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Journal Articles

Role of advection in atmospheric ammonia; A Case study at a Japanese lake basin influenced by agricultural ammonia sources

Kubota, Tomohiro; Kuroda, Hisao*; Watanabe, Mirai*; Takahashi, Akiko*; Nakazato, Ryoji*; Tarui, Mika*; Matsumoto, Shunichi*; Nakagawa, Keita*; Numata, Yasuko*; Ouchi, Takao*; et al.

Atmospheric Environment, 243, p.117856_1 - 117856_9, 2020/12

 Times Cited Count:2 Percentile:10.2(Environmental Sciences)

The dry and wet depositions of atmospheric ammonia (NH$$_{3}$$) is one of the important pathways of nitrogen loads to aquatic ecosystems. Crop and livestock agriculture, one of the largest emitters of NH$$_{3}$$ in Asian countries, are known to cause high spatial and seasonal variation of NH$$_{3}$$ and influence the surrounding lake basin areas via its dry and wet deposition. However, the spatial characteristics of the NH$$_{3}$$ concentration in basin scale are not completely understood for regulation in NH$$_{3}$$ emission. Here we aim to clarify dominant factors of spatial and seasonal variations of the NH$$_{3}$$ concentration in a eutrophic lake basin surrounded by agricultural areas in Japan. Passive sampling over various land use categories in the basin was conducted at 36 sites in total from October 2018 to January 2020. Interestingly, the observed NH$$_{3}$$ concentration near the livestock houses were higher in winter than summer, which was inconsistent with knowledge of seasonal changes of current NH$$_{3}$$ emission inventory based on temperature-driven volatilization process. Comparing monthly NH$$_{3}$$ concentrations with various meteorological factors, we suggested the importance of seasonal advection of NH$$_{3}$$ from high emission sources to which has been rarely paid attention by the previous past studies. As for this, should be considered for lake ecosystem management since deposition of NH$$_{3}$$ is known to be closely related to the ecological processes such as phytoplankton blooming.

Journal Articles

From laboratory to field; ${it OsNRAMP5}$-knockdown rice is a promising candidate for Cd phytoremediation in paddy fields

Takahashi, Ryuichi*; Ishimaru, Yasuhiro*; Shimo, H.*; Bashir, K.*; Senoura, Takeshi*; Sugimoto, Kazuhiko*; Ono, Kazuko*; Suzui, Nobuo; Kawachi, Naoki; Ishii, Satomi; et al.

PLOS ONE (Internet), 9(6), p.e98816_1 - e98816_7, 2014/06

 Times Cited Count:51 Percentile:86.87(Multidisciplinary Sciences)

Journal Articles

Development of prediction models for radioactive caesium distribution within the 80-km radius of the Fukushima Daiichi Nuclear Power Plant

Kinase, Sakae; Takahashi, Tomoyuki*; Sato, Satoshi; Sakamoto, Ryuichi*; Saito, Kimiaki

Radiation Protection Dosimetry, 160(4), p.318 - 321, 2014/00

 Times Cited Count:32 Percentile:92.37(Environmental Sciences)

Journal Articles

Recent advances in the biology of heavy-ion cancer therapy

Hamada, Nobuyuki*; Imaoka, Tatsuhiko*; Masunaga, Shinichiro*; Ogata, Toshiyuki*; Okayasu, Ryuichi*; Takahashi, Akihisa*; Kato, Takamitsu*; Kobayashi, Yasuhiko; Onishi, Takeo*; Ono, Koji*; et al.

Journal of Radiation Research, 51(4), p.365 - 383, 2010/07

 Times Cited Count:109 Percentile:90.99(Biology)

Journal Articles

Economic scale of nuclear application

Saito, Shinzo*; Tanaka, Ryuichi*; Kume, Tamikazu; Inoue, Tomio*; Takahashi, Shoji*

Genshiryoku eye, 54(5), p.34 - 41, 2008/05

no abstracts in English

Journal Articles

The H-Invitational Database (H-InvDB); A Comprehensive annotation resource for human genes and transcripts

Yamasaki, Chisato*; Murakami, Katsuhiko*; Fujii, Yasuyuki*; Sato, Yoshiharu*; Harada, Erimi*; Takeda, Junichi*; Taniya, Takayuki*; Sakate, Ryuichi*; Kikugawa, Shingo*; Shimada, Makoto*; et al.

Nucleic Acids Research, 36(Database), p.D793 - D799, 2008/01

 Times Cited Count:51 Percentile:71.37(Biochemistry & Molecular Biology)

Here we report the new features and improvements in our latest release of the H-Invitational Database, a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of fulllength cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 protein-coding and 642 non-protein-coding loci; 858 transcribed loci overlapped with predicted pseudogenes.

Journal Articles

Overview of national centralized tokamak program; Mission, design and strategy to contribute ITER and DEMO

Ninomiya, Hiromasa; Akiba, Masato; Fujii, Tsuneyuki; Fujita, Takaaki; Fujiwara, Masami*; Hamamatsu, Kiyotaka; Hayashi, Nobuhiko; Hosogane, Nobuyuki; Ikeda, Yoshitaka; Inoue, Nobuyuki; et al.

Journal of the Korean Physical Society, 49, p.S428 - S432, 2006/12

To contribute DEMO and ITER, the design to modify the present JT-60U into superconducting coil machine, named National Centralized Tokamak (NCT), is being progressed under nationwide collaborations in Japan. Mission, design and strategy of this NCT program is summarized.

Journal Articles

Application of supercritical fluid extraction to metal separation in the field of nuclear technology

Meguro, Yoshihiro; Tomioka, Osamu; Takahashi, Kuniaki; Wada, Ryutaro*; Yamamoto, Seiichi*; Fukuzato, Ryuichi*

Proceedings of 8th International Symposium on Supercritical Fluids (ISSF 2006) (CD-ROM), 6 Pages, 2006/11

A large-scale apparatus having a reaction vessel of ca. 4000 cm$$^3$$ was developed for supercritical CO$$_2$$ leaching. An ultrasonic wave oscillator, stirring device, and piston compressor were equipped to the apparatus to enhance mass transfer rate of substances in supercritical CO$$_2$$. A sea sand sample, an incinerated ash sample, and a porous alumina brick sample, in which uranium oxide was adsorbed, were prepared as simulated samples of radioactive wastes and uranium was tried to remove from these samples to supercritical CO$$_2$$ including nitric acid - tri-n-butyl phosphate complex as a reactant using the apparatus. By several times of the uranium separation, more than 99% of uranium was removed from the sea sand sample and the ash sample. When the mass transfer enhanced system was operated, it was confirmed that separation efficiency of uranium was improved and then 99% of uranium could be removed form the ash sample.

Journal Articles

Overview of the national centralized tokamak programme

Kikuchi, Mitsuru; Tamai, Hiroshi; Matsukawa, Makoto; Fujita, Takaaki; Takase, Yuichi*; Sakurai, Shinji; Kizu, Kaname; Tsuchiya, Katsuhiko; Kurita, Genichi; Morioka, Atsuhiko; et al.

Nuclear Fusion, 46(3), p.S29 - S38, 2006/03

 Times Cited Count:13 Percentile:41.84(Physics, Fluids & Plasmas)

The National Centralized Tokamak (NCT) facility program is a domestic research program for advanced tokamak research to succeed JT-60U incorporating Japanese university accomplishments. The mission of NCT is to establish high beta steady-state operation for DEMO and to contribute to ITER. The machine flexibility and mobility is pursued in aspect ratio and shape controllability, feedback control of resistive wall modes, wide current and pressure profile control capability for the demonstration of the high-b steady state.

Journal Articles

Engineering design and control scenario for steady-state high-beta operation in national centralized tokamak

Tsuchiya, Katsuhiko; Akiba, Masato; Azechi, Hiroshi*; Fujii, Tsuneyuki; Fujita, Takaaki; Fujiwara, Masami*; Hamamatsu, Kiyotaka; Hashizume, Hidetoshi*; Hayashi, Nobuhiko; Horiike, Hiroshi*; et al.

Fusion Engineering and Design, 81(8-14), p.1599 - 1605, 2006/02

 Times Cited Count:1 Percentile:9.98(Nuclear Science & Technology)

no abstracts in English

Journal Articles

Design study of national centralized tokamak facility for the demonstration of steady state high-$$beta$$ plasma operation

Tamai, Hiroshi; Akiba, Masato; Azechi, Hiroshi*; Fujita, Takaaki; Hamamatsu, Kiyotaka; Hashizume, Hidetoshi*; Hayashi, Nobuhiko; Horiike, Hiroshi*; Hosogane, Nobuyuki; Ichimura, Makoto*; et al.

Nuclear Fusion, 45(12), p.1676 - 1683, 2005/12

 Times Cited Count:15 Percentile:45.55(Physics, Fluids & Plasmas)

Design studies are shown on the National Centralized Tokamak facility. The machine design is carried out to investigate the capability for the flexibility in aspect ratio and shape controllability for the demonstration of the high-beta steady state operation with nation-wide collaboration, in parallel with ITER towards DEMO. Two designs are proposed and assessed with respect to the physics requirements such as confinement, stability, current drive, divertor, and energetic particle confinement. The operation range in the aspect ratio and the plasma shape is widely enhanced in consistent with the sufficient divertor pumping. Evaluations of the plasma performance towards the determination of machine design are presented.

Oral presentation

The Radiosesitization effect of Hsp90 inhibitor 17AAG in ${it in vivo}$ model

Takahashi, Momoko; Noguchi, Miho; Hirakawa, Hirokazu*; Okayasu, Ryuichi*

no journal, , 

Ionizing radiation has been widely used as a tool for tumor treatment. However, there are still difficulties to treat the solid tumor with only irradiation. Several studies have been shown that the combination therapy using both X-irradiation and antitumor drug is more effective to tumor compared with X-irradiation only. Previously Noguchi et al. showed the Hsp90 inhibitor 17AAG induced tumor cell death effectively with X-irradiation. Hsp90 is the enzymes activated by cellular stress and activates several tumor-related genes. To clarify whether or not the combination therapy of carbon ion beam and 17AAG is effective to solid tumors, we tested the growth of solid tumor with the combination of X-irradiation and 17AAG ${it in vivo}$ and compared the results from ${it in vitro}$ study.

Oral presentation

Radiosensitization by inhibition of homologous recombination repair combined with high LET heavy ion irradiation

Okayasu, Ryuichi*; Hirakawa, Hirokazu*; Noguchi, Miho; Yu, D.*; Takahashi, Momoko; Hirayama, Ryoichi*; Fujimori, Akira*

no journal, , 

17AAG, an Hsp90 inhibitor was shown to radiosensitize certain human tumor cells exposed to X-rays, while this sensitization was not clearly observed in normal human cells. The mechanism of this was suggested to come from inhibition of DNA double strand break (DSB) repair, particularly impairment of homologous recombination repair (HRR) pathway by this drug (Noguchi et al 2006). Key proteins associated with HRR seem to be affected by this inhibitor. To our surprise, tumor radiosensitization with 17AAG was also observed in cells exposed to high LET carbon ions (70 kev/um). Independently we also found that knockdown of BRCA2, a key HRR protein significantly radiosensitized human tumor cells. These results indicate that there seem to be a radio-sensitization mechanism associated with the combination of HRR inhibition and high LET radiation, and this may occur particularly in S-phase cells. Furthermore, we also used mouse xenograft model to examine the combined effect of 17AAG and high LET carbon irradiation. For this purpose, SQ5 human lung tumor cells were implanted on the leg of nude mice and the tumor growth was observed in the combined treatment as compared with radiation or drug treatment alone. Our preliminary results indicate that tumor growth was more inhibited in the 17AAG and carbon irradiation than carbon or 17AAG treatment alone. These data suggest that an effective tumor control might be obtained by combining an HRR inhibitor with high LET carbon irradiation.

Oral presentation

Study on distribution and migration of radioactive substances around the Fukushima Daiichi Nuclear Power Plant; Development of prediction models for a local area

Sato, Satoshi; Kinase, Sakae; Saito, Kimiaki; Takahashi, Tomoyuki*; Kurosawa, Naohiro*; Ryufuku, Susumu*; Hayashi, Hiroko*; Ishibashi, Kazufusa*; Sakamoto, Ryuichi*; Nemoto, Hisashi*

no journal, , 

no abstracts in English

Oral presentation

A Study on prediction models for caesium distribution within the 80 km radius of the Fukushima Daiichi Nuclear Power Plant

Kinase, Sakae; Takahashi, Tomoyuki*; Sato, Satoshi; Saito, Kimiaki; Sakamoto, Ryuichi*

no journal, , 

Oral presentation

Characterization of ${it OsNRAMP5}$ knockdown rice plants using high cadmium accumulating cultivar

Takahashi, Ryuichi*; Bashir, K.*; Ishimaru, Yasuhiro*; Senoura, Takeshi*; Sugimoto, Kazuhiko*; Ono, Kazuko*; Yano, Masahiro*; Suzui, Nobuo; Fujimaki, Shu; Nishizawa, Naoko*; et al.

no journal, , 

no abstracts in English

Oral presentation

Study on distribution and migration of radioactive substances around the Fukushima Daiichi Nuclear Power Plant, 8; Characterization of monitoring data by vehicle-borne survey in local area

Sato, Satoshi; Kinase, Sakae; Saito, Kimiaki; Takahashi, Tomoyuki*; Kanno, Mitsuhiro*; Hayashi, Hiroko*; Ishibashi, Kazufusa*; Kurosawa, Naohiro*; Sakamoto, Ryuichi*; Nemoto, Hisashi*

no journal, , 

no abstracts in English

Oral presentation

Ecological half-life of radioactive caesium within 80 km-radius of the Fukushima Daiichi Nuclear Power Plant

Kinase, Sakae; Sato, Satoshi; Takahashi, Tomoyuki*; Sakamoto, Ryuichi*; Saito, Kimiaki

no journal, , 

Oral presentation

Role of advection in atmospheric ammonia; A Case study at a Japanese lake basin influenced by agricultural ammonia sources

Katata, Genki*; Kubota, Tomohiro; Kuroda, Hisao*; Watanabe, Mirai*; Takahashi, Akiko*; Nakazato, Ryoji*; Tarui, Mika*; Matsumoto, Shunichi*; Nakagawa, Keita*; Numata, Yasuko*; et al.

no journal, , 

no abstracts in English

19 (Records 1-19 displayed on this page)
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