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Journal Articles

Fabrication of enzyme-degradable and size-controlled protein nanowires using single particle nano-fabrication technique

Omichi, Masaaki*; Asano, Atsushi*; Tsukuda, Satoshi*; Takano, Katsuyoshi*; Sugimoto, Masaki; Saeki, Akinori*; Sakamaki, Daisuke*; Onoda, Akira*; Hayashi, Takashi*; Seki, Shu*

Nature Communications (Internet), 5, p.3718_1 - 3718_8, 2014/04

 Times Cited Count:32 Percentile:81.72(Multidisciplinary Sciences)

Protein nanowires exhibiting specific biological activities hold promise for interacting with living cells and controlling and predicting biological responses such as apoptosis, endocytosis and cell adhesion. Here we report the result of the interaction of a single high-energy charged particle with protein molecules. Degradation of the human serum albumin nanowires was examined using trypsin. The biotinylated human serum albumin nanowires bound avidin, demonstrating the high affinity of the nanowires. Human serum albumin-avidin hybrid nanowires were also fabricated from a solid state mixture and exhibited good mechanical strength. The biotinylated human serum albumin nanowires can be transformed into nanowires exhibiting a biological function such as avidin-biotinyl interactions and peroxidase activity. The present technique is a versatile platform for functionalizing the surface of any protein molecule with an extremely large surface area.

Journal Articles

Micromachining of commodity plastics by proton beam writing and fabrication of spatial resolution test-chart for neutron radiography

Sakai, Takuro; Yasuda, Ryo; Iikura, Hiroshi; Nojima, Takehiro; Matsubayashi, Masahito; Kada, Wataru; Koka, Masashi; Sato, Takahiro; Okubo, Takeru; Ishii, Yasuyuki; et al.

Nuclear Instruments and Methods in Physics Research B, 306, p.299 - 301, 2013/07

 Times Cited Count:7 Percentile:54.8(Instruments & Instrumentation)

Journal Articles

Mach-Zehnder polymer waveguides fabricated using proton beam writing

Miura, Kenta*; Sato, Takahiro; Ishii, Yasuyuki; Koka, Masashi; Kiryu, Hiromu*; Ozawa, Yusuke*; Takano, Katsuyoshi*; Okubo, Takeru; Yamazaki, Akiyoshi; Kada, Wataru; et al.

JAEA-Review 2012-046, JAEA Takasaki Annual Report 2011, P. 126, 2013/01

Journal Articles

MFM observation of micrometer-sized magnetic patterns produced by heavy ion microbeam irradiation in FeRh films

Aiko, Kazuma*; Toki, Atsushi*; Matsui, Toshiyuki*; Iwase, Akihiro*; Sato, Takahiro; Takano, Katsuyoshi*; Koka, Masashi; Saito, Yuichi; Kamiya, Tomihiro

JAEA-Review 2012-046, JAEA Takasaki Annual Report 2011, P. 133, 2013/01

Journal Articles

Visualization of a single cluster particle track in polystyrene films

Asano, Atsushi*; Takano, Katsuyoshi*; Chiba, Atsuya; Saito, Yuichi; Marui, Hiromi*; Omichi, Masaaki*; Maeyoshi, Yuta*; Honsho, Yoshito*; Saeki, Akinori*; Yamada, Keisuke; et al.

JAEA-Review 2012-046, JAEA Takasaki Annual Report 2011, P. 163, 2013/01

Journal Articles

Fabrication of Mach-Zehnder polimer waveguides by a direct-drawing technique using a focused proton beam

Miura, Kenta*; Sato, Takahiro; Ishii, Yasuyuki; Kiryu, Hiromu*; Ozawa, Yusuke*; Koka, Masashi; Takano, Katsuyoshi*; Okubo, Takeru; Yamazaki, Akiyoshi; Kada, Wataru; et al.

Key Engineering Materials, 534, p.158 - 161, 2013/00

 Times Cited Count:5 Percentile:92.66

Journal Articles

A Line pair indicator made of Gd film for evaluating spatial resolution

Yasuda, Ryo; Matsubayashi, Masahito; Sakai, Takuro; Nojima, Takehiro; Iikura, Hiroshi; Katagiri, Masaki*; Takano, Katsuyoshi*; Pikuz, T.; Faenov, A.*

Physics Procedia, 43, p.196 - 204, 2013/00

 Times Cited Count:1 Percentile:56.8

Journal Articles

Visualization of focused proton beam dose distribution by atomic force microscopy using blended polymer films based on polyacrylic acid

Omichi, Masaaki*; Takano, Katsuyoshi*; Sato, Takahiro; Kamiya, Tomihiro; Ishii, Yasuyuki; Okubo, Takeru; Koka, Masashi; Kada, Wataru; Sugimoto, Masaki; Nishikawa, Hiroyuki*; et al.

Journal of Nanoscience and Nanotechnology, 12, p.7401 - 7404, 2012/09

 Times Cited Count:2 Percentile:12.81(Chemistry, Multidisciplinary)

Journal Articles

Microprocessing of arched bridge structures with epoxy resin by proton beam writing

Takano, Katsuyoshi*; Asano, Atsushi*; Maeyoshi, Yuta*; Marui, Hiromi*; Omichi, Masaaki*; Saeki, Akinori*; Seki, Shu*; Sato, Takahiro; Ishii, Yasuyuki; Kamiya, Tomihiro; et al.

Journal of Photopolymer Science and Technology, 25(1), p.43 - 46, 2012/07

 Times Cited Count:2 Percentile:7.78(Polymer Science)

Journal Articles

Ion-beam-induced luminescence analysis as diagnostic tool for microstructure patterning on diamond by proton beam writing

Kada, Wataru; Yokoyama, Akihito; Koka, Masashi; Takano, Katsuyoshi*; Sato, Takahiro; Kamiya, Tomihiro

Japanese Journal of Applied Physics, 51(6), p.06FB07_1 - 06FB07_5, 2012/06

 Times Cited Count:8 Percentile:37.83(Physics, Applied)

An Ion micro-Beam-Induced Luminescence (micro-IBIL) system was newly developed for the evaluation of the accuracy of proton beam writing on solid diamond surface. Fabrication of buried microstructures in bulk diamond (3.0 mm $$times$$ 3.0 mm $$times$$ 0.5 mm IIa single-crystal diamond) with a scanning microbeam was performed with using scanning focused 3 MeV proton microbeam. Photon counts of IBIL from the diamond were continuously observed and the changes were obtained during the process of PBW. An micro-IBIL image at a-band line of diamond crystal was successfully visualized as the PBW pattern on it through the monochromatic photon counting system of IBIL.

Journal Articles

Fabrication of concave and convex structure array consisted of epoxy long-nanowires by light and heavy ion beams lithography

Takano, Katsuyoshi*; Sugimoto, Masaki; Asano, Atsushi*; Maeyoshi, Yuta*; Marui, Hiromi*; Omichi, Masaaki*; Saeki, Akinori*; Seki, Shu*; Sato, Takahiro; Ishii, Yasuyuki; et al.

Transactions of the Materials Research Society of Japan, 37(2), p.237 - 240, 2012/06

Journal Articles

Fabrication of poly(9,9'-dioctylfluorene)-based nano- and microstructures by proton beam writing

Maeyoshi, Yuta*; Takano, Katsuyoshi*; Asano, Atsushi*; Marui, Hiromi*; Omichi, Masaaki*; Sato, Takahiro; Kamiya, Tomihiro; Ishii, Yasuyuki; Okubo, Takeru; Koka, Masashi; et al.

Japanese Journal of Applied Physics, 51(4R), p.045201_1 - 045201_4, 2012/04

 Times Cited Count:1 Percentile:5.05(Physics, Applied)

Journal Articles

MFM and PEEM observation of micrometre-sized magnetic dot arrays fabricated by ion-microbeam irradiation in FeRh thin films

Aiko, Kazuma*; Toki, Atsushi*; Matsui, Toshiyuki*; Iwase, Akihiro*; Sato, Takahiro; Takano, Katsuyoshi*; Koka, Masashi; Saito, Yuichi; Kamiya, Tomihiro; Okochi, Takuo*; et al.

Journal of Synchrotron Radiation, 19(2), p.223 - 226, 2012/03

 Times Cited Count:6 Percentile:35.76(Instruments & Instrumentation)

Journal Articles

Fast single-ion hit system for heavy-ion microbeam at TIARA cyclotron, 4

Yokota, Wataru; Sato, Takahiro; Okumura, Susumu; Kurashima, Satoshi; Miyawaki, Nobumasa; Kashiwagi, Hirotsugu; Yoshida, Kenichi; Koka, Masashi; Takano, Katsuyoshi*; Yokoyama, Akihito; et al.

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 159, 2012/01

The development of the fast single-ion hit system was continued from last year in order to improve the quality of microbeam and single-ion hit at the TIARA cyclotron of the Japan Atomic Energy Agency. The major subjects were reduction of miss hit, no hit on the targeted point by any ions in the single-ion-hit irradiation, and development of a real-time detection system of single-ion hit. A new microbeam of 400 MeV-Fe with a spot diameter of about 4 $$mu$$m was also developed and supplied to an experiment.

Journal Articles

3D micro-fabrication utilized superimposing technique with focused MeV ion beams

Takano, Katsuyoshi*; Sato, Takahiro; Kamiya, Tomihiro; Ishii, Yasuyuki; Okubo, Takeru; Koka, Masashi; Kada, Wataru; Sugimoto, Masaki; Seki, Shuhei*; Nishikawa, Hiroyuki*

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 162, 2012/01

Journal Articles

Fabrication of Y-junction waveguides using proton beam writing

Miura, Kenta*; Sato, Takahiro; Ishii, Yasuyuki; Koka, Masashi; Uehara, Masato*; Kiryu, Hiromu*; Takano, Katsuyoshi*; Okubo, Takeru; Yamazaki, Akiyoshi; Kada, Wataru; et al.

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 126, 2012/01

Journal Articles

Fabrication of polymer optical waveguides for the 1.5-$$mu$$m band using focused proton beam

Miura, Kenta*; Machida, Yuki*; Uehara, Masato*; Kiryu, Hiromu*; Ozawa, Yusuke*; Sasaki, Tomoyuki*; Hanaizumi, Osamu*; Sato, Takahiro; Ishii, Yasuyuki; Koka, Masashi; et al.

Key Engineering Materials, 497, p.147 - 150, 2012/00

 Times Cited Count:7 Percentile:96.61

Journal Articles

Fabrication of polymer optical waveguides for the 1.5-$$mu$$m band using focused proton beam

Miura, Kenta*; Machida, Yuki*; Uehara, Masato*; Kiryu, Hiromu*; Ozawa, Yusuke*; Sasaki, Tomoyuki*; Hanaizumi, Osamu*; Sato, Takahiro; Ishii, Yasuyuki; Koka, Masashi; et al.

Key Engineering Materials, 497, p.147 - 150, 2011/12

 Times Cited Count:6 Percentile:2.48

Journal Articles

Microbeam complex at TIARA; Technologies to meet a wide range of applications

Kamiya, Tomihiro; Takano, Katsuyoshi; Sato, Takahiro; Ishii, Yasuyuki; Nishikawa, Hiroyuki*; Seki, Shu*; Sugimoto, Masaki; Okumura, Susumu; Fukuda, Mitsuhiro*

Nuclear Instruments and Methods in Physics Research B, 269(20), p.2184 - 2188, 2011/10

 Times Cited Count:12 Percentile:71.79(Instruments & Instrumentation)

Journal Articles

Nano-micro processing of epoxy resin systems by ion beam lithography with multiple energies and species

Takano, Katsuyoshi; Sato, Takahiro; Ishii, Yasuyuki; Koka, Masashi; Kamiya, Tomihiro; Okubo, Takeru; Sugimoto, Masaki; Nishikawa, Hiroyuki*; Seki, Shu*

Transactions of the Materials Research Society of Japan, 36(3), p.305 - 308, 2011/09

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