Fedosseev, V. N.*; Ferrer, R.*; et al.

Physical Review C, 99(6), p.064317_1 - 064317_6, 2019/06

https://doi.org/10.1103/PhysRevC.99.064317

An decay of At was studied at the CERN-ISOLDE facility using a laser-ionization technique. Coincidence - data were collected for the first time and a more precise half-life value of T = 1.27(6) s was measured. A new -decay scheme was deduced based on the fine-structure of the decay. The results lead to a preferred spin and parity assignment of J = (3) for the ground state of At; however, J = (2) cannot be fully excluded.

A New detector system for the measurement of high-energy prompt -rays for low-energy neutron induced fission

Makii, Hiroyuki; Nishio, Katsuhisa; Hirose, Kentaro; Orlandi, R.; Lguillon, R.*; Ogawa, Tatsuhiko; Soldner, T.*; Hambsch, F.-J.*; Ache, M.*; Astier, A.*; et al.

Nuclear Instruments and Methods in Physics Research A, 906, p.88 - 96, 2018/10

https://doi.org/10.1016/j.nima.2018.07.055

We have developed a new setup to measure prompt fission -ray spectra in neutron induced fission up to energies sufficient to reveal the structure associated with giant dipole resonances of fission fragments. The setup consists of multi-wire proportional counters, to detect both fission fragments in coincidence, and two large volume (101.6 mm in diameter and 127.0 mm in length) LaBr(Ce) scintillators, to measure the -rays. The setup was used to obtain the prompt fission -ray spectrum for thermal neutron induced fission of U at the PF1B cold-neutron beam facility of the Institut Laue-Langevin, Grenoble, France. We have successfully measured the -ray spectrum up to energies of about 20 MeV, what extends the currently known -ray spectrum limit to higher energies by approximately a factor of two.

Detailed -decay study of Tl

Andel, B.*; Andreyev, A. N.; Antalic, S.*; Barzakh, A.*; Bree, N.*; Cocolios, T. E.*; Comas, V. F.*; Diriken, J.*; Elseviers, J.*; Fedorov, D. V.*; et al.

Physical Review C, 96(5), p.054327_1 - 054327_11, 2017/12

https://doi.org/10.1103/PhysRevC.96.054327

Measurement of high-energy prompt -rays from neutron induced fission of U-235

Makii, Hiroyuki; Nishio, Katsuhisa; Hirose, Kentaro; Orlandi, R.; Lguillon, R.; Ogawa, Tatsuhiko; Soldner, T.*; Hambsch, F.-J.*; Astier, A.*; Pollitt, A.*; et al.

EPJ Web of Conferences, 146, p.04036_1 - 04036_4, 2017/09

https://doi.org/10.1051/epjconf/201714604036

The measurement of the prompt fission -ray spectrum (PFGS) is quite important to study the de-excitation process of neutron-rich fission fragments as well as to generate data required to design a generation-IV reactors. The PFGS measured for spontaneous fission of Cf shows a broad hump at energies more than 8 MeV. This is interpreted as a giant dipole resonance (GDR) of the fragments centered around 15 MeV. To understand how the GDR is populated in the fission process, one needs to measure the PFGS for the reactions with the mass yields different from the spontaneous fission of Cf, such as (n,f). The measurements of the PFGS for (n,f), however, are limited less than 9 MeV even in the recent experiment. This prompts us to make a new measurement to extend the know PFGS up to 20 MeV. The measurement has been carried out at the PF1B beam line of Institut Laue-Langevin. In this contribution we will present the results obtained the measurement.

Stability and synthesis of superheavy elements; Fighting the battle against fission - Example of No

Lopez-Martens, A.*; Henning, G.*; Khoo, T. L.*; Seweryniak, D.*; Alcorta, M.*; Asai, Masato; Back, B. B.*; Bertone, P. F.*; Boilley, D.*; Carpenter, M. P.*; et al.

EPJ Web of Conferences, 131, p.03001_1 - 03001_6, 2016/12

https://doi.org/10.1051/epjconf/201613103001

Fission barrier height and its angular-momentum dependence have been measured for the first time in the nucleus with the atomic number greater than 100. The entry distribution method, which can determine the excitation energy at which fission starts to dominate the decay process, was applied to No. The fission barrier of No was found to be 6.6 MeV at zero spin, indicating that the No is strongly stabilized by the nuclear shell effects.

Population and decay of a = 8 two-quasineutron isomer in Pu

Hota, S.*; Tandel, S.*; Chowdhury, P.*; Ahmad, I.*; Carpenter, M. P.*; Chiara, C. J.*; Greene, J. P.*; Hoffman, C. R.*; Jackson, E. G.*; Janssens, R. V. F.*; et al.

Physical Review C, 94(2), p.021303_1 - 021303_5, 2016/08

https://doi.org/10.1103/PhysRevC.94.021303

The decay of a = 8 isomer in Pu and the collective band structure populating the isomer are studied using deep inelastic excitations with Ti and Pb beams, respectively. Precise measurements of branching ratios in the band confirm a clean 9/2[734]7/2[624] for the isomer, validating the systematics of K = 8 two-quasineutron isomers observed in even-, = 150 isotones. These isomers around the deformed shell gap at = 152 provide critical benchmarks for theoretical predictions of single-particle energies in this gateway region to superheavy nuclei.