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Fukui, Roman*; Saga, Ryo*; Matsuya, Yusuke; Tomita, Kazuo*; Kuwahara, Yoshikazu*; Ouchi, Kentaro*; Sato, Tomoaki*; Okumura, Kazuhiko*; Date, Hiroyuki*; Fukumoto, Manabu*; et al.
Scientific Reports (Internet), 12(1), p.1056_1 - 1056_12, 2022/01
Times Cited Count:11 Percentile:92.45(Multidisciplinary Sciences)Alive cancer cells after fractionated irradiations with 2 Gy X-rays per day for more than 30 days show clinically relevant radioresistant. Such radioresistance is experimentally interpreted to attributed to the increment of stem-like cell content. However, only an experimental approach cannot clarify the cell responses (DNA damage and cell death induction) of cancer stem cells, so the radioresistant mechanisms remain uncertain. In addition to the conventional cell experiments using radio-resistant cell lines established after fractionated irradiations, in this study we developed a mathematical model (so called integrated microdosimetric-kinetic (IMK) model) explicitly considering cancer stem-like cell content and DNA damage responses and investigated radioresistant mechanisms acquired after fractionated irradiations. The IMK model analysis suggested that the changes of stem-like cell fraction and DNA repair efficiency play important roles of radioresisitance acquired after irradiations. Considering these into the IMK model, we successfully reproduced the experimental survival of various cell lines and various irradiation conditions. This work would contribute to not only the precise understanding of the radioresistant mechanisms induced after irradiation but also predicting curative effects with high precision.
Kurihara, Momo*; Yasutaka, Tetsuo*; Aono, Tatsuo*; Ashikawa, Nobuo*; Ebina, Hiroyuki*; Iijima, Takeshi*; Ishimaru, Kei*; Kanai, Ramon*; Karube, Jinichi*; Konnai, Yae*; et al.
Journal of Radioanalytical and Nuclear Chemistry, 322(2), p.477 - 485, 2019/11
Times Cited Count:4 Percentile:40.00(Chemistry, Analytical)We assessed the repeatability and reproducibility of methods for determining low dissolved radiocesium concentrations in freshwater in Fukushima. Twenty-one laboratories pre-concentrated three of 10 L samples by five different pre-concentration methods (prussian-blue-impregnated filter cartridges, coprecipitation with ammonium phosphomolybdate, evaporation, solid-phase extraction disks, and ion-exchange resin columns), and activity of radiocesium was measured. The z-scores for all of the Cs results were within 2, indicating that the methods were accurate. The relative standard deviations (RSDs) indicating the variability in the results from different laboratories were larger than the RSDs indicating the variability in the results from each separate laboratory.
Tomita, Takuro*; Nishikino, Masaharu; Hasegawa, Noboru; Minami, Yasuo*; Takei, Ryota*; Baba, Motoyoshi*; Eyama, Tsuyoshi*; Takayoshi, Shodai*; Kaihori, Takeshi*; Morita, Toshimasa; et al.
Journal of Laser Micro/Nanoengineering, 9(2), p.137 - 142, 2014/06
Times Cited Count:5 Percentile:29.27(Nanoscience & Nanotechnology)Femtosecond laser ablation processes on platinum, gold, and tungsten were observed by the single shot pump and probe reflective imaging using a soft X-ray laser probe. To avoid the timing error due to the jitter, we adopted a posteriori correction technique by simultaneous measurement of timing between the pump and probe pulses for every single shot, using a soft X-ray streak camera. A clear difference was found in the temporal behavior of the dynamical response of the soft X-ray reflectivity depending on the irradiated laser fluence in these three materials. On the other hand, the narrow dark rings were found in Pt and W, while an additional bright ring was found outside the dark disk in Au. Our result gives the experimental data comparable with various numerical simulations.
Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Yasuyuki*; Al-Bataineh, H.*; Alexander, J.*; Aoki, Kazuya*; Aphecetche, L.*; Armendariz, R.*; et al.
Physical Review C, 83(6), p.064903_1 - 064903_29, 2011/06
Times Cited Count:184 Percentile:99.42(Physics, Nuclear)Transverse momentum distributions and yields for , and in collisions at = 200 and 62.4 GeV at midrapidity are measured by the PHENIX experiment at the RHIC. We present the inverse slope parameter, mean transverse momentum, and yield per unit rapidity at each energy, and compare them to other measurements at different collisions. We also present the scaling properties such as and scaling and discuss the mechanism of the particle production in collisions. The measured spectra are compared to next-to-leading order perturbative QCD calculations.
Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Yasuyuki*; Al-Bataineh, H.*; Alexander, J.*; Aoki, Kazuya*; Aphecetche, L.*; Aramaki, Y.*; et al.
Physical Review C, 83(4), p.044912_1 - 044912_16, 2011/04
Times Cited Count:9 Percentile:52.86(Physics, Nuclear)Measurements of electrons from the decay of open-heavy-flavor mesons have shown that the yields are suppressed in Au+Au collisions compared to expectations from binary-scaled collisions. Here we extend these studies to two particle correlations where one particle is an electron from the decay of a heavy flavor meson and the other is a charged hadron from either the decay of the heavy meson or from jet fragmentation. These measurements provide more detailed information about the interaction between heavy quarks and the quark-gluon matter. We find the away-side-jet shape and yield to be modified in Au+Au collisions compared to collisions.
Owada, Kenji; Tomita, Yusuke*
Nihon Butsuri Gakkai-Shi, 65(10), p.800 - 804, 2010/10
no abstracts in English
Owada, Kenji; Tomita, Yusuke*
Journal of the Physical Society of Japan, 79(1), p.011012_1 - 011012_10, 2010/01
Times Cited Count:25 Percentile:75.06(Physics, Multidisciplinary)Huang, X. S.*; Ono, Masao; Ueno, Hideto*; Iguchi, Yusuke*; Tomita, Takeshi; Okayasu, Satoru; Mashimo, Tsutomu
Journal of Applied Physics, 101(11), p.113502_1 - 113502_5, 2007/06
Times Cited Count:26 Percentile:67.69(Physics, Applied)A large linearly graded structure on atomic-scale up to 88 at%/mm with oriented grown crystals was formed in selenium-tellurium (Se-Te) semiconductor using a strong gravitational field of 1 million G level at 260 C. The lattice constants and the binding energies of Se and Te 3 electrons continuously changed along the direction of gravity accordingly, which indicated the formation of the graded band gap structure. The grown crystals showed the crystalline orientation with c-axis of hexagonal structure roughly perpendicular to the direction of gravity. It was found that the diffusion coefficient of sedimentation was larger than that of normal diffusion by more than 100 times, which suggested a different diffusion mechanism from the normal vacancy mechanism.
Hasegawa, Noboru; Nishikino, Masaharu; Kaihori, Takeshi*; Hirano, Yusuke; Morita, Toshimasa; Kawachi, Tetsuya; Yamagiwa, Mitsuru; Tomita, Takuro*; Minami, Yasuo*; Terakawa, Kota*; et al.
no journal, ,
no abstracts in English