Detection of a gas region in a human body across a therapeutic carbon beam by measuring low-energy photons

Yamaguchi, Mitsutaka; Nagao, Yuto; Kawachi, Naoki; Sato, Takahiro; Fujimaki, Shu; Kamiya, Tomihiro; Torikai, Kota*; Shimada, Hirofumi*; Sugai, Hiroyuki*; Sakai, Makoto*; et al.

International Journal of PIXE, 26(1&2), p.61 - 72, 2016/00

https://doi.org/10.1142/S0129083516500078

no abstracts in English

An Evaluation of three-dimensional imaging by use of Si/CdTe Compton cameras

Yamaguchi, Mitsutaka; Nagao, Yuto; Kawachi, Naoki; Fujimaki, Shu; Kamiya, Tomihiro; Odaka, Hirokazu*; Kokubun, Motohide*; Takeda, Shinichiro*; Watanabe, Shin*; Takahashi, Tadayuki*; et al.

Proceedings of 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC), 3 Pages, 2013/00

https://doi.org/10.1109/NSSMIC.2013.6829081

Beam range estimation by measuring bremsstrahlung

Yamaguchi, Mitsutaka; Torikai, Kota*; Kawachi, Naoki; Shimada, Hirofumi*; Sato, Takahiro; Nagao, Yuto; Fujimaki, Shu; Kokubun, Motohide*; Watanabe, Shin*; Takahashi, Tadayuki*; et al.

Physics in Medicine & Biology, 57(10), p.2843 - 2856, 2012/05

https://doi.org/10.1088/0031-9155/57/10/2843

Development of head module for multi-head Si/CdTe Compton camera for medical applications

Yamaguchi, Mitsutaka; Kawachi, Naoki; Suzui, Nobuo; Fujimaki, Shu; Kamiya, Tomihiro; Odaka, Hirokazu*; Ishikawa, Shinnosuke*; Kokubun, Motohide*; Watanabe, Shin*; Takahashi, Tadayuki*; et al.

Nuclear Instruments and Methods in Physics Research A, 648(Suppl.1), p.S2 - S7, 2011/08

https://doi.org/10.1016/j.nima.2011.02.040

We are constructing a three-dimensional imaging system for medical and biological applications. The system will allow simultaneous imaging at high spatial and energy resolutions across a wide energy range, from several tens of keV to a few MeV. In this work, one prototype head module have been developed for a multi-head Si/CdTe Compton camera system. The performance of the prototype was evaluated with a sealed Ba-133 radiation source. The experiments confirmed that the imaging results were consistent with actual source position. In addition to the resolution for the parallel directions to the detector surface, the position resolution was evaluated for the depth direction at a point in near region of the head-module. These position resolutions were well reproduced by Monte Carlo simulation results.

Development of an image reconstruction method for quantitative profiling of -ray sources at close range using Si/CdTe Compton camera

Nagao, Yuto; Yamaguchi, Mitsutaka; Kawachi, Naoki; Fujimaki, Shu; Kamiya, Tomihiro; Takeda, Shinichiro*; Odaka, Hirokazu*; Watanabe, Shin*; Kokubun, Motohide*; Takahashi, Tadayuki*; et al.

no journal, , 

A conventional -ray imaging system such as a gamma camera and SPECT has a fundamental problem that imposes a tradeoff between sensitivity and spatial resolution and restricts -ray energy to low because of the physical constraints resulting from the mechanical collimation. On the other hand, a Compton camera, which applies kinematics of Compton scattering to the electronic collimation, is a next generation -ray imaging system which decouples the tradeoff between sensitivity and spatial resolution and covers a wide range of energy. We study an application of a Si/CdTe semiconductor Compton camera being developed for space observation to in vivo tracer imaging in medicine and biology. Particularly, it is essential for a medical and biological application to estimate quantitative distribution of tracers in a field close to the camera. We developed an image reconstruction method to realize quantitative profiling of -ray emitting sources.

An Evaluation of tomographic image-quality for a multi-head Si/CdTe semiconductor Compton camera for medical and biological applications by a simulation study

Yamaguchi, Mitsutaka; Sakai, Makoto*; Nagao, Yuto; Kawachi, Naoki; Fujimaki, Shu; Arakawa, Kazuo*; Kamiya, Tomihiro; Odaka, Hirokazu*; Kokubun, Motohide*; Takeda, Shinichiro*; et al.

no journal, , 

no abstracts in English

Detection of a gap across a particle-beam track by measuring 63-68 keV photons

Yamaguchi, Mitsutaka; Nagao, Yuto; Kawachi, Naoki; Fujimaki, Shu; Kamiya, Tomihiro; Torikai, Kota*; Shimada, Hirofumi*; Sugai, Hiroyuki*; Sakai, Makoto*; Arakawa, Kazuo*; et al.

no journal, , 

no abstracts in English

Substantiative experiments of distortion correction for novel Si/CdTe Compton camera

Kawachi, Naoki; Yamaguchi, Mitsutaka; Nagao, Yuto; Suzui, Nobuo; Fujimaki, Shu; Kamiya, Tomihiro; Odaka, Hirokazu*; Kokubun, Motohide*; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; et al.

no journal, , 

Development of a head module for multi-head Si/CdTe Compton camera

Yamaguchi, Mitsutaka; Kamiya, Tomihiro; Kawachi, Naoki; Suzui, Nobuo; Fujimaki, Shu; Odaka, Hirokazu*; Ishikawa, Shinnosuke*; Kokubun, Motohide*; Watanabe, Shin*; Takahashi, Tadayuki*; et al.

no journal, , 

We are constructing a three-dimensional imaging system for medical and biological applications as a device that can provide simultaneous imaging, having high spatial and energy resolutions and wide energy range from several tens keV to a few MeV, by diverting the most advanced space-observation technology, Si/CdTe semiconductor Compton camera, developed in ISAS/JAXA. The Si/CdTe Compton camera was developed under the assumption that the use of moderate temperature and the Analog ASIC for signal processing. Moreover, because the solid and thin scattering layer allows close placement of the measured object, good angular resolution corresponds to good spatial resolution directly. These aspects allow construction of compact medical system. In contrast to space-observation use, three-dimensional imaging ability becomes important for life science research. In order to achieve a good three-dimensional spatial resolution, modularizing the Compton camera into a small camera head and allowing multi-angle imaging with multi-head structure is required. In this work, a head module has been developed as a prototype module of the multi-head system. Sensor and circuit modules are closely arranged and put in a compact vacuum-insulating cylindrical housing. Each of camera heads will be fixed on robot arms and be able to adjust the positions and the directions. Performance evaluation test was made for the prototype module with a sealed Ba-133 radiation source. We confirmed that the imaging result is consistent with the source positioning. The angular resolution measure, abbreviated as ARM, was estimated to be 4.5 degree. The result of the test was compared with a Monte Carlo simulation study. We will report the details of the prototype module and the result of the performance evaluation test. The expecting three-dimensional performance will also be reported.

Development of a multi-head Si/CdTe Compton camera for medical and Biological application

Yamaguchi, Mitsutaka; Kawachi, Naoki; Suzui, Nobuo; Fujimaki, Shu; Kamiya, Tomihiro; Odaka, Hirokazu*; Kokubun, Motohide*; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; Watanabe, Shin*; et al.

no journal, , 

no abstracts in English