Toyoda, Satoshi*; Yamamoto, Tomoki*; Yoshimura, Masashi*; Sumida, Hirosuke*; Mineoi, Susumu*; Machida, Masatake*; Yoshigoe, Akitaka; Suzuki, Satoru*; Yokoyama, Kazushi*; Ohashi, Yuji*; et al.
Vacuum and Surface Science, 64(2), p.86 - 91, 2021/02
We have developed measurement and analysis techniques in X-ray photoelectron spectroscopy. To begin with, time-division depth profiles of gate stacked film interfaces have been achieved by NAP-HARPES (Near Ambient Pressure Hard X-ray Angle-Resolved Photo Emission Spectroscopy) data. We then have promoted our methods to quickly perform peak fittings and depth profiling from time-division ARPES data, which enables us to realize 4D-XPS analysis. It is found that the traditional maximum entropy method (MEM) combined with Jackknife averaging of sparse modeling in NAP-HARPES data is effective to perform dynamic measurement of depth profiles with high precision.
Tanaka, Yoshihiro*; Kametaka, Masao*; Okazaki, Kazuhiko*; Suzuki, Kazushige*; Seshimo, Kazuyoshi; Aoki, Kazuhiro; Shimada, Koji; Watanabe, Takahiro; Nakayama, Kazuhiko
Oyo Chishitsu, 59(1), p.13 - 27, 2018/04
This paper aims to develop a methodology for understanding the fault activity by observing exposed fault planes without covering younger strata. Based on purpose, faults developed in relatively homogeneous rocks such granitic types are investigated as follows; Gosuke Dam upstream outcrop of Gosukebashi Fault and Funasaka-nishi outcrop of Rokkou Fault were selected for the study of an active fault; and K-3 outcrop of Rokkou Houraikyo Fault was chosen for a non-active fault.
Nakajima, Kenji; Kawakita, Yukinobu; Ito, Shinichi*; Abe, Jun*; Aizawa, Kazuya; Aoki, Hiroyuki; Endo, Hitoshi*; Fujita, Masaki*; Funakoshi, Kenichi*; Gong, W.*; et al.
Quantum Beam Science (Internet), 1(3), p.9_1 - 9_59, 2017/12
The neutron instruments suite, installed at the spallation neutron source of the Materials and Life Science Experimental Facility (MLF) at the Japan Proton Accelerator Research Complex (J-PARC), is reviewed. MLF has 23 neutron beam ports and 21 instruments are in operation for user programs or are under commissioning. A unique and challenging instrumental suite in MLF has been realized via combination of a high-performance neutron source, optimized for neutron scattering, and unique instruments using cutting-edge technologies. All instruments are/will serve in world-leading investigations in a broad range of fields, from fundamental physics to industrial applications. In this review, overviews, characteristic features, and typical applications of the individual instruments are mentioned.
Sakasai, Kaoru; Sato, Setsuo*; Seya, Tomohiro*; Nakamura, Tatsuya; To, Kentaro; Yamagishi, Hideshi*; Soyama, Kazuhiko; Yamazaki, Dai; Maruyama, Ryuji; Oku, Takayuki; et al.
Quantum Beam Science (Internet), 1(2), p.10_1 - 10_35, 2017/09
Neutron devices such as neutron detectors, optical devices including supermirror devices and He neutron spin filters, and choppers are successfully developed and installed at the Materials Life Science Facility (MLF) of the Japan Proton Accelerator Research Complex (J-PARC), Tokai, Japan. Four software components of MLF computational environment, instrument control, data acquisition, data analysis, and a database, have been developed and equipped at MLF. MLF also provides a wide variety of sample environment options including high and low temperatures, high magnetic fields, and high pressures. This paper describes the current status of neutron devices, computational and sample environments at MLF.
Oku, Takayuki; Nakamura, Mitsutaka; Sakai, Kenji; Teshigawara, Makoto; Hideki, Tatsumoto*; Yonemura, Masao*; Suzuki, Junichi*; Arai, Masatoshi*
JAEA-Conf 2015-002, 660 Pages, 2016/02
The twenty first meeting of the International Collaboration on Advanced Neutron Source (ICANS-XXI) was held at Ibaraki Prefectural Culture Center in Mito from 29 September to 3 October 2014. It was hosted by Japan Atomic Energy Agency (JAEA), High Energy Accelerator Research Organization (KEK) and Comprehensive Research Organization for Science and Society (CROSS). In the meeting, new science and technology in the new era with the high power neuron sources were discussed in mostly "workshop style" sessions. In each session, various kinds of issues related to not only the hardware, but also the software and even radiation safety were discussed with the keyword of "INTERFACE". More than 200 Papers were presented in the meeting and 72 contributed papers are compiled in the proceedings.
Kitayama, Takumi*; Nakajima, Kaoru*; Suzuki, Motofumi*; Narumi, Kazumasa; Saito, Yuichi; Matsuda, Makoto; Sataka, Masao*; Tsujimoto, Masahiko*; Isoda, Shoji*; Kimura, Kenji*
Nuclear Instruments and Methods in Physics Research B, 354, p.183 - 186, 2015/07
Suzuki, Masao*; Funayama, Tomoo; Yokota, Yuichiro; Muto, Yasuko*; Suzuki, Michiyo; Ikeda, Hiroko; Hattori, Yuya; Kobayashi, Yasuhiko
JAEA-Review 2014-050, JAEA Takasaki Annual Report 2013, P. 78, 2015/03
We have been studying the radiation-quality dependent bystander cellular effects, such as cell killing, mutation induction and chromosomal damage, using heavy-ion microbeams with different ion species. This year we focused on the ion-species dependent bystander mutagenic effect on locus in normal human fibroblasts. The confluent culture were irradiated using a 256 (1616)-cross-stripe method using C, Ne and Ar microbeam. Gene mutation on locus was detected with 6-thioguanine resistant clones. The mutation frequency in cells irradiated with C-ion microbeams was 6 times higher than that of non-irradiated control cells and of the sample treated with specific inhibitor of gap-junction cell-to-cell communication. On the other hand, no enhanced mutation frequencies were observed in cells irradiated with either Ne- or Ar-ion microbeams. There is clear evidence that the bystander mutagenic effect via gap-junction communication depends on radiation quality.
Autsavapromporn, N.*; Plante, I.*; Liu, C.*; Konishi, Teruaki*; Usami, Noriko*; Funayama, Tomoo; Azzam, E.*; Murakami, Takeshi*; Suzuki, Masao*
International Journal of Radiation Biology, 91(1), p.62 - 70, 2015/01
Radiation-induced bystander effects have important implications in radiotherapy. Their persistence in normal cells may contribute to risk of health hazards, including cancer. This study investigates the role of radiation quality and gap junction intercellular communication (GJIC) in the propagation of harmful effects in progeny of bystander cells. Confluent human skin fibroblasts were exposed to microbeam radiations with different linear energy transfer (LET) by which 0.0360.4% of the cells were directly targeted by radiation. Following 20 population doublings, the cells were harvested and assayed for micronucleus formation, gene mutation and protein oxidation. The results showed that expression of stressful effects in the progeny of bystander cells is dependent on LET.
Shiraishi, Iyo; Suzuki, Masao*; Shikazono, Naoya; Fujii, Kentaro; Yokoya, Akinari
Journal of Radiation Research, 55(Suppl.1), p.i92 - i93, 2014/03
Shiina, Takuya*; Watanabe, Ritsuko; Suzuki, Masao*; Yokoya, Akinari
Journal of Radiation Research, 55(Suppl.1), p.i15 - i16, 2014/03
Suzuki, Masao*; Autsavapromporn, N.*; Usami, Noriko*; Funayama, Tomoo; Plante, I.*; Yokota, Yuichiro; Muto, Yasuko*; Suzuki, Michiyo; Ikeda, Hiroko; Hattori, Yuya; et al.
Journal of Radiation Research, 55(Suppl.1), P. i54, 2014/03
Autsavapromporn, N.*; Suzuki, Masao*; Funayama, Tomoo; Usami, Noriko*; Plante, I.*; Yokota, Yuichiro; Muto, Yasuko*; Ikeda, Hiroko; Kobayashi, Katsumi*; Kobayashi, Yasuhiko; et al.
Radiation Research, 180(4), p.367 - 375, 2013/10
We investigated the role of gapjunction intercellular communication (GJIC) in the propagation of stressful effects in confluent normal human fibroblast cultures wherein only 0.036-0.144% of cells in the population were traversed by primary radiation tracks. Confluent cells were exposed to graded doses from X ray, carbon ion, neon ion or argon ion microbeams in the presence or absence of an inhibitor of GJIC. After 4 h incubation, the cells were assayed for micronucleus (MN) formation. Micronuclei were induced in a greater fraction of cells than expected based on the fraction of cells targeted by primary radiation, and the effect occurred in a dose-dependent manner with any of the radiation sources. Interestingly, the inhibition of GJIC depressed the enhancement of MN formation in bystander cells from cultures exposed to high-LET radiation but not low-LET radiation. The results highlight the important role of radiation quality and dose in the observed effects.
Xu, P. G.; Tomota, Yo*; Vogel, S. C.*; Suzuki, Tetsuya*; Yonemura, Masao*; Kamiyama, Takashi*
Reviews on Advanced Materials Science, 33(5), p.389 - 395, 2013/08
Shiina, Takuya; Watanabe, Ritsuko; Shiraishi, Iyo; Suzuki, Masao*; Sugaya, Yuki; Fujii, Kentaro; Yokoya, Akinari
Radiation and Environmental Biophysics, 52(1), p.99 - 112, 2013/03
Nobuta, Yuji*; Yamauchi, Yuji*; Hino, Tomoaki*; Akamaru, Satoshi*; Hatano, Yuji*; Matsuyama, Masao*; Suzuki, Satoshi; Akiba, Masato
Fusion Engineering and Design, 87(7-8), p.1070 - 1073, 2012/08
Ushigome, Takeshi*; Shikazono, Naoya; Fujii, Kentaro; Watanabe, Ritsuko; Suzuki, Masao*; Tsuruoka, Chizuru*; Tauchi, Hiroshi*; Yokoya, Akinari
Radiation Research, 177(5), p.614 - 627, 2012/05
The yield of DNA damage produced in fully hydrated plasmid DNA films has been investigated to determine the linear energy transfer (LET) dependence of damage induction. The yield of single strand breaks (SSBs) with increasing LET levels of He, C and Ne ions. On the other hand, the yields of prompt double strand breaks (DSBs) increased with increasing LET. SSBs were additionally induced by treatment with base excision repair proteins, glycosylases, indicating that base lesions are produced in the hydrated DNA. This result shows that nucleobase lesions are produced via both chemical reactions with diffusible water radicals and direct energy deposition onto DNA or the hydrated layer. The yield of SSBs or DSBs observed by enzymatic treatment notably decreased with increasing LET. These results indicated that higher LET ions preferentially produce a complex type of damage that might compromise the activities of the proteins used in this study.
Sato, Tatsuhiko; Watanabe, Ritsuko; Kase, Yuki*; Tsuruoka, Chizuru*; Suzuki, Masao*; Furusawa, Yoshiya*; Niita, Koji*
Radiation Protection Dosimetry, 143(2-4), p.491 - 496, 2011/02
We reanalyzed the survival fraction data, using the microdosimetric-kinetic (MK) model implemented in the PHITS code. It is found from the analysis that the MK model successfully accounts for the cell survival-fractions under a variety of irradiation conditions, using only y* parameter.
Inoue, Naoko; Kawakubo, Yoko; Seya, Michio; Suzuki, Mitsutoshi; Kuno, Yusuke; Senzaki, Masao
Kaku Busshitsu Kanri Gakkai (INMM) Nihon Shibu Dai-31-Kai Nenji Taikai Rombunshu (CD-ROM), 9 Pages, 2010/12
The GIF Proliferation Resistance and Physical Protection (PR&PP) evaluation methodology has been developed for GEN IV nuclear energy systems under the international consensus. The PR&PP WG activities include development of the measures and metrics; establishment of the framework of PR&PP evaluation, the demonstration study using Example Sodium Fast Reactor (ESFR), which included the development of three evaluation approaches; the Case study using ESFR and four kinds of threat scenarios; the joint study with GIF System Steering Committees (SSCs) of the six reactor design concepts; and the harmonization study with the IAEA's International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). This paper reviews the status of GIF PR&PP studies and identifies the challenges and directions for applying the methodology to evaluate future nuclear energy systems in Japan.
Suzuki, Tatsuya*; Nomura, Masao*; Fujii, Yasuhiko*; Ikeda, Atsushi; Takaoka, Toru*; Oguma, Koichi*
Nihon Ion Kokan Gakkai-Shi, 21(3), p.328 - 333, 2010/09
Zinc isotope fractionation in an anion exchange resin has been investigated in hydrochloric acid solution by chromatographic technique. It was found that the heavier zinc isotopes were located disproportionately in the solution phase. The isotope fractionation coefficient was varied from the order of 10 to 10 depending on the hydrochloric acid concentration. The maximum isotope fractionation coefficient was obtained in 1 hydrochloric acid, while the distribution coefficient of zinc became maximum at around 2 hydrochloric acid. This difference has been further discussed based on the calculated speciation and structural information derived from X-ray absorption spectroscopy.
Inoue, Naoko; Kaji, Naoya; Suda, Kazunori; Kawakubo, Yoko; Suzuki, Mitsutoshi; Koyama, Tomozo; Kuno, Yusuke; Senzaki, Masao
Proceedings of INMM 51st Annual Meeting (CD-ROM), 10 Pages, 2010/07