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Journal Articles

Measurement of neutron production double-differential cross-sections on carbon bombarded with 430 MeV/nucleon carbon ions

Itashiki, Yutaro*; Imabayashi, Yoichi*; Shigyo, Nobuhiro*; Uozumi, Yusuke*; Satoh, Daiki; Kajimoto, Tsuyoshi*; Sanami, Toshiya*; Koba, Yusuke*; Matsufuji, Naruhiro*

Journal of Radiation Protection and Research, 41(4), p.344 - 349, 2016/12

Carbon ion therapy has achieved satisfactory results because of high curability and minimally invasiveness. However, patients have a risk to get a secondary cancer. In order to estimate the risk, it is essential to understand particle transportation and nuclear reactions in the patient's body. The particle transport Monte Carlo simulation code is a useful tool to understand them. Since the code validation for heavy ion incident reactions is not enough, the experimental data of the elementary reaction processes is needed. We measured neutron production double-differential cross-sections (DDXs) on a carbon bombarded with 430 MeV/nucleon carbon beam which is a possible candidate of future therapy beam. The experiment was performed at PH2 beam line of the HIMAC of National Institute of Radiological Sciences. The 430 MeV/nucleon carbon beam was irradiated on a 5 cm $${times}$$ 5 cm $${times}$$ 1 cm graphite target rotated 45$$^{circ}$$ to the beam axis. The beam intensity was set to 10$$^{5}$$ particles / spill. A 0.5 mm thick NE102A plastic scintillator was placed to monitor the beam intensity. Neutrons produced in the target were measured with two sizes of NE213 liquid organic scintillators located at six angles of 15, 30, 45, 60, 75, and 90$$^{circ}$$. The 5.08 cm long one was used to obtain the neutron spectra from 1 MeV to 10 MeV and the 12.7 cm long one was used above 5 MeV. The 2 mm thick NE102A plastic scintillators to discriminate charged particles were set in front of the neutron detectors. The kinetic energies of neutrons were determined by the time-of-flight (TOF) method. Background neutrons were estimated by a measurement with iron shadow bars between the target and each neutron detector. An electronic circuit for data acquisition consisted of NIM and CAMAC modules. The experimental data was compared with calculated results obtained by Monte Carlo simulation codes as PHITS. The PHITS code reproduced the experimental data well.

Journal Articles

Distributions of neutron yields and doses around a water phantom bombarded with 290-MeV/nucleon and 430-MeV/nucleon carbon ions

Satoh, Daiki; Kajimoto, Tsuyoshi*; Shigyo, Nobuhiro*; Itashiki, Yutaro*; Imabayashi, Yoichi*; Koba, Yusuke*; Matsufuji, Naruhiro*; Sanami, Toshiya*; Nakao, Noriaki*; Uozumi, Yusuke*

Nuclear Instruments and Methods in Physics Research B, 387, p.10 - 19, 2016/11

 Times Cited Count:2 Percentile:57.25(Instruments & Instrumentation)

Double-differential neutron yields from a water phantom bombarded with 290-MeV/nucleon and 430-MeV/nucleon carbon ions were measured at emission angles of 15$$^{circ}$$, 30$$^{circ}$$, 45$$^{circ}$$, 60$$^{circ}$$, 75$$^{circ}$$, and 90$$^{circ}$$ using the neutron-detection system constituting of liquid organic scintillators. The angular distributions of neutron yields and effective doses around the phantom were obtained by integrating the double-differential neutron yields and applying the fluence-to-effective dose conversion coefficients. The experimental data were compared with results of the Monte-Carlo simulation code PHITS. The PHITS results showed good agreement with the measured data. From the results, we concluded that the PHITS simulation is applicable to the dose estimation at carbon-therapy facilities.

Journal Articles

Measurement of neutron production cross sections from heavy ion induced reaction

Shigyo, Nobuhiro*; Uozumi, Yusuke*; Imabayashi, Yoichi*; Itashiki, Yutaro*; Satoh, Daiki; Kajimoto, Tsuyoshi*; Sanami, Toshiya*; Koba, Yusuke*; Takada, Masashi*; Matsufuji, Naruhiro*; et al.

JAEA-Conf 2014-002, p.81 - 87, 2015/02

Cancer therapy using heavy ion beam has been adopted as highly advanced medical treatment by reason of its clinical advantages. It has become more important to estimate the risk of secondary cancer from recent survey. During treatment, secondary particles such as neutrons and -rays are producedby heavy ion induced nuclear reactions in a patient body as well as beam delivery apparatuses. For the risk assessment of secondary cancer, it is essential to know contribution of secondary neutrons by extra dose to organs in the vicinity of the irradiated tumor because the secondary neutron has a long flight path length and gives undesired dose to normal tissues in a wide volume. The experimental data of neutron energy spectra are required for dose estimations with high accuracy. Especially, precise data around neutron energy of 1 MeV is required because neutron of the energy region has a large relative biological eectiveness. Estimation of the secondary neutron yield data is important for estimation of radiation safety on both of workers and public in treatment facilities.

Journal Articles

Measurement of proton, deuteron, and triton production double differential cross sections on carbon by 290 MeV/nucleon Ar ions

Kajimoto, Tsuyoshi*; Hashiguchi, Taro*; Shigyo, Nobuhiro*; Satoh, Daiki; Uozumi, Yusuke*; Song, T. Y.*; Lee, C. W.*; Kim, J. W.*; Yang, S. C.*; Koba, Yusuke*; et al.

JAEA-Conf 2014-002, p.127 - 132, 2015/02

Particle transport Monte Carlo codes such as PHITS, FLUKA and so on are used for radiation safety design of high energy accelerators. The validity of code is con rmed by comparison with many experimental data. In this study, we report proton, deuteron, and triton production double differential cross sections (DDXs) from a graphite target by 290 MeV/nucleon Ar ions. The measured spectra are compared with those calculated by PHITS and FLUKA codes.

Journal Articles

Measurement of 100- and 290-MeV/A carbon incident neutron production cross sections for carbon, nitrogen and oxygen

Shigyo, Nobuhiro*; Uozumi, Yusuke*; Uehara, Haruhiko*; Nishizawa, Tomoya*; Mizuno, Takafumi*; Takamiya, Masanori*; Hashiguchi, Taro*; Satoh, Daiki; Sanami, Toshiya*; Koba, Yusuke*; et al.

Nuclear Data Sheets, 119, p.303 - 306, 2014/05

 Percentile:100(Physics, Nuclear)

Heavy ion cancer therapy has been increased by reason of its clinical advantages. During the treatment, the secondary particles such as neutron and $$gamma$$-ray are produced by nuclear reactions of a heavy ion incidence on a nucleus in a patient body. Estimation of the secondary neutrons yields data is essential for assessment of radiation safety on both of workers and public in treatment facilities. We have measured the neutron yields from carbon ion incidence on carbon, nitrogen and oxygen targets in wide angular range from 15$$^{circ}$$ to 90$$^{circ}$$ with 100- and 290-MeV/u.

Journal Articles

Measurement of neutron yields from a water phantom bombarded by 290 MeV/u carbon ions

Shigyo, Nobuhiro*; Uozumi, Yusuke*; Uehara, Haruhiko*; Nishizawa, Tomoya*; Hirabayashi, Keiichi*; Satoh, Daiki; Sanami, Toshiya*; Koba, Yusuke*; Takada, Masashi*; Matsufuji, Naruhiro*

Progress in Nuclear Science and Technology (Internet), 4, p.709 - 712, 2014/04

Heavy ion cancer therapy has been increased by reason of its clinical advantages. During the treatment, the secondary particles such as neutron and $$gamma$$-ray are produced by nuclear reactions of a heavy ion incidence on a nucleus in a patient body. Estimation of the secondary neutrons yields data is essential for assessment of radiation safety on both of workers and public in treatment facilities. Neutron energy spectra from a water phantom simulating the patient body were obtained at GSI only for forward directions. We measured the neutron yields from carbon ion incident on a water phantom in wide angular range from 15$$^{circ}$$ to 90$$^{circ}$$ with the therapeutic ion energy.

Journal Articles

Measurement of 100 MeV/u carbon incident neutron production cross sections on a carbon target

Shigyo, Nobuhiro*; Uozumi, Yusuke*; Uehara, Haruhiko*; Nishizawa, Tomoya*; Mizuno, Takafumi*; Satoh, Daiki; Sanami, Toshiya*; Koba, Yusuke*; Takada, Masashi*; Matsufuji, Naruhiro*

JAEA-Conf 2013-002, p.137 - 142, 2013/10

Heavy ion cancer therapy has been increased by reason of its clinical advantages. During the treatment, the secondary particles such as neutron and $$gamma$$-ray are produced by nuclear reactions of a heavy ion incidence on a nucleus in a patient body. Estimation of double differential cross sections of secondary neutron is important to risk assessment of extra dose to organs in the vicinity of the irradiated tumor. Accurate data in neutron energy around 1 MeV is required because neutron in the energy region has large relative biological effectiveness. Neutron double differential cross sections by inducing 290 MeV/u carbon ion to bio-elements have been obtained experimentally. In order to have knowledge of neutron production by deceleration carbon in a human body, we measured the neutron yields from carbon ion incidence on a carbon target of neutron energy below 1 MeV in wide angular range from 15$$^{circ}$$ to 90$$^{circ}$$ with 100 MeV/u.

Journal Articles

Measurement of neutron- and photon-production cross sections from heavy-ion reactions on tissue equivalent elements

Uozumi, Yusuke*; Shigyo, Nobuhiro*; Uehara, Haruhiko*; Nishizawa, Tomoya*; Mizuno, Takafumi*; Satoh, Daiki; Sanami, Toshiya*; Koba, Yusuke*; Takada, Masashi*; Matsufuji, Naruhiro*; et al.

HIMAC-140, p.234 - 235, 2013/08

In the heavy-ion radiotherapy, considerable discussion has been attracted regarding the potential for second cancer induction by secondary neutrons produced from the primary heavy-ion fragmentation. We have started new measurements at 100 MeV/u to investigate the neutron production by heavy ions decelerating in a patient body.

Journal Articles

Intranuclear cascade with emission of light fragment code implemented in the transport code system PHITS

Sawada, Yusuke*; Uozumi, Yusuke*; Nogamine, Sho*; Yamada, Takehiro*; Iwamoto, Yosuke; Sato, Tatsuhiko; Niita, Koji*

Nuclear Instruments and Methods in Physics Research B, 291, p.38 - 44, 2012/11

 Times Cited Count:10 Percentile:25.58(Instruments & Instrumentation)

The Intranuclear cascade with emission of light fragment (INC-ELF) code has been developed and implemented in the particle and heavy ion transport code system (PHITS). The INC-ELF code explicitly includes nucleon correlations within the framework of the INC model to describe light fragment emissions from nuclear spallation reactions. In addition to the degrees of freedom of nucleons, the developed code also accounts for pions, $$Delta$$$$s$$ and $$N$$$$^{*}$$$$s$$, and it can cover the energy range up to 3 GeV. The predictive capabilities of the ELF/PHITS system have been verified through comparison with a diverse set of experimental observations. As a result, our ELF/PHITS code has demonstrated strong predictive capability for all of these data, although areas requiring future study remain due to the lack of experimental data on high-energy cluster production.

Journal Articles

Measurements of neutron- and photon-production cross sections from heavy-ion reactions on tissue equivalent elements

Uozumi, Yusuke*; Shigyo, Nobuhiro*; Kajimoto, Tsuyoshi*; Hirabayashi, Keiichi*; Uehara, Haruhiko*; Nishizawa, Tomoya*; Satoh, Daiki; Sanami, Toshiya*; Koba, Yusuke*; Takada, Masashi*; et al.

HIMAC-138, p.237 - 238, 2012/08

In the heavy-ion radiotherapy, considerable discussion has been attracted regarding the potential for second cancer induction by secondary neutrons produced from the primary heavy-ion fragmentation. It is important to measure energy-angle double-differential cross sections (DDXs) of neutron- and photon-productions in heavy-ion nuclear reactions. Since it is notoriously hard to measure the spectral cross sections of neutrons in an energy range of around 1 MeV where the RBE value reaches at its maximum. In the project by last year, experiments were carried out at the synchrotron HIMAC of NIRS, Japan. The beams were $$^{12}$$C and $$^{16}$$O of 290 MeV/u and bombarded a carbon target. In measurements of neutrons and photons were used liquid scintillator detectors of 5" and 2". We have succeeded to lower the neutron energy threshold down to 0.6 MeV. The present results for neutron productions are in reasonable agreements with PHITS. Since our goal in technical aspects has been fulfilled, measurements will be continued for other reactions.

Journal Articles

Deuteron-production double-differential cross sections for 300- and 392-MeV proton-induced reactions deduced from experiment and model calculation

Uozumi, Yusuke*; Sawada, Yusuke*; Mzhavia, A.*; Nogamine, Sho*; Iwamoto, Hiroki; Kin, Tadahiro; Hohara, Shinya*; Wakabayashi, Genichiro*; Nakano, Masahiro*

Physical Review C, 84(6), p.064617_1 - 064617_11, 2011/12

 Times Cited Count:10 Percentile:35.86(Physics, Nuclear)

Deuteron production from intermediate-energy proton-nucleus interactions was investigated through experiments and model calculations, mainly to develop a theoretical model by elucidating the mechanism of cluster production. Spectral double-differential cross sections were measured for inclusive ($$p$$, $$xd$$) reactions on five targets in the periodic table, namely $$^{12}$$C, $$^{27}$$Al, $$^{51}$$V, $$^{93}$$Nb, and $$^{197}$$Au, at beam energies of 300 and 392 MeV. The cross sections were determined in almost the entire outgoing energy range from the highest down to 30 MeV and at laboratory angles from 20$$^{circ}$$ to 104$$^{circ}$$. To interpret the measured spectra, we proposed a new model that includes the nucleon correlations of the initial- and final-state interactions to describe cluster knockout and pickup within the intranuclear cascade model. The results of the model calculations showed reasonable agreements with those of the experiments. Moreover, the model indicated reasonable predictive power for the ($$p$$, $$^{3}$$He$$x$$), ($$p$$, $$x$$$$alpha$$), and ($$d$$, $$xd$$) reactions measured elsewhere.

Journal Articles

Measurement of neutron- and photon-production cross sections from heavy-ion reactions on tissue equivalent elements

Uozumi, Yusuke*; Shigyo, Nobuhiro*; Kajimoto, Tsuyoshi*; Moriguchi, Daisuke*; Ueyama, Masahiko*; Yoshioka, Masakatsu*; Satoh, Daiki; Sanami, Toshiya*; Koba, Yusuke*; Takada, Masashi*; et al.

HIMAC-136, p.248 - 249, 2011/11

no abstracts in English

Journal Articles

Neutron-production double-differential cross sections from heavy-ion interactions

Satoh, Daiki; Moriguchi, Daisuke*; Kajimoto, Tsuyoshi*; Koba, Yusuke*; Nakamura, Yasuhiro*; Shigyo, Nobuhiro*; Ueyama, Masahiko*; Uozumi, Yusuke*; Yoshioka, Masakatsu*; Matsufuji, Naruhiro*; et al.

Journal of the Korean Physical Society, 59(2), p.1741 - 1744, 2011/08

 Times Cited Count:3 Percentile:66.9(Physics, Multidisciplinary)

The data of neutron production from heavy-ion interactions are of great importance for the dose assessment in heavy-ion therapy. We have already evaluated the data of neutron production for thick targets, in which the incident heavy ions completely stop, by the measurements and the reevaluation of the existing data reported by Kurosawa et al. As a next step of the research, we plan to evaluate the neutron-production cross-section data for thin targets. These data are useful to understand the mechanism of heavy-ion interaction, and improve the reaction model in particle transport codes. The previously reported cross-section data by Iwata et al. were revised by using a new set of neutron-detection efficiency values calculated with SCINFUL-QMD code. While the original data gave the larger values than the predictions of particle transport codes above 200 MeV due to the underestimation of the efficiencies, it was improved by this revision. In addition, we have started the new cross-section measurements at HIMAC. All the data of neutron-production cross sections were compared with the predictions of particle transport codes.

Journal Articles

Measurement of neutron-production double-differential cross-sections on carbon bombarded with 290-MeV/nucleon carbon and oxygen ions

Satoh, Daiki; Moriguchi, Daisuke*; Kajimoto, Tsuyoshi*; Uehara, Haruhiko*; Shigyo, Nobuhiro*; Ueyama, Masahiko*; Yoshioka, Masakatsu*; Uozumi, Yusuke*; Sanami, Toshiya*; Koba, Yusuke*; et al.

Nuclear Instruments and Methods in Physics Research A, 644(1), p.59 - 67, 2011/07

 Times Cited Count:11 Percentile:24.46(Instruments & Instrumentation)

Neutron-production double-differential cross sections on carbon-carbon and oxygen-carbon reactions with incident heavy-ion energy of 290 MeV/nucleon were measured by time-of-flight method using liquid organic scintillators. By use of a detection system specialized for low-energy neutrons, the cross sections were obtained in a wide energy region from several hundred MeV down to 0.6 MeV for the oxygen-ion incidences. The experimental data were compared with the calculation results using the Monte-Carlo simulation code, PHITS. The PHITS results gave an overall agreement with the measured data within a factor of two.

Journal Articles

Study of neutron and photon production cross sections for second cancer risk assessment in heavy-ion therapy

Uozumi, Yusuke*; Iwamoto, Hiroki*; Koba, Yusuke*; Matsufuji, Naruhiro*; Sanami, Toshiya*; Satoh, Daiki; Shigyo, Nobuhiro*; Takada, Masashi*; Ueyama, Masahiko*; Yoshioka, Masakatsu*; et al.

Progress in Nuclear Science and Technology (Internet), 1, p.114 - 117, 2011/02

It is important to assess and suppress the potential for second cancer induction by secondary neutrons produced in primary heavy-ion fragmentation in patient body. Since it is very difficult to measure high-energy neutron doses in mixed radiation fields, a Monte-Carlo simulation approach has attracted much attention as an alternative for neutron dose estimation. It is notoriously hard to reproduce the spectral cross sections of neutrons from high-energy heavy-ion collisions. We, therefore, have planned experiments to measure energy-angle double-differential cross sections of nuclear reactions.

Journal Articles

Proton-production double-differential cross sections for 300-MeV and 392-MeV proton-induced reactions

Iwamoto, Hiroki; Imamura, Minoru*; Koba, Yusuke*; Fukui, Yoshinori*; Wakabayashi, Genichiro*; Uozumi, Yusuke*; Kin, Tadahiro; Iwamoto, Yosuke; Hohara, Shinya*; Nakano, Masahiro*

Physical Review C, 82(3), p.034604_1 - 034604_8, 2010/09

 Times Cited Count:8 Percentile:42.32(Physics, Nuclear)

We investigate proton-production double-differential cross sections (DDXs) for 300- and 392-MeV proton-induced reactions on O, V, Tb, Ta, Au, Pb, and Bi. Emitted proton energies are measured with stacked scintillator spectrometers by the $$Delta$$$$E$$-$$E$$ technique. Experimental results are compared with the intranuclear cascade (INC) and quantum molecular dynamics models. Although both models can reproduce spectral DDXs, there is a difference at the most forward and backward angles. The cause of these differences is discussed in terms of the refraction caused by the nuclear potential. Angular distributions of the present data are well accounted for by the Kalbach systematics plus INC one-step calculations. The quasi-free-scattering contribution increases with decreasing target mass and increasing emission energy.

Oral presentation

Study for neutron production cross sections by heavy ion interactions, 2; Evaluation of cross sections, and comparison with predictions of Monte Carlo codes

Satoh, Daiki; Moriguchi, Daisuke*; Nakamura, Yasuhiro*; Kajimoto, Tsuyoshi*; Ueyama, Masahiko*; Yoshioka, Masakatsu*; Koba, Yusuke*; Shigyo, Nobuhiro*; Uozumi, Yusuke*; Matsufuji, Naruhiro*; et al.

no journal, , 

Neutron production double differential cross sections have been measured at HIMAC in National Institute of Radiological Sciences. The cross sections were obtained in the energy region from a few MeV to several hundred MeV. In addition, we got the systematic cross section data by revising the detection efficiencies in the existing data. All the data were compared with the predictions of Monte Carlo simulation codes. While the codes show a good agreement in the backward angular region, they can not reproduce the peak structure observed in the forward angular region. This indicates that the nucleus-nucleus reaction model in the simulation codes must be revised.

Oral presentation

Study for neutron production cross sections by heavy ion interactions, 3; Neutron production double differential cross sections of oxygen upon 290 MeV/u carbon ion incidences

Satoh, Daiki; Shigyo, Nobuhiro*; Uozumi, Yusuke*; Moriguchi, Daisuke*; Kajimoto, Tsuyoshi*; Yoshioka, Masakatsu*; Ueyama, Masahiko*; Sanami, Toshiya*; Koba, Yusuke*; Matsufuji, Naruhiro*; et al.

no journal, , 

Neutron-production double-differential cross sections from heavy-ion interactions have been measured at Heavy-Ion Medical Accelerator in Chiba (HIMAC) of National Institute of Radiological Sciences (NIRS), Japan. 290-MeV/u O ions were bombarded upon a carbon target. The outgoing neutrons from the target were measured by a detection system that consist of two sizes of liquid organic scintillators with Time-of-Flight (TOF) technique in order to obtain a wide range of neutron spectrum from sub MeV to several hundred MeV. We have successfully measured the cross sections with a good precision.

Oral presentation

Measurement of carbon ion incident neutron production double differential cross sections for carbon target

Shigyo, Nobuhiro*; Uozumi, Yusuke*; Kajimoto, Tsuyoshi*; Moriguchi, Daisuke*; Ueyama, Masahiko*; Yoshioka, Masakatsu*; Koba, Yusuke*; Nakamura, Yasuhiro*; Satoh, Daiki; Sanami, Toshiya*; et al.

no journal, , 

Radiation dose by neutrons produced by proton and heavy ion induced nuclear reactions around tumor is essential for dose assessment in proton and heavy ion radiotherapies. Double differential cross section (DDX) of neutron production is one of important physical quantities for dose estimation by radiation transport codes. Some experimental data of neutron production DDXs have been reported above 5 MeV of neutron energy for heavy ion incident reactions. Neutron production DDX for carbon ion incidence on carbon target was measured at the Heavy Ion Medical Accelerator in Chiba (HIMAC) including low neutron energy region for validation of radiation transport codes. Incident carbon energy was 290 MeV/u. NE213 liquid organic scintillators were deployed as neutron detectors and placed at 15$$^{circ}$$, 30$$^{circ}$$ 45$$^{circ}$$, 60$$^{circ}$$, 75$$^{circ}$$ and 90$$^{circ}$$. Neutron energies were determined by the time-of-flight methods. Neutron detection efficiency was calculated by the SCINFUL-QMD code. The obtained minimum neutron energy was about 2.8 MeV. The experimental data of neutron production DDX was compared with that by one of radiation transport codes, PHITS.

Oral presentation

Measurement of neutron yields from a water phantom induced by 290 MeV/u carbon beam

Shigyo, Nobuhiro*; Uozumi, Yusuke*; Uehara, Haruhiko*; Nishizawa, Tomoya*; Hirabayashi, Keiichi*; Satoh, Daiki; Sanami, Toshiya*; Koba, Yusuke*; Takada, Masashi*; Matsufuji, Naruhiro*

no journal, , 

Heavy ion cancer therapy has been increased by reason of its clinical advantages. During the treatment, the secondary particles such as neutron and $$gamma$$-ray are produced by nuclear reactions of a heavy ion incidence on a nucleus in a patient body. Estimation of the secondary neutrons yields data is essential for assessment of radiation safety on both of workers and public in treatment facilities. Neutron energy spectra from a water phantom simulating the patient body were obtained at GSI only for forward directions. We measured the neutron yields from carbon ion incident on a water phantom in wide angular range from 15$${^circ}$$ to 90$${^circ}$$ with the therapeutic ion energy.

23 (Records 1-20 displayed on this page)